Retinoid-Induced Hypertriglyceridemia in Rats Is Mediated by Retinoic Acid Receptors

Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers.

1993 • 940 citations

The retinoid receptors.

1994 • 665 citations

Design and Synthesis of Potent Retinoid X Receptor Selective Ligands That Induce Apoptosis in Leukemia Cells

1995 • 332 citations

Changes in Plasma Lipids and Lipoproteins during Isotretinoin Therapy for Acne

1985 • 216 citations

Separation of Transactivation and AP1 Antagonism Functions of Retinoic Acid Receptor α

1995 • 168 citations

Determination of peroxisomal fatty acyl-CoA oxidase activity using a lauroyl-CoA-based fluorometric assay

1986 • 100 citations

ChemInform Abstract: AROTINOIDS, A NEW CLASS OF HIGHLY ACTIVE RETINOIDS

1980 • 94 citations

9-cis retinoic acid induces complete remission but does not reverse clinically acquired retinoid resistance in acute promyelocytic leukemia

1995 • 92 citations

All-trans retinoic acid: tolerance and biologic effects in myelodysplastic syndrome.

1993 • 63 citations

Section Review: Retinoids: Biological Function and Use in the Treatment of Dermatological Diseases: Pulmonary-Allergy, Dermatological, Gastrointestinal & Arthritis

1995 • 51 citations

Marked hyperlipidemia and pancreatitis associated with isotretinoin therapy.

1992 • 51 citations

Hyperlipidaemia due to isotretinoin and etretinate: possible mechanisms and consequences

1986 • 50 citations

Etretinate Therapy Causes Increases in Lipid Levels in Patients With Psoriasis

1982 • 50 citations

Synthesis and Structure-Activity Relationships of Stilbene Retinoid Analogs Substituted with Heteroaromatic Carboxylic Acids

1995 • 47 citations

Retinoid-Induced Epiphyseal Plate Closure in Guinea Pigs

1996 • 46 citations

Changes in lipid metabolism during retinoid administration

1982 • 43 citations

Serum lipid changes during acitretin (etretin) treatment of psoriasis and palmo-plantar pustulosis.

1988 • 40 citations

Specific Antagonist of Retinoid Toxicity in Mice

1996 • 40 citations

Retinoid X receptor-specific retinoids inhibit the ability of retinoic acid receptor-specific retinoids to increase the level of insulin-like growth factor binding protein-3 in human ectocervical epithelial cells.

1996 • 38 citations

Effect of Retinoic Acid and Retinyl Acetate Feeding Upon Lipid Metabolism in Adrenalectomized Rats

1979 • 37 citations

A retinoic acid receptor α antagonist counteracts retinoid teratogenicity in vitro and reduced incidence and/or severity of malformations in vivo

1994 • 32 citations

The effects of a novel potent oral retinoid (Ro13-6298) in the treatment of multiple solar keratoses and squamous cell epithelioma

1983 • 32 citations

Metabolism of very low density lipoproteins in rats with isotretinoin (13-cis retinoic acid)-induced hyperlipidemia.

1990 • 31 citations

New Indications and New Retinoids

1987 • 28 citations

The influence of Tigason' (Ro 10–9359) on the serum lipoproteins in man

1981 • 28 citations

New Retinoids for Dermatologic Diseases: Uses and Toxicity

1988 • 27 citations

Plasma fat elimination tissue lipoprotein lipase activity and plasma fatty acid composition during sequential treatment with etretinate and isotretinoin

1987 • 23 citations

Synthesis and pharmacological activity of conformationally restricted, acetylenic retinoid analogs

1995 • 15 citations

Retinoids in the treatment of acute promyelocytic leukemia

1995 • 11 citations

Arotinoid ethyl ester (Ro 13-6298): a long term pilot study in various dermatoses

1987 • 11 citations

ALL-Trans Retinoic Acid (ATRA) in the Treatment of Myelodysplastic Syndromes: Results in 5 Cases

1994 • 5 citations

DEVELOPMENT OF RAR SUBTYPE SELECTIVE RETINOIDS FOR DERMATOLOGICAL DISEASES

1995 • 4 citations

Effect of heparin on vitamin A induced hyperlipidemia in rats.

1981 • 3 citations

ChemInform Abstract: Synthesis and Characterization of a Highly Potent and Effective Antagonist of Retinoic Acid Receptors.

1996 • 1 citations