Repeated confocal imaging of individual dendritic spines in the living hippocampal slice: evidence for changes in length and orientation associated with chemically induced LTP

Long‐lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path

1973 • 7,118 citations

Gonadal steroids regulate dendritic spine density in hippocampal pyramidal cells in adulthood

1990 • 1,352 citations

Naturally occurring fluctuation in dendritic spine density on adult hippocampal pyramidal neurons

1990 • 1,080 citations

Dendritic spines of CA 1 pyramidal cells in the rat hippocampus: serial electron microscopy with reference to their biophysical characteristics

1989 • 1,069 citations

Dendritic Spines: Cellular Specializations Imparting Both Stability and Flexibility to Synaptic Function

1994 • 970 citations

Synaptic patterns on different cell types in the different laminae of the cat visual cortex. An electron microscope study

1968 • 947 citations

Structural Changes Accompanying Memory Storage

1993 • 851 citations

Tissue-plasminogen activator is induced as an immediate–early gene during seizure, kindling and long-term potentiation

1993 • 841 citations

Presynaptic enhancement shown by whole-cell recordings of long-term potentiation in hippocampal slices

1990 • 803 citations

Fluorescent carbocyanine dyes allow living neurons of identified origin to be studied in long-term cultures.

1986 • 785 citations

Neuron numbers and dendritic extent in normal aging and Alzheimer's disease

1987 • 769 citations

Histologie du Système Nerveux de Lʼhomme et des Vertébrés

1998 • 704 citations

Presynaptic mechanism for long-term potentiation in the hippocampus

1990 • 691 citations

Quantal analysis of synaptic potentials in neurons of the central nervous system.

1990 • 578 citations

In situ hybridization histochemistry of Ca2+/calmodulin-dependent protein kinase in developing rat brain

1990 • 566 citations

Long-term potentiation phenomena in the rat limbic forebrain

1983 • 562 citations

Transient and enduring morphological correlates of synaptic activity and efficacy change in the rat hippocampal slice

1984 • 531 citations

Dendritic spines as individual neuronal compartments for synaptic Ca2+ responses

1991 • 487 citations

Brief bursts of high-frequency stimulation produce two types of structural change in rat hippocampus.

1980 • 474 citations

Long-lasting morphological changes in dendritic spines of dentate granular cells following stimulation of the entorhinal area

1977 • 450 citations

Postsynaptic contribution to long-term potentiation revealed by the analysis of miniature synaptic currents

1992 • 372 citations

Multivesicular release from excitatory synapses of cultured hippocampal neurons

1994 • 333 citations

Subsynaptic Plate Perforations: Changes with Age and Experience in the Rat

1978 • 328 citations

Novel form of long-term potentiation produced by a K+channel blocker in the hippocampus

1991 • 321 citations

Brain fodrin: substrate for calpain I, an endogenous calcium-activated protease.

1984 • 294 citations

Contributions of dendritic spines and perforated synapses to synaptic plasticity

1990 • 289 citations

Amplitude fluctuations of

1994 • 288 citations

The Hippocampal‐Dentate Complex in Temporal Lobe Epilepsy

1974 • 281 citations

Quantal analysis and synaptic anatomy — integrating two views of hippocampal plasticity

1993 • 280 citations

Presynaptic release probability influences the locus of long-term potentiation

1992 • 278 citations

Synaptic correlates of associative potentiation/depression: an ultrastructural study in the hippocampus

1983 • 278 citations

Swelling of dendritic spines in the fascia dentata after stimulation of the perforant fibers as a mechanism of post-tetanic potentiation

1975 • 275 citations

Induction of long-term potentiation is associated with an increase in the number of axospinous synapses with segmented postsynaptic densities

1991 • 272 citations

The anatomy of a memory: convergence of results across a diversity of tests

1988 • 267 citations

Morphological variations in the dendritic spines of the neocortex

1969 • 259 citations

Protein kinase C inhibitors eliminate hippocampal long-term potentiation

1987 • 252 citations

Age‐related loss of axospinous synapses formed by two afferent systems in the rat dentate gyrus as revealed by the unbiased stereological dissector technique

1992 • 248 citations

Regional changes in brain glucose metabolism reflect cognitive impairments in aged rats

1984 • 246 citations

Calcium concentration dynamics produced by synaptic activation of CA1 hippocampal pyramidal cells

1992 • 239 citations

Getting the message from the gene to the synapse: sorting and intracellular transport of RNA in neurons

1992 • 235 citations

Plasticity in the central nervous system: do synapses divide?

