The mitochondrial toxin 3‐nitropropionic acid induces differential expression patterns of apoptosis‐related markers in rat striatum

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A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes

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Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid

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Immunohistochemical determination of in vivo distribution of Bax, a dominant inhibitor of Bcl-2.

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Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models

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bcl-2 protein expression is widespread in the developing nervous system and retained in the adult PNS

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1995 • 350 citations

Mechanisms of Cell Death Induced by the Mitochondrial Toxin 3-Nitropropionic Acid: Acute Excitotoxic Necrosis and Delayed Apoptosis

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Nature and distribution of brain lesions in rats intoxicated with 3-nitropropionic acid: A type of hypoxic (energy deficient) brain damage

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3-Nitropropionic acidʼs lethal triplet

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Bax expression in mammalian neurons undergoing apoptosis, and in Alzheimer's disease hippocampus

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Apoptosis and expression of p53 response proteins and cyclin D1 after cortical impact in rat brain

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Differential Regulation of Bax, Bcl‐2, and Bcl‐X Proteins in Focal Cortical Ischemia in the Rat

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Excitotoxicity is Required for Induction of Oxidative Stress and Apoptosis in Mouse Striatum by the Mitochondrial Toxin, 3-Nitropropionic Acid

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3-Nitropropionic acid induces apoptosis in cultured striatal and cortical neurons

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A novel effect of nicotine on mood and sleep in major depression

1998 • 108 citations

Alterations of Bcl-2 family proteins precede cytoskeletal proteolysis in the penumbra, but not in infarct centres following focal cerebral ischemia in mice

1998 • 72 citations

Metabolic Compromise with Systemic 3-Nitropropionic Acid Produces Striatal Apoptosis in Sprague–Dawley Rats but Not in BALB/c ByJ Mice

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Apoptotic DNA fragmentation and upregulation of Bax induced by transient ischemia of the rat retina

1999 • 68 citations

3‐Nitropropionic acid induces a spectrum of Huntington’s disease‐like neuropathology in rat striatum

1999 • 66 citations

N‐Methyl‐<scp>d</scp>‐Aspartate Receptor Desensitisation Is Neuroprotective by Inhibiting Glutamate‐Induced Apoptotic‐Like Death

1998 • 61 citations

Apoptosis in the striatum of rats following intraperitoneal injection of 3-nitropropionic acid

1997 • 51 citations

Evidence of apoptosis in primary neuronal cultures after heat shock

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ATP Deficits and Neuronal Degeneration Induced by 3‐Nitropropionic Acid

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Bcl-2, Bax, and Bcl-x expression in the CA1 area of the hippocampus following transient forebrain ischemia in the adult gerbil

1998 • 46 citations

Decreased expression of bcl-2 and bcl-x mRNA coincides with apoptosis following intracerebral administration of 3-nitropropionic acid

1998 • 27 citations

3-Nitropropionic acid induces poly(ADP-ribosyl)ation and apoptosis related gene expression in the striatum in vivo

1997 • 26 citations

Alteration ofbcl-2 andbax expression in embolized meningiomas

1998 • 8 citations

Postnatal changes in Bax-immunoreactivity and apoptosis of the rat trigeminal primary neurons

1998 • 7 citations