Quantifying the Role of Angiogenesis in Malignant Progression of Gliomas: In Silico Modeling Integrates Imaging and Histology

The 2007 WHO Classification of Tumours of the Central Nervous System

2007 • 13,561 citations

The 2007 WHO classification of tumours of the central nervous system

2007 • 4,330 citations

WHO classification of tumours of the central nervous system

2007 • 3,749 citations

Virtual and real brain tumors: using mathematical modeling to quantify glioma growth and invasion

2003 • 560 citations

Continuous growth of mean tumor diameter in a subset of grade II gliomas

2003 • 472 citations

Vascular endothelial growth factor and glioma angiogenesis: Coordinate induction of VEGF receptors, distribution of VEGF protein and possibleIn vivo regulatory mechanisms

1994 • 464 citations

Models of epidermal wound healing

1990 • 398 citations

Angiogenesis in Gliomas: Biology and Molecular Pathophysiology

2005 • 340 citations

Modeling the early stages of vascular network assembly

2003 • 325 citations

The Evolution of Mathematical Modeling of Glioma Proliferation and Invasion

2007 • 308 citations

Predicting the efficacy of radiotherapy in individual glioblastoma patientsin vivo:a mathematical modeling approach

2010 • 274 citations

A mathematical modelling tool for predicting survival of individual patients following resection of glioblastoma: a proof of principle

2007 • 273 citations

Mathematical Modeling of Capillary Formation and Development in Tumor Angiogenesis: Penetration into the Stroma

2001 • 265 citations

Virtual brain tumours (gliomas) enhance the reality of medical imaging and highlight inadequacies of current therapy

2002 • 250 citations

Growth factors in glioma angiogenesis: FGFs, PDGF, EGF, and TGFs.

2000 • 238 citations

Prognostic value of initial magnetic resonance imaging growth rates for World Health Organization grade II gliomas

2006 • 234 citations

Prognostic Significance of Growth Kinetics in Newly Diagnosed Glioblastomas Revealed by Combining Serial Imaging with a Novel Biomathematical Model

2009 • 232 citations

Quantitative Metrics of Net Proliferation and Invasion Link Biological Aggressiveness Assessed by MRI with Hypoxia Assessed by FMISO-PET in Newly Diagnosed Glioblastomas

2009 • 152 citations

Different angiogenic phenotypes in primary and secondary glioblastomas

2005 • 138 citations

Complementary but Distinct Roles for MRI and¹⁸F-Fluoromisonidazole PET in the Assessment of Human Glioblastomas

2008 • 137 citations

Hypoxia‐regulated protein expression, patient characteristics, and preoperative imaging as predictors of survival in adults with glioblastoma multiforme

2008 • 129 citations

Quantifying efficacy of chemotherapy of brain tumors with homogeneous and heterogeneous drug delivery.

2002 • 119 citations

The Role of Vascular Proliferation in the Growth of Brain Tumors

1976 • 118 citations

Hypoxia‐inducible factor 1α/vascular endothelial growth factor axis in astrocytomas. Associations with microvessel morphometry, proliferation and prognosis

2004 • 92 citations

The extent of intracranial gliomata at autopsy and its relationship to techniques used in radiation therapy of brain tumors.

1960 • 81 citations

Matrix metalloproteinase 2 (MMP-2) immunoreactive protein is associated with poor grade and survival in brain neoplasms.

2000 • 77 citations

The Role of Transforming Growth Factor-β–Mediated Tumor-Stroma Interactions in Prostate Cancer Progression: An Integrative Approach

2009 • 64 citations

Velocity of Radial Expansion of Contrast-enhancing Gliomas and the Effectiveness of Radiotherapy in Individual Patients: a Proof of Principle

2008 • 63 citations

Virtual resection of gliomas: Effect of extent of resection on recurrence

2003 • 60 citations

Applying a patient-specific bio-mathematical model of glioma growth to develop virtual [18F]-FMISO-PET images

2011 • 50 citations

Spatial expression of VEGF-A in human glioma.

2002 • 36 citations

Evaluation of intratumoral administration of tumor necrosis factor-alpha in patients with malignant glioma.

2007 • 27 citations

Expression of nestin and vimentin in gliomatosis cerebri

2006 • 16 citations

Measurement of Endothelial Cell Proliferation Rate in vivo Using 2H2O Labeling: A Kinetics Biomaker of Angiogenesis

2006 • 7 citations