1983 • 231 citations

Signal enhancement in distal cortical dendrites by means of interactions between active dendritic spines.

1985 • 224 citations

Direct measurement of quantal changes underlying long-term potentiation in CA1 hippocampus

1992 • 218 citations

Spine density on neostriatal neurones changes with 6-hydroxydopamine lesions and with age

1989 • 215 citations

Changes in the numerical density of synaptic contacts with long‐term potentiation in the hippocampal dentate gyrus

1986 • 210 citations

Changes in the postsynaptic density with long‐term potentiation in the dentate gyrus

1986 • 206 citations

Direct relation of long-term synaptic potentiation to phosphorylation of membrane protein F1, a substrate for membrane protein kinase C

1986 • 201 citations

Differential subcellular localization of particular mRNAs in hippocampal neurons in culture

1990 • 201 citations

The synaptic organization of the caudate nucleus

1971 • 199 citations

Three-dimensional structure of dendritic spines in the rat neostriatum

1983 • 197 citations

Demonstration of local protein synthesis within dendrites using a new cell culture system that permits the isolation of living axons and dendrites from their cell bodies.

1992 • 197 citations

Spine Loss and Regrowth in Hippocampus following Deafferentation

1974 • 196 citations

Down's dyndrome and Alzheimer's disease: dendritic spine counts in the hippocampus

1990 • 194 citations

Evidence that protein constituents of postsynaptic membrane specializations are locally synthesized: analysis of proteins synthesized within synaptosomes

1991 • 191 citations

Increased NMDA responses and dendritic degeneration in human epileptic hippocampal neurons in slices

1991 • 182 citations

Dendritic reorganization in the denervated dentate gyrus of the rat following entorhinal cortical lesions: A Golgi and electron microscopic analysis

1983 • 178 citations

Calcium-induced long-term potentiation in the hippocampus

1982 • 170 citations

Dynamic changes in optic fiber terminal arbors lead to retinotopic map formation: An in vivo confocal microscopic study

1990 • 162 citations

Perforated postsynaptic densities: probable intermediates in synapse turnover.

1982 • 159 citations

An ultrastructural size principle

1994 • 155 citations

Dendritic spines: role of active membrane in modulating synaptic efficacy

1985 • 150 citations

Morphometric and dendritic analysis of fascia dentata granule cells in human aging and senile dementia

1987 • 145 citations

Synaptic remodelling during development and maturation: Junction differentiation and splitting as a mechanism for modifying connectivity

1984 • 142 citations

Pairing the cholinergic agonist carbachol with patterned Schaffer collateral stimulation initiates protein synthesis in hippocampal CA1 pyramidal cell dendrites via a muscarinic, NMDA-dependent mechanism

1993 • 141 citations

The role of Ca2+ entry via synaptically activated NMDA receptors in the induction of long-term potentiation

1993 • 140 citations

Kindling is associated with the formation of novel mossy fibre synapses in the CA3 region

1992 • 140 citations

mRNA at the synapse: analysis of a synaptosomal preparation enriched in hippocampal dendritic spines

1993 • 139 citations

Axonal arborization in the developing chick retinotectal system

1987 • 134 citations

The function of dendritic spines: A review of theoretical issues

1985 • 133 citations

Quantitative study on dendrites and dendritic spines in Alzheimer's disease and senile dementia.

