Quantitative imaging of neuroreceptors in the living human brain

Opiate Receptor: Demonstration in Nervous Tissue

1973 • 2,364 citations

Dopamine Receptor Binding Predicts Clinical and Pharmacological Potencies of Antischizophrenic Drugs

1976 • 2,224 citations

Neurotransmitter receptor binding

1978 • 822 citations

Imaging Dopamine Receptors in the Human Brain by Positron Tomography

1983 • 743 citations

Effects of Age on Dopamine and Serotonin Receptors Measured by Positron Tomography in the Living Human Brain

1984 • 701 citations

Alzheimer's disease : senile dementia and related disorders

1978 • 369 citations

Influence of age and time interval between death and autopsy on dopamine and 3-methoxytyramine Levels in human basal ganglia

1976 • 328 citations

Regional distribution of methionine-enkephalin and substance P-like immunoreactivity in normal human brain and in Huntington's disease

1980 • 289 citations

Noradrenaline: Fate and Control of Its Biosynthesis

1971 • 287 citations

Imaging Opiate Receptors in the Human Brain by Positron Tomography

1985 • 256 citations

Age‐Correlated Loss of Dopaminergic Binding Sites in Human Basal Ganglia

1982 • 212 citations

Age-related Changes in the Nigrostriatum: A Behavioral and Biochemical Analysis

1978 • 197 citations

Reduced dopaminergic binding during aging in the rodent striatum

1980 • 197 citations

Catecholamines

1972 • 149 citations

Radiosynthesis of an opiate receptor binding radiotracer: [11C]carfentanil

1985 • 149 citations

Dopamine receptor binding in vivo: The feasibility of autoradiographic studies

1978 • 136 citations

Brain Dopamine and Serotonin Receptor Sites Revealed by Digital Subtraction Autoradiography

1985 • 106 citations

Specific in vivo binding of neuroleptic drugs in rat brain

1977 • 99 citations

Catecholamine levels and turnover during aging in brain regions of male C57BL/6J mice

1981 • 90 citations

(3-N-[11C]methyl)spiperone, a ligand binding to dopamine receptors: radiochemical synthesis and biodistribution studies in mice.

1984 • 90 citations

Aging process affects a single class of dopamine receptors

1980 • 88 citations

Dihydropteridine reductase and tyrosine hydroxylase activities in rat brain during development and senescence: a comparative study

1977 • 53 citations

Selective reduction of one class of dopamine receptor binding sites in the corpus striatum of aged rats

1982 • 51 citations

Atlas of Dopamine Receptor Images (PET) of the Human Brain

1985 • 26 citations

Radiolabeled drugs as probes of central nervous system neurons.

1985 • 9 citations