Preoperative (neoadjuvant) chemotherapy in patients with breast cancer

Effect of preoperative chemotherapy on the outcome of women with operable breast cancer.

1998 • 2,115 citations

Systemic treatment of early breast cancer by hormonal, cytotoxic, or immune therapy

1992 • 2,084 citations

Effect of preoperative chemotherapy on local-regional disease in women with operable breast cancer: findings from National Surgical Adjuvant Breast and Bowel Project B-18.

1997 • 1,783 citations

Eight-Year Results of a Randomized Clinical Trial Comparing Total Mastectomy and Lumpectomy with or without Irradiation in the Treatment of Breast Cancer

1989 • 1,604 citations

Reanalysis and Results after 12 Years of Follow-up in a Randomized Clinical Trial Comparing Total Mastectomy with Lumpectomy with or without Irradiation in the Treatment of Breast Cancer

1995 • 1,480 citations

A mathematic model for relating the drug sensitivity of tumors to their spontaneous mutation rate.

1979 • 1,331 citations

Clinical Course of Breast Cancer Patients With Complete Pathologic Primary Tumor and Axillary Lymph Node Response to Doxorubicin-Based Neoadjuvant Chemotherapy

1999 • 1,315 citations

Preoperative chemotherapy for osteogenic sarcoma:Selection of postoperative adjuvant chemotherapy based on the response of the primary tumor to preoperative chemotherapy

1982 • 1,079 citations

Systemic Treatment of Early Breast Cancer by Hormonal, Cytotoxic, or Immune Therapy:133 Randomised Trials involoving 31 000 Recurrences and 24 000 Deaths Among 75 000 Women (Summary)

1993 • 967 citations

Effects of Radiotherapy and Surgery in Early Breast Cancer — An Overview of the Randomized Trials

1996 • 789 citations

Primary Chemotherapy To Avoid Mastectomy in Tumors With Diameters of Three Centimeters or More

1990 • 628 citations

Tamoxifen and Chemotherapy for Lymph Node-Negative, Estrogen Receptor-Positive Breast Cancer

1997 • 525 citations

Neoadjuvant versus adjuvant chemotherapy in premenopausal patients with tumours considered too large for breast conserving surgery: Preliminary results of a randomised trial: S6

1994 • 435 citations

Influence of the interval between primary tumor removal and chemotherapy on kinetics and growth of metastases.

1983 • 427 citations

Effects of radiotherapy and surgery in early breast cancer. An overview of the randomized trials. Early Breast Cancer Trialists' Collaborative Group.

1995 • 421 citations

Effect of surgical removal on the growth and kinetics of residual tumor.

1979 • 414 citations

Laboratory and clinical research in breast cancer--a personal adventure: the David A. Karnofsky memorial lecture.

1980 • 367 citations

Randomized trial of chemoendocrine therapy started before or after surgery for treatment of primary breast cancer.

1995 • 348 citations

A reduction in the requirements for mastectomy in a randomized trial of neoadjuvant chemoendocrine therapy in primary breast cancer

1998 • 322 citations

Effects of primary chemotherapy in conservative treatment of breast cancer patients with operable tumors larger than 3 cm

1991 • 277 citations

Results of neoadjuvant chemotherapy and radiation therapy in the breast-conserving treatment of 250 patients with all stages of infiltrative breast cancer

1990 • 267 citations

Prospective Evaluation of Paclitaxel Versus Combination Chemotherapy With Fluorouracil, Doxorubicin, and Cyclophosphamide as Neoadjuvant Therapy in Patients With Operable Breast Cancer

1999 • 253 citations

Kinetics of mammary tumor cell growth and implications for therapy

1971 • 240 citations

Preoperative chemotherapy and radiation therapy for patients with cancer of the esophagus: a potentially curative approach.

1984 • 226 citations

Breast tumour response to primary chemotherapy predicts local and distant control as well as survival

1995 • 158 citations

Residual metastatic axillary lymph nodes following neoadjuvant chemotherapy predict disease-free survival in patients with locally advanced breast cancer

1998 • 156 citations

Clinical and pathological response to primary chemotherapy in operable breast cancer

1997 • 125 citations

Preoperative chemotherapy: a model for studying the biology and therapy of primary breast cancer.

1995 • 108 citations

Primary medical (neo-adjuvant) chemotherapy for operable breast cancer

1993 • 104 citations

Neoadjuvant chemotherapy in 126 operable breast cancers☆

1992 • 92 citations

Preoperative reductive chemotherapy for locally advanced carcinoma of the oral cavity, oropharynx, and hypopharynx

1983 • 80 citations

Chemotherapy Before and After Mastectomy in Stage III Breast Cancer

1982 • 70 citations

NSABP Protocol B-27. Preoperative doxorubicin plus cyclophosphamide followed by preoperative or postoperative docetaxel.

1997 • 66 citations

Preoperative chemotherapy followed by mastectomy for locally advanced breast cancer

1983 • 59 citations

Docetaxel as neoadjuvant chemotherapy in patients with stage III breast cancer.

1997 • 55 citations

Overview of National Surgical Adjuvant Breast Project neoadjuvant chemotherapy studies.

1998 • 50 citations

The management of nonmetastatic locally advanced breast cancer using primary induction chemotherapy with hormonal synchronization followed by radiation therapy with or without debulking surgery

1985 • 46 citations

Phase I trials of dexrazoxane and other potential applications for the agent.

1998 • 37 citations

Preoperative chemotherapy of operable breast cancer (stage IIIA). Prognostic factors of distant recurrence

1993 • 7 citations