Effect of enzyme induction on the metabolism and tissue distribution of benzo(alpha)pyrene.

A simple efficient liquid scintillator for counting aqueous solutions in a liquid scintillation counter

1960 • 7,610 citations

Pharmacological implications of microsomal enzyme induction.

1967 • 2,883 citations

Mammary Cancer Induced by a Single Feeding of Polynuclear Hydrocarbons, and its Suppression

1961 • 788 citations

Adaptive increases in drug-metabolizing enzymes induced by phenobarbital and other drugs.

1960 • 511 citations

Substrate-Induced Synthesis And Other Properties Of Benzpyrene Hydroxylase In Rat Liver

1957 • 475 citations

The metabolism of methylated aminoazo dyes. V. Evidence for induction of enzyme synthesis in the rat by 3-methylcholanthrene.

1956 • 393 citations

A microsome-dependent binding of benzo[a]pyrene to DNA.

1969 • 332 citations

Benzpyrene hydroxylase activity in the gastrointestinal tract.

1962 • 328 citations

HISTOCHEMICAL DEMONSTRATION OF REDUCED PYRIDINE NUCLEOTIDE DEPENDENT POLYCYCLIC HYDROCARBON METABOLIZING SYSTEMS

1962 • 210 citations

SELECTIVE ADRENAL NECROSIS AND APOPLEXY INDUCED BY 7,12-DIMETHYLBENZ(a)ANTHRACENE

1961 • 181 citations

On the protective action of certain polycyclic aromatic hydrocarbons against carcinogenesis by aminoazo dyes and 2-acetylaminofluorene.

1958 • 180 citations

Aryl hydrocarbon hydroxylase activity in human placenta from cigarette smoking and nonsmoking women.

1969 • 170 citations

Stimulatory effect of cigarette smoking on the hydroxylation of 3,4‐benzpyrene and the N‐demethylation of 3‐methyl‐4‐monomethylaminoazobenzene by enzymes in human placenta

1969 • 168 citations

Induction of Microsomal Enzyme Synthesis by Polycyclic Aromatic Hydrocarbons of Different Molecular Sizes

1961 • 166 citations

Induction of increased benzpyrene hydroxylase activity by flavones and related compounds.

1968 • 142 citations

ENZYMATIC HYDROXYLATION OF BENZOPYRENE AND ITS RELATIONSHIP TO CYTOTOXICITY

1969 • 136 citations

Liver tumor inhibition and adrenal histologic responses in rats to which 3'-methyl-4-dimethylaminoazobenzene and 20-methylcholanthrene were simultaneously administered.

1952 • 126 citations

EFFECTS OF PHENOTHIAZINES ON PROTECTIVE SYSTEMS AGAINST POLYCYCLIC HYDROCARBONS.

1965 • 116 citations

AROMATIC INFLUENCES ON THE YIELDS OF MAMMARY CANCERS FOLLOWING ADMINISTRATION OF 7,12-DIMETHYLBENZ( a )ANTHRACENE

1964 • 107 citations

Differences in the kinetics of benzpyrene hydroxylation by hepatic drug-metabolizing enzymes from phenobarbital and 3-methylcholanthrene-treated rats

1968 • 105 citations

The Hydroxylation of the Carcinogen 2-Acetylaminofluorene by Rat Liver: Stimulation by Pretreatment in Vivo with 3-Methylcholanthrene

1960 • 98 citations

Species Variations in the N - and Ring-Hydroxylation of 2-Acetylaminofluorene and Effects of 3-Methylcholanthrene Pretreatment.

1967 • 87 citations

Inhibition of the Carcinogenic Action of 7,12-Dimethylbenz(a)anthracene by Beta-Naphthoflavone

1968 • 86 citations

Enhancement and inhibition of the induction by 7,12-dimethylbenz(a)anthracene of mammary tumours in female Sprague-Dawley rats

1968 • 54 citations

AROMATIC AZO DERIVATIVES PREVENTING MAMMARY CANCER AND ADRENAL INJURY FROM 7,12-DIMETHYLBENZ(a)ANTHRACENE

1965 • 51 citations

Stimulatory effect of polycyclic hydrocarbons and aromatic azo derivatives on the metabolism of 7,12-dimethylbenz(alpha)anthracene.

1967 • 43 citations

3-Methylcholanthrene as an inhibitor of hepatic cancer induced by 3'-methyl-4-dimethylaminoazobenzene in the diet of the rat: a determination of the time relationships.

1953 • 33 citations

Stimulatory effect of benzo(alpha)pyrene and phenobarbital pretreatment on the biliary excretion of benzo(alpha)pyrene metabolites in the rat.

1970 • 23 citations

Effects of Polynuclear Aromatic Hydrocarbons on Benzpyrene Hydroxylase Activity in Rats.

1964 • 17 citations

STUDIES ON EAR DUCT TUMORS IN RATS PART II: INHIBITORY EFFECT OF METHYLCHOLANTHRENE AND 1,2-BENZANTHRACENE ON TUMOR FORMATION BY 4-DIMETHYLAMINOSTILBENE

1965 • 10 citations

[Inhibition of 2-acetylaminofluorene tumors in rats with simultaneously fed 20-methylcholanthrene, 9:10-dimethyl-1:2-benzanthracene and chrysene, and consideration of sex difference in tumor genesis with 2-acetyl-aminoflurene].

1953 • 9 citations