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Dynasore, a Cell-Permeable Inhibitor of Dynamin

Data up to Jan 2025

Published2006
Citations1,905
References54

Total Citations Per Year

Abstract

References (54)

The dynamin superfamily: universal membrane tubulation and fission molecules?

2004 • 1,329 citations

Induction of mutant dynamin specifically blocks endocytic coated vesicle formation.

1994 • 1,206 citations

Endocytosis by Random Initiation and Stabilization of Clathrin-Coated Pits

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Dynamin-mediated Internalization of Caveolae

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Caveolae/raft-dependent endocytosis

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Imaging actin and dynamin recruitment during invagination of single clathrin-coated pits

2002 • 695 citations

Dynamin Undergoes a GTP-Dependent Conformational Change Causing Vesiculation

1998 • 665 citations

Dynamin at the Neck of Caveolae Mediates Their Budding to Form Transport Vesicles by GTP-driven Fission from the Plasma Membrane of Endothelium

1998 • 657 citations

Microtubule-induced focal adhesion disassembly is mediated by dynamin and focal adhesion kinase

2005 • 612 citations

The GTPase dynamin binds to and is activated by a subset of SH3 domains

1993 • 557 citations

GTPase activity of dynamin and resulting conformation change are essential for endocytosis

2001 • 451 citations

Disappearance and reformation of synaptic vesicle membrane upon transmitter release observed under reversible blockage of membrane retrieval

1989 • 442 citations

Clathrin-independent pinocytosis is induced in cells overexpressing a temperature-sensitive mutant of dynamin.

1995 • 400 citations

Caveosomes and endocytosis of lipid rafts

2003 • 386 citations

Internalization of cholera toxin by different endocytic mechanisms

2001 • 383 citations

Nucleotide-dependent conformational changes in dynamin: evidence for a mechanochemical molecular spring

1999 • 380 citations

Reversible blockage of membrane retrieval and endocytosis in the garland cell of the temperature-sensitive mutant of Drosophila melanogaster, shibirets1.

1983 • 332 citations

SH3-domain-containing proteins function at distinct steps in clathrin-coated vesicle formation

1999 • 275 citations

Three-dimensional reconstruction of dynamin in the constricted state

2001 • 243 citations

Dynamin at the actin–membrane interface

2003 • 241 citations

Dynamin:Gtp Controls the Formation of Constricted Coated Pits, the Rate Limiting Step in Clathrin-Mediated Endocytosis

2000 • 232 citations

Garrotes, Springs, Ratchets, and Whips: Putting Dynamin Models to the Test

2000 • 215 citations

Redundant and Distinct Functions for Dynamin-1 and Dynamin-2 Isoforms

1998 • 208 citations

Dynamin family of mechanoenzymes

2001 • 197 citations

Kinetics of transit of transferrin and epidermal growth factor through clathrin-coated membranes

1984 • 174 citations

Dynamin GTPase Domain Mutants Block Endocytic Vesicle Formation at Morphologically Distinct Stages

2001 • 173 citations

Dynamin

1998 • 172 citations

Real-time analysis of clathrin-mediated endocytosis during cell migration

2003 • 171 citations

A Robotics-Based Automated Assay for Inorganic and Organic Phosphates

1999 • 170 citations

Actin and Arf1-dependent recruitment of a cortactin–dynamin complex to the Golgi regulates post-Golgi transport

2005 • 167 citations

Clathrin‐ and Dynamin‐Dependent Coated Vesicle Formation from Isolated Plasma Membranes

2003 • 160 citations

Characterization of rhoGAP. A GTPase-activating protein for rho-related small GTPases.

1994 • 159 citations

The stalk region of dynamin drives the constriction of dynamin tubes

2004 • 155 citations

Rapid constriction of lipid bilayers by the mechanochemical enzyme dynamin

2004 • 150 citations

Interferon-induced human protein MxA is a GTPase which binds transiently to cellular proteins

1992 • 145 citations

Modulation of Rac Localization and Function by Dynamin

2003 • 139 citations

Epidermal Growth Factor Receptor Internalization through Clathrin-Coated Pits Requires Cbl RING Finger and Proline-Rich Domains But Not Receptor Polyubiquitylation

2003 • 139 citations

Dynamin and endocytosis

2002 • 128 citations

The Role of Dynamin and Its Binding Partners in Coated Pit Invagination and Scission

2001 • 127 citations

Synergistic Activation of Dynamin GTPase by Grb2 and Phosphoinositides

1998 • 126 citations

A Molecular Motor or a Regulator? Dynamin's in a Class of Its Own

2003 • 119 citations

A Sensitive Assay for Phosphoinositide Phosphatases

2000 • 117 citations

[24] Tightly regulated and inducible expression of dominant interfering dynamin mutant in stably transformed HeLa cells

1995 • 109 citations

Cholera Toxin Toxicity Does Not Require Functional Arf6- and Dynamin-dependent Endocytic Pathways

2004 • 96 citations

Dynamin GTPase Domain Mutants That Differentially Affect GTP Binding, GTP Hydrolysis, and Clathrin-mediated Endocytosis

2004 • 93 citations

Self-assembly of Human MxA GTPase into Highly Ordered Dynamin-like Oligomers

2002 • 91 citations

Interferon-induced MxA Protein.

1995 • 71 citations

An internal GAP domain negatively regulates presynaptic dynamin in vivo

2005 • 64 citations

Oligomerization and kinetic mechanism of the dynamin GTPase

2002 • 34 citations

Cell-free Transport from the trans-Golgi Network to Late Endosome Requires Factors Involved in Formation and Consumption of Clathrin-coated Vesicles

2004 • 29 citations

Mixed-lineage kinase 2-SH3 domain binds dynamin and greatly enhances activation of GTPase by phospholipid

1998 • 28 citations

Endocytosis: Is dynamin a ‘blue collar’ or ‘white collar’ worker?

1999 • 24 citations

Possible role of deep tubular invaginations of the plasma membrane in MHC-I trafficking

2005 • 20 citations

Forthcoming papers and review topics

2003 • 17 citations

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Dynasore, a Cell-Permeable Inhibitor of Dynamin (2006) – Developmental Cell | Metascience Observatory Explorer