The DNA methylation locusDDM1 is required for maintenance of gene silencing in Arabidopsis

Genomic sequencing.

1984 • 8,343 citations

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

1992 • 3,907 citations

A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands.

1992 • 3,099 citations

Cytosine methylation and the ecology of intragenomic parasites

1997 • 1,906 citations

DNA Modification Mechanisms and Gene Activity During Development

1975 • 1,859 citations

A procedure for mapping Arabidopsis mutations using co‐dominant ecotype‐specific PCR‐based markers

1993 • 1,574 citations

X inactivation, differentiation, and DNA methylation

1975 • 1,283 citations

A Similarity Between Viral Defense and Gene Silencing in Plants

1997 • 821 citations

Reduced DNA methylation in Arabidopsis thaliana results in abnormal plant development.

1996 • 705 citations

Modifiers of position effect are shared between telomeric and silent mating-type loci in S. cerevisiae

1991 • 700 citations

Arabidopsis thaliana DNA Methylation Mutants

1993 • 674 citations

How does DNA methylation repress transcription?

1997 • 532 citations

Expansions of transgene repeats cause heterochromatin formation and gene silencing in Drosophila

1994 • 506 citations

Position effect variegation in Drosophila is associated with an altered chromatin structure.

1995 • 475 citations

Demethylation-Induced Developmental Pleiotropy in Arabidopsis

1996 • 450 citations

Effect of site-specific modification on restriction endonucleases and DNA modification methyltransferases

1994 • 439 citations

Hypermethylated SUPERMAN Epigenetic Alleles in Arabidopsis

1997 • 428 citations

Perturbation of Nuclear Architecture by Long-Distance Chromosome Interactions

1996 • 425 citations

Developmental abnormalities and epimutations associated with DNA hypomethylation mutations.

1996 • 371 citations

The somatic replication of DNA methylation

1981 • 368 citations

HOMOLOGY-DEPENDENT GENE SILENCING IN PLANTS

1996 • 342 citations

Position effect variegation at fission yeast centromeres

1994 • 332 citations

Epigenetic inheritance of transcriptional states in S. cerevisiae

1989 • 327 citations

RNA-Mediated RNA Degradation and Chalcone Synthase A Silencing in Petunia

1997 • 308 citations

Differential expression of a new dominant agouti allele (Aiapy) is correlated with methylation state and is influenced by parental lineage.

1994 • 270 citations

Chromosomal Inheritance of Epigenetic States in Fission Yeast During Mitosis and Meiosis

1996 • 258 citations

Cosuppression in Drosophila: Gene Silencing of Alcohol dehydrogenase by white-Adh Transgenes Is Polycomb Dependent

1997 • 245 citations

Epigenetic control of an endogenous gene family is revealed by a novel blue fluorescent mutant of arabidopsis

1995 • 242 citations

Post-transcriptional gene silencing in plants

1997 • 241 citations

Gating of epidermal plasmodesmata is restricted to the leading edge of expanding infection sites of tobacco mosaic virus (TMV)

1997 • 223 citations

Differences in DNA‐methylation are associated with a paramutation phenomenon in transgenic petunia

1993 • 219 citations

Molecular mechanisms in the developmental regulation of the maize Suppressor-mutator transposable element.

1988 • 207 citations

Duplications That Suppress and Deletions That Restore Expression from a Chalcone Synthase Multigene Family.

1996 • 205 citations

Evidence for cytosine methylation of non-symmetrical sequences in transgenic Petunia hybrida.

1994 • 193 citations

DNA methylation and plant development

1997 • 185 citations

Tryptophan-Requiring Mutants of the Plant Arabidopsis thaliana

1988 • 172 citations

Genomic Imprinting in Plants: Parental Effects and Trans-Inactivation Phenomena

1993 • 168 citations

Release of epigenetic gene silencing by trans-acting mutations in Arabidopsis

1998 • 157 citations

Paramutation, an allelic interaction, is associated with a stable and heritable reduction of transcription of the maize b regulatory gene.

1993 • 155 citations

Somatically heritable switches in the DNA modification of Mu transposable elements monitored with a suppressible mutant in maize.

1990 • 151 citations

Pl-Bh, an anthocyanin regulatory gene of maize that leads to variegated pigmentation.

1993 • 138 citations

Chromatin-silencing mechanisms in Drosophila maintain patterns of gene expression

1997 • 137 citations

Characterization of anArabidopsis thalianaDNA hypomethylation mutant

1995 • 129 citations

RIGS (repeat-induced gene silencing) in Arabidopsis is transcriptional and alters chromatin configuration.

1996 • 126 citations

DNA methylation in eukaryotes

1995 • 121 citations

Allelic interactions heritably alter the activity of a metastable maize pl allele.

1995 • 121 citations

Coordinate suppression of mutations caused by Robertson's mutator transposons in maize.

1994 • 117 citations

Variegated phenotype and developmental methylation changes of a maize allele originating from epimutation.

1994 • 109 citations

Epigenetic phenomena: Epigenetic phenomena: Paramutation and gene silencing in plants

1996 • 91 citations

Organization of paramutagenicity in R-stippled maize.

1995 • 86 citations

Characterization of Post-Transcriptionally Suppressed Transgene Expression That Confers Resistance to Tobacco Etch Virus Infection in Tobacco.

1997 • 79 citations

In vitro DNA methylation inhibits gene expression in transgenic tobacco.

1990 • 73 citations

Cytosine Methylation Associated With Repeat-Induced Point Mutation Causes Epigenetic Gene Silencing in Neurospora crassa

1997 • 73 citations

The reduced expression of endogenous duplications (REED) in the maize R gene family is mediated by DNA methylation.

1995 • 67 citations

Allelic interactions at the nivea locus of Antirrhinum.

1991 • 67 citations

An uncertain silence

1997 • 65 citations

Arabidopsis phosphoribosylanthranilate isomerase: molecular genetic analysis of triplicate tryptophan pathway genes.

1995 • 60 citations

^mCCG methylation in angiosperms

1996 • 51 citations

Transient expression in Arabidopsis thaliana protoplasts derived from rapidly established cell suspension cultures

1993 • 50 citations

Genetics of homology‐dependent gene silencing in Arabidopsis; a role for methylation

1997 • 48 citations

Isolation of the Ascobolus immersus spore color gene b2 and study in single cells of gene silencing by methylation induced premeiotically.

1995 • 22 citations