Immune Responses to Myelin Antigens in Multiple Sclerosis^a

Clinical diagnosis and management by laboratory methods

1979 • 1,701 citations

Cell-type-specific markers for distinguishing and studying neurons and the major classes of glial cells in culture

1979 • 805 citations

Isolation of myelin basic protein-reactive T-cell lines from normal human blood

1983 • 270 citations

The Application of Tissue Culture to the Study of Experimental “Allergic” Encephalomyelitis*

1961 • 246 citations

Experimental Allergic Neuritis Induced by Sensitization with Galactocerebroside

1979 • 212 citations

Autoimmunity: Genetic, Immunologic, Virologic, and Clinical Aspects

1978 • 187 citations

Complement activation by isolated myelin: activation of the classical pathway in the absence of myelin-specific antibodies.

1982 • 160 citations

Antibodies to Oligodendroglia in Patients with Multiple Sclerosis

1977 • 159 citations

T lymphocyte lines producing or vaccinating against autoimmune encephalomyelitis (EAE). Functional activation induces peanut agglutinin receptors and accumulation in the brain and thymus of line cells

1983 • 145 citations

CSF Antibody to Myelin Basic Protein

1980 • 144 citations

Comparison between directional Doppler and angiography in the diagnosis of internal carotid artery disease

2009 • 143 citations

In Vitro Cell-Mediated Immunity of Cerebrospinal-Fluid Lymphocytes to Myelin Basic Protein in Primary Demyelinating Diseases

1977 • 142 citations

CIRCULATING IMMUNE COMPLEXES IN MULTIPLE SCLEROSIS AND OTHER NEUROLOGICAL DISEASES

1976 • 141 citations

The Guillain-Barré Syndrome and Multiple Sclerosis

1971 • 140 citations

TISSUE CULTURE STUDIES OF DEMYELINATION^*

1965 • 137 citations

Functional Studies of Cultured Brain Tissues as Related to "Demyelinative Disorders"

1965 • 135 citations

Cell type-specific markers for human glial and neuronal cells in culture.

1980 • 135 citations

The in vitro demyelinating activity of sera from guinea pigs sensitized with whole CNS and with purified encephalitogen

1968 • 115 citations

Abnormal T cell subpopulations and circulating immune complexes in the Guillain‐Barré syndrome and multiple sclerosis

1978 • 112 citations

Binding of normal human IgG to myelin sheaths, glia and neurons.

1975 • 107 citations

Anti-ganglioside antibodies in multiple sclerosis

1980 • 105 citations

Antimyelin Antibodies in Neurologic Diseases

1975 • 95 citations

Lithium treatment: does the kidney prefer one daily dose instead of two?

1982 • 93 citations

Disseminated vasculomyelinopathy: An immune complex disease

1980 • 93 citations

The Assessment by Immunofluorescence Methods of Humoral Anti-Myelin Antibodies in Man

1970 • 86 citations

Cell‐mediated immunity to myelin basic protein in acute disseminated encephalomyelitis

1974 • 85 citations

Multiple sclerosis

1980 • 81 citations

Multiple specificities of antibrain antibodies in multiple sclerosis and chronic myelopathy

1978 • 80 citations

IMMUNOPATHOLOGY OF DEMYELINATION IN AUTOIMMUNE DISEASES AND VIRUS INFECTIONS

1977 • 79 citations

Tissue culture studies of demyelinating disease: A critical review

1977 • 70 citations

Spinal Fluid Differences in Experimental Allergic Encephalomyelitis and Multiple Sclerosis

1978 • 63 citations

Oligodendrocyte staining by multiple sclerosis serum is nonspecific

1979 • 63 citations

Serological techniques for detection of antibody to galactocerebroside

1976 • 61 citations

Multiple Sclerosis: Serum Factor Producing Reversible Alterations in Bioelectric Responses

1966 • 55 citations

Search for anti‐encephalitogen antibody in human demyelinative diseases

1968 • 54 citations

Neural cell markers and their applications to neurology

1982 • 51 citations

CSF antibodies to myelin basic protein and oligodendrocytes in multiple sclerosis and other neurological diseases

2009 • 47 citations

Myelin basic protein antibodies in the serum and CSF of multiple sclerosis and subacute sclerosing panencephalitis patients

2009 • 46 citations

MULTIPLE SCLEROSIS: A VIRUS DISEASE?

1977 • 45 citations

DEMONSTRATION IN TISSUE CULTURE OF MYELINOTOXICITY IN CEREBROSPINAL FLUID AND BRAIN EXTRACTS FROM MULTIPLE SCLEROSIS PATIENTS

1970 • 45 citations

Gamma-Globulin Affinity for Normal Human Tissue of the Central Nervous System

1964 • 44 citations

Cultured human and rat oligodendrocytes and rat schwann cells do not have immune response gene associated antigen (Ia) on their surface

1983 • 44 citations

Myelin-binding antibodies in vitro. Immunoperoxidase studies with experimental allergic encephalomyelitis, anti-galactocerebroside and multiple sclerosis sera

1978 • 43 citations

Sphingolipid Antibodies in Sera of Animals and Patients with Central Nervous System Lesions.

1962 • 43 citations

EFFECT OF MONONUCLEAR BLOOD CELLS FROM MULTIPLE SCLEROSIS PATIENTS OX NEUROGLIA IN TISSUE CULTURE

1964 • 42 citations

Cellular-Immune Response to Myelin Protein: Absence in Multiple Sclerosis and Presence in Cerebrovascular Accidents*

1974 • 42 citations

Binding of 125 I myelin basic protein by serum and cerebrospinal fluid.

1972 • 41 citations

Serological reactions against glycolipid-sensitised liposomes in multiple sclerosis

1976 • 36 citations

Multiple sclerosis serum and cerebrospinal fluid immunoglobulin binding to fc receptors of oligodendrocytes

1981 • 36 citations

Multiple sclerosis: Circulating antigen‐reactive lymphocytes

1979 • 33 citations

Immunologic characterization of cerebrospinal fluid lymphocytes: Preliminary report

1976 • 32 citations

Antibodies to Glycosphingolipids in Patients with Multiple Sclerosis and SLE

1984 • 32 citations

Multiple Sclerosis Cerebrospinal Fluid Produces Myelin Lesions in Tadpole Optic Nerves

1976 • 32 citations

Antibodies to viral and non-viral antigens in subacute sclerosing panencephalitis and multiple sclerosis demonstrated by thin-layer polyacrylamide gel isoelectric focusing, antigen immunofixation and autoradiography

1981 • 31 citations

Antioligodendrocyte antibodies in cerebrospinal fluid of multiple sclerosis and other neurologic diseases

1981 • 29 citations

Serum 19S and 7S demyelinating antibodies in multiple sclerosis.

1968 • 29 citations

Antibody-dependent lymphocyte cytotoxicity against basic protein of myelin in multiple sclerosis

1980 • 29 citations

Neuroelectric Blocking Factors in Multiple Sclerosis and Normal Human Sera

1976 • 29 citations

A search for antibodies against glial cells in the serum and cerebrospinal fluid of patients with multiple sclerosis and Guillain-Barré syndrome

1979 • 27 citations

Complement‐dependent serum

1978 • 26 citations

Cell‐mediated immunity to measles, myelin basic protein, and central nervous system extract in multiple sclerosis

1978 • 26 citations

Partial purification of MS specific brain antigens

2009 • 25 citations

E rosette-forming lymphocytes in multiple sclerosis patients. Basic protein stimulation of rosette-forming cells

2009 • 22 citations

Stimulation of active E-rosette forming lymphocytes by myelin basic protein and specific antigens from multiple sclerosis brains

1979 • 22 citations

EFFECT OF ENCEPHALITOGENIC PROTEIN ON MIGRATION IN AGAROSE OF LEUKOCYTES FROM PATIENTS WITH MULTIPLE SCLEROSIS

1977 • 21 citations

Oligodendrocyte‐binding antibodies in multiple sclerosis

1980 • 21 citations

Depression of complex bioelectric discharges in cerebral tissue cultures by thermolabile complement-dependent serum factors

1975 • 20 citations

Specificity of antibody-dependent lymphocyte cytotoxicity against cerebral tissue constituents in multiple sclerosis

1982 • 20 citations

EFFECT OF BASIC ENCEPHALITOGENIC PROTEIN AND SOME PEPTIDES DERIVED FROM IT ON THE MIGRATION IN AGAROSE GEL OF LEUKOCYTES FROM PATIENTS WITH MULTIPLE SCLEROSIS, OTHER NEUROLOGICAL DISEASES, OR CARCINOMA

2009 • 20 citations

Lymphocyte transformation in the presence of myelin basic protein in multiple sclerosis and control subjects

2009 • 19 citations

Long-term growthin vitro of human cerebrospinal fluid T lymphocytes

1981 • 19 citations

Generation and biological properties of a monoclonal antibody to Galactocerebroside

1984 • 17 citations

Myelin basic protein binding cells in active multiple sclerosis

1979 • 17 citations

Circulating antibody to myelin basic protein in relapsing-remitting multiple sclerosis? A comparative group and sequential study by radioimmunoassay.

1978 • 15 citations

Proliferation of multiple sclerosis cerebrospinal fluid lymphocytes after stimulation with measles virus antigens

2009 • 14 citations

Do patients with demyelinating disease have antibodies against human glial cells in their sera?

1981 • 14 citations

Spinal fluid basic protein immunoreactive material and spinal fluid lymphocyte reactivity to basic protein

1981 • 14 citations

Sensitization of cerebrospinal fluid and peripheral blood lymphocytes to myelin basic protein in multiple sclerosis

2009 • 14 citations

145 HELPER ANTIGENS ARE NEEDED FOR DEMYELINATION

1980 • 13 citations

A microtechnique for PHA transformation of 5000 separated lymphocytes

1974 • 12 citations

Studies of cellular sensitization to myelin antigens in multiple sclerosis

1977 • 12 citations

Antigenic stimulation of active E-rosette-forming lymphocytes in multiple sclerosis, systemic lupus erythematosus, and rheumatoid arthritis

1980 • 10 citations

Antibodies to Glycosphingolipids in Patients with Multiple Sclerosis^a

1984 • 10 citations

LEUKOCYTE MIGRATION IN AGAROSE, A STUDY ON MULTIPLE SCLEROSIS

1975 • 9 citations

GALACTOCEREBROSIDE ANTIBODY LEVELS IN MULTIPLE SCLEROSIS

2009 • 7 citations

Search for a multiple sclerosis‐specific brain antigen

1983 • 7 citations

A new assay for lytic anti-galactocerebroside (GC) antibodies employing 56rubidium release from GC-labelled liposomes

1980 • 5 citations

Hyperreactivity to myelin basic protein in multiple sclerosis

1981 • 4 citations

Cytotoxic Cells in Peripheral Blood and Cerebrospinal Fluid of Multiple Sclerosis Patients

1984 • 3 citations

First international congress of neuroimmunology

1982 • 2 citations

Deleted Work

1955 • 0 citations