Plasma Membrane Transport of Thyroid Hormones and Its Role in Thyroid Hormone Metabolism and Bioavailability

The Thyroid Gland.

1965 • 1,816 citations

Expression Cloning and Characterization of a Transporter for Large Neutral Amino Acids Activated by the Heavy Chain of 4F2 Antigen (CD98)

1998 • 1,051 citations

Cloning and Expression of a Plasma Membrane Cystine/Glutamate Exchange Transporter Composed of Two Distinct Proteins

1999 • 982 citations

Protein disulphide isomerase: building bridges in protein folding

1994 • 718 citations

Molecular Identification and Characterization of Novel Members of the Human Organic Anion Transporter (OATP) Family

2000 • 636 citations

A Novel Human Hepatic Organic Anion Transporting Polypeptide (OATP2)

1999 • 630 citations

A novel human organic anion transporting polypeptide localized to the basolateral hepatocyte membrane

2000 • 611 citations

Relationships between Circulating and Intracellular Thyroid Hormones: Physiological and Clinical Implications*

1981 • 549 citations

Identification of a Novel Gene Family Encoding Human Liver-specific Organic Anion Transporter LST-1

1999 • 546 citations

Amino-acid transport by heterodimers of 4F2hc/CD98 and members of a permease family

1998 • 545 citations

Expression cloning of a rat liver Na(+)-independent organic anion transporter.

1994 • 535 citations

Localization and Genomic Organization of a New Hepatocellular Organic Anion Transporting Polypeptide

2000 • 516 citations

Identification and Functional Characterization of a Na+-independent Neutral Amino Acid Transporter with Broad Substrate Selectivity

1999 • 479 citations

Functional expression cloning and characterization of the hepatocyte Na+/bile acid cotransport system.

1991 • 479 citations

Selective expression of the large neutral amino acid transporter at the blood–brain barrier

1999 • 457 citations

Molecular cloning, chromosomal localization, and functional characterization of a human liver Na+/bile acid cotransporter.

1994 • 444 citations

Transport of Protein-Bound Hormones into Tissuesin Vivo*

1981 • 435 citations

Molecular and functional characterization of an organic anion transporting polypeptide cloned from human liver

1995 • 419 citations

Identification and Characterization of a Prostaglandin Transporter

1995 • 400 citations

Isolation of a multispecific organic anion and cardiac glycoside transporter from rat brain

1997 • 396 citations

Identification of a Membrane Protein, LAT-2, That Co-expresses with 4F2 Heavy Chain, an L-type Amino Acid Transport Activity with Broad Specificity for Small and Large Zwitterionic Amino Acids

1999 • 395 citations

Proteins Associated with the Thyroid Hormones

1960 • 358 citations

LAT2, a New Basolateral 4F2hc/CD98-associated Amino Acid Transporter of Kidney and Intestine

1999 • 354 citations

Molecular Characterization and Tissue Distribution of a New Organic Anion Transporter Subtype (oatp3) That Transports Thyroid Hormones and Taurocholate and Comparison with oatp2

1998 • 338 citations

Identification and Characterization of a Membrane Protein (y+L Amino Acid Transporter-1) That Associates with 4F2hc to Encode the Amino Acid Transport Activity y+L

1998 • 329 citations

Cloning and Functional Expression of a Human Na+and Cl−-dependent Neutral and Cationic Amino Acid Transporter B0+

1999 • 325 citations

4F2 (CD98) Heavy Chain Is Associated Covalently with an Amino Acid Transporter and Controls Intracellular Trafficking and Membrane Topology of 4F2 Heterodimer

1999 • 317 citations

Non-type I cystinuria caused by mutations in SLC7A9, encoding a subunit (bo,+AT) of rBAT

1999 • 315 citations

Transthyretin

1986 • 311 citations

Effect of amiodarone on serum triiodothyronine, reverse triiodothyronine, thