Helicobacter pylori Arginase Inhibits T Cell Proliferation and Reduces the Expression of the TCR ζ-Chain (CD3ζ)

The complete genome sequence of the gastric pathogen Helicobacter pylori

1997 • 3,529 citations

Genomic-sequence comparison of two unrelated isolates of the human gastric pathogen Helicobacter pylori

1999 • 1,904 citations

SHP-2 Tyrosine Phosphatase as an Intracellular Target of Helicobacter pylori CagA Protein

2002 • 1,004 citations

Regulation of T Cell Receptor CD3ζ Chain Expression byl-Arginine

2002 • 460 citations

<scp>l</scp>-Arginine Consumption by Macrophages Modulates the Expression of CD3ζ Chain in T Lymphocytes

2003 • 458 citations

Importance of childhood socioeconomic status on the current prevalence of Helicobacter pylori infection.

1994 • 433 citations

Helicobacter pyloriarginase inhibits nitric oxide production by eukaryotic cells: A strategy for bacterial survival

2001 • 367 citations

Activation of IL-8 gene expression by Helicobacter pylori is regulated by transcription factor nuclear factor-kappa B in gastric epithelial cells.

1998 • 363 citations

Degradation of T Cell Receptor (TCR)–CD3-ζ Complexes after Antigenic Stimulation

1997 • 316 citations

Genetic Evidence for Differential Coupling of Syk Family Kinases to the T-Cell Receptor: Reconstitution Studies in a ZAP-70-Deficient Jurkat T-Cell Line

1998 • 269 citations

Gastric MALT lymphoma: from aetiology to treatment

2002 • 247 citations

Activation of IL-8 Gene Expression byHelicobacter pyloriIs Regulated by Transcription Factor Nuclear Factor-κB in Gastric Epithelial Cells

1998 • 234 citations

Virulent Strains of Helicobacter pylori Demonstrate Delayed Phagocytosis and Stimulate Homotypic Phagosome Fusion in Macrophages

2000 • 207 citations

Helicobacter pylori Genotypes May Determine Gastric Histopathology

2001 • 204 citations

Helicobacter pylori Induces Macrophage Apoptosis by Activation of Arginase II

2002 • 169 citations

Analysis of amino acids in human serum by isocratic reversed-phase high-performance liquid chromatography with electrochemical detection

2001 • 149 citations

Heterogeneity in the Helicobacter pylori vacA and cagA genes: association with gastroduodenal disease in South Africa?

1999 • 146 citations

Human Immunodeficiency Virus-Specific Circulating CD8 T Lymphocytes Have Down-Modulated CD3ζ and CD28, Key Signaling Molecules for T-Cell Activation

2000 • 126 citations

Helicobacter pylori inhibits phagocytosis by professional phagocytes involving type IV secretion components

2000 • 116 citations

Helicobacter pylori rocF Is Required for Arginase Activity and Acid Protection In Vitro but Is Not Essential for Colonization of Mice or for Urease Activity

1999 • 115 citations

L-Arginine regulates the expression of the T-cell receptor zeta chain (CD3zeta) in Jurkat cells.

2001 • 113 citations

Negative Selection of T Cells byHelicobacter pylorias a Model for Bacterial Strain Selection by Immune Evasion

2001 • 112 citations

Two‐thirds of Atrophic Body Gastritis Patients Have Evidence of Helicobacter pylori Infection

2001 • 101 citations

Helicobacter pylori and Socioeconomic Factors in Russia

1996 • 100 citations

Immunobiology of Helicobacter pylori infection

1997 • 90 citations

Changes in Expression of Signal Transduction Proteins in T Lymphocytes of Patients with Leprosy

1998 • 89 citations

Association of Helicobacter pylori infection with dyspeptic symptoms in patients undergoing gastroduodenoscopy

1990 • 85 citations

Cytokine Expression and Production by PurifiedHelicobacter pyloriUrease in Human Gastric Epithelial Cells

2000 • 84 citations

The urea cycle of Helicobacter pylori

1996 • 82 citations

Association of cytotoxin production and neutrophil activation by strains of Helicobacter pylori isolated from patients with peptic ulceration and chronic gastritis.

1996 • 75 citations

Partial characterization of a cell proliferation-inhibiting protein produced by Helicobacter pylori

1996 • 69 citations

Helicobacter pylori Resists Phagocytosis by Macrophages: Quantitative Assessment by Confocal Microscopy and Fluorescence-Activated Cell Sorting

2001 • 66 citations

RecombinantHelicobacter pyloriUrease Activates Primary Mucosal Macrophages

1998 • 63 citations

STIMULATION OF IL-8 PRODUCTION IN HUMAN GASTRIC EPITHELIAL CELLS BYHELICOBACTER PYLORI, IL-1β AND TNF-α REQUIRES TYROSINE KINASE ACTIVITY, BUT NOT PROTEIN KINASE C

1997 • 62 citations

Production of IL-12 in gastritis relates to infection withHelicobacter pylori

1999 • 57 citations

Impaired expression of the CD3‐zeta chain in peripheral blood T cells of patients with chronic myeloid leukaemia results in an increased susceptibility to apoptosis

2000 • 53 citations

Tyrosine Phosphorylation of the Proto-Oncoprotein Raf-1 Is Regulated by Raf-1 Itself and the Phosphatase Cdc25A

1999 • 53 citations

Reduced T‐cell receptor CD3ζ‐chain protein and sustained CD3ε expression at the site of mycobacterial infection

2001 • 51 citations

Peripheral T lymphocytes from women with breast cancer exhibit abnormal protein expression of several signaling molecules

1998 • 49 citations

Lack of gastritis and of an adaptive immune response in interferon regulatory factor-1-deficient mice infected withHelicobacter pylori

2001 • 48 citations

Interaction of arginase with metal ions: studies of the enzyme from human liver and comparison with other arginases

1995 • 46 citations

In situ characterization of Helicobacter pylori arginase

1998 • 43 citations

Suppression of human mononuclear cell response byHelicobacter pylori: Effects on isolated monocytes and lymphocytes

1994 • 40 citations

Peripheral T lymphocytes from women with breast cancer exhibit abnormal protein expression of several signaling molecules

1998 • 39 citations

Decreased Expression of ζ Molecules by T Lymphocytes Is Correlated with Disease Progression in Human Immunodeficiency Virus–Infected Persons

1999 • 38 citations

Immune suppressive effects of Helicobacter pylori on human peripheral blood mononuclear cells

1993 • 37 citations

&lt;i&gt;Helicobacter pylori &lt;/i&gt;Infection as a Model for Gastrointestinal Immunity and Chronic Inflammatory Diseases

2001 • 37 citations

Host Response and Vaccine Development to Helicobacter pylori Infection

1999 • 30 citations

Diagnostic value of endoscopic signs of gastritis: with special emphasis to nodular antritis

1999 • 30 citations

Chronic gastritis and Helicobacter pylori.

2001 • 28 citations

Mechanism for Helicobacter pylori stimulation of interleukin-8 production in a gastric epithelial cell line (MKN 28): roles of mitogen-activated protein kinase and interleukin-1β 1 1Abbreviations: MAPK, mitogen-activated protein kinase; IL, interleukin; TNF, tumor necrosis factor; IFN, interferon; FBS, fetal bovine serum; CFU, colony-forming units; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; RT-PCR, reverse transcriptase-polymerase chain reaction; PDTC, pyrrolidine-carbodithioic acid; NF-…

2001 • 27 citations

T-cell-mediated mucosal immunity in the absence of antibody: lessons fromHelicobacter pyloriinfection

2001 • 20 citations

Impaired expression of the CD3-zeta chain in peripheral blood T cells of patients with chronic myeloid leukaemia results in an increased susceptibility to apoptosis

2000 • 15 citations

[Epidemiologic and clinical aspects of Helicobacter pylori infection in children].

2001 • 13 citations

Symptom score does not correlate with gastritis grade and Helicobacter pylori infection in non ulcer dyspepsia.

2002 • 12 citations

Regression of MALT lymphomas coexisting in the duodenal bulb and the stomach by eradication of Helicobacter pylori

2002 • 11 citations

The role of Helicobacter pylori infection in the pathogenesis of gastritis.

1994 • 8 citations

Th1/Th2 lymphocyte responses in Helicobacter infections

1998 • 8 citations

Role of gastric mucosal cytokines in the immunopathogenesis of Helicobacter pylori infection: new hypotheses but still few certitudes

1997 • 5 citations