Chronic Exposure to the Carcinogenic Compound Benzo[a]Pyrene Induces Larger and Phenotypically Different Atherosclerotic Plaques in ApoE-Knockout Mice
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References (44)
Atherosclerosis — An Inflammatory Disease
1999 • 21,494 citations
The cardiovascular health study: Design and rationale
1991 • 3,584 citations
A Definition of Advanced Types of Atherosclerotic Lesions and a Histological Classification of Atherosclerosis
1995 • 3,361 citations
Atherosclerosis: Basic Mechanisms
1995 • 1,697 citations
ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree.
1994 • 1,646 citations
A Definition of Advanced Types of Atherosclerotic Lesions and a Histological Classification of Atherosclerosis
1995 • 933 citations
Evidence for a Monoclonal Origin of Human Atherosclerotic Plaques
1973 • 900 citations
Immune Mechanisms in Atherosclerosis
2001 • 852 citations
Immune mechanisms in atherosclerosis.
1989 • 827 citations
Cigarette Smoking and Progression of Atherosclerosis
1998 • 724 citations
Elevated Levels of Oxidative DNA Damage and DNA Repair Enzymes in Human Atherosclerotic Plaques
2002 • 420 citations
Polynuclear aromatic compounds, Part 1, Chemical, environmental and experimental data.
1983 • 285 citations
The absence of p53 accelerates atherosclerosis by increasing cell proliferation in vivo
1999 • 278 citations
Evidence for a local immune response in atherosclerosis. CD4+ T cells infiltrate lesions of apolipoprotein-E-deficient mice.
1996 • 249 citations
Atherosclerosis and Cancer
2001 • 226 citations
Polycyclic aromatic hydrocarbons in Dutch total diet samples (1984–1986)
1990 • 202 citations
Active and passive smoking are associated with increased carotid wall thickness. The Atherosclerosis Risk in Communities Study
1994 • 198 citations
DNA adducts and chronic degenerative disease. Pathogenetic relevance and implications in preventive medicine.
1996 • 163 citations
Molecular epidemiology of atherosclerosis
1997 • 162 citations
Macrophage p53 Deficiency Leads to Enhanced Atherosclerosis in APOE*3-Leiden Transgenic Mice
2001 • 160 citations
Relation of smoking with carotid artery wall thickness and stenosis in older adults. The Cardiovascular Health Study. The Cardiovascular Health Study (CHS) Collaborative Research Group.
1994 • 148 citations
Putative susceptibility markers of coronary artery disease: association between VDR genotype, smoking, and aromatic DNA adduct levels in human right atrial tissue
1998 • 148 citations
Transforming gene in human atherosclerotic plaque DNA.
1986 • 139 citations
Active and Passive Smoking Are Associated With Increased Carotid Wall Thickness
1994 • 139 citations
DNA adducts and chronic degenerative diseases. Pathogenetic relevance and implications in preventive medicine
1996 • 135 citations
Arteriosclerotic plaque development is ‘promoted’ by polynuclear aromatic hydrocarbons
1988 • 129 citations
Effect of carcinogens on chicken atherosclerosis.
1977 • 129 citations
Mouse models of hyperlipidemia and atherosclerosis
2001 • 116 citations
Differences in aromatic-DNA adduct levels between alveolar macrophages and subpopulations of white blood cells from smokers
1998 • 107 citations
Direct suppression of in vitro antibody production by mouse spleen cells by the carcinogen benzo(a)pyrene but not by the noncarcinogenic congener benzo(e)pyrene.
1984 • 87 citations
Detection of immunotoxicity of benzo[a]pyrene in a subacute toxicity study after oral exposure in rats
1999 • 82 citations
Analysis of human exposure to benzo(a)pyrene via inhalation and food ingestion in the Total Human Environmental Exposure Study (THEES).
1991 • 78 citations
Further investigations of the capacity of polynuclear aromatic hydrocarbons to elicit atherosclerotic lesions
1981 • 59 citations
Dose-dependent size increases of aortic lesions following chronic exposure to 7,12-dimethylbenz(a)anthracene.
1981 • 55 citations
Cancer biomarkers in human atherosclerotic lesions: detection of DNA adducts.
1995 • 55 citations
Formation of DNA adducts in the aorta of smoke-exposed rats, and modulation by chemopreventive agents
2001 • 33 citations
Animal studies suggesting involvement of mutagen/carcinogen exposure in atherosclerosis
1990 • 31 citations
Comparison of 32P-postlabeling and HPLC-FD analysis of DNA adducts in rats acutely exposed to benzo(a)pyrene
1997 • 27 citations
DNA adducts and human atherosclerotic lesions
2001 • 27 citations
Compensatory Enlargement and Stenosis Develop in ApoE −/− and ApoE*3-Leiden Transgenic Mice
2001 • 26 citations
Cancer biomarkers in human atherosclerotic lesions: no evidence of p53 involvement.
1995 • 25 citations
Effects of polycyclic aromatic hydrocarbons on proliferation, collagen secretion and viability of arterial smooth muscle cells in culture.
1988 • 25 citations
An ultrastructural comparison of carcinogen-associated and spontaneous aortic lesions in the cockerel.
1984 • 24 citations
Inventory and biological impact of polycyclic carcinogens in the environment
1983 • 9 citations
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