1975 • 129 citations

Plasticity of the dendritic spine

1993 • 128 citations

N-type Ca2+ channels are located on somata, dendrites, and a subpopulation of dendritic spines on live hippocampal pyramidal neurons

1994 • 125 citations

Confocal microscopy: applications in neurobiology

1988 • 119 citations

Synaptic interface surface area increases with long-term potentiation in the hippocampal dentate gyrus

1988 • 117 citations

The Mechanism of Expression of Long-Term Enhancement of Hippocampal Synapses: Current Issues and Theoretical Implications

1993 • 116 citations

The development of pyramidal neurons after eye opening in the visual cortex of hooded rats: A quantitative study

1982 • 103 citations

Dendritic Spines: Convergence of Theory and Experiment

1992 • 95 citations

Methods of estimation of spine density--are spines evenly distributed throughout the dendritic field?

1991 • 87 citations

The formation of terminal fields in the absence of competitive interactions among primary motoneurons in the zebrafish

1990 • 82 citations

Organisation behaviour

1975 • 79 citations

Structural synaptic plasticity associated with the induction of long‐term potentiation is preserved in the dentate gyrus of aged rats

1992 • 78 citations

Confocal laser scanning microscopy reveals voltage‐gated calcium signals within hippocampal dendritic spines

1994 • 76 citations

Activity-dependent accumulation of calcium in Purkinje cell dendritic spines.

1988 • 71 citations

Dendritic Spines: Cellular Specializations Imparting Both Stability and Flexibility to Synaptic Function

1994 • 70 citations

Dendritic spines only connect

1981 • 69 citations

Redistribution of synaptic vesicles during long-term potentiation in the hippocampus

1987 • 67 citations

Is the function of dendritic spines to concentrate calcium?

1990 • 64 citations

TEA elicits two distinct potentiations of synaptic transmission in the CA1 region of the hippocampal slice

1994 • 62 citations

Structural Changes Accompanying Memory Storage

1993 • 62 citations

Protein synthesis and processing in cytoplasmic microdomains beneath postsynaptic sites on CNS neurons

1988 • 51 citations

Immunoreactive GAP-43 in the neuropil of adult rat neostriatum: Localization in unmyelinated fibers, axon terminals, and dendritic spines

1990 • 50 citations

The development of long-term potentiation in hippocampus and neocortex

1989 • 50 citations

Calcium-induced long-term potentiation in the hippocampal slice: Characterization of the time course and conditions

1986 • 49 citations

Protein kinase C mediates transient spinule-type neurite outgrowth in the retina during light adaptation.

1991 • 39 citations

Biochemical Correlates of Long-Term Potentiation in Hippocampal Synapses

1993 • 39 citations

Quantitative analysis of ultrastructural changes in synapses of the rat hippocampal field CA3 in vitro in different functional states

1986 • 38 citations

Mechanisms of synaptic plasticity

1991 • 36 citations

Ultrastructural effects of repetitive synaptic stimulation in the hippocampal slice preparation: A preliminary report

1979 • 35 citations

Persistence of individual dendritic spines in living brain slices

1992 • 34 citations

Quantification of dendritic spine populations using image analysis and a tilting disector

1995 • 34 citations

Presynaptic ultrastructural correlates of long-term potentiation in the CA1 subfield of the hippocampus

1990 • 28 citations

Astrocytic and synaptic response to kindling in hippocampal subfield CA1. I. Synaptogenesis in response to kindling in vitro

1993 • 27 citations

Block of induction and maintenance of calcium-induced LTP by inhibition of protein kinase C in postsynaptic neuron in hippocampal CA1 region

1994 • 23 citations

Estimation of the Size Distribution of Closed Cell Elements from Analysis of Their Random Plane Sections

1993 • 21 citations

Evidence that changes in spine neck resistance are not responsible for expression of LTP

1991 • 19 citations

Quantitative three‐dimensional confocal microscopy of synaptic structures in living brain tissue

1994 • 14 citations

Imaging of individual normal and regenerating optic fibers in the brain of living adult goldfish

1994 • 9 citations

Postnatal neuronal plasticity of the pyramidal cells of CA1 area of the hippocampus as a reaction to neurotoxic damage.

1991 • 2 citations

Deleted Work

1955 • 0 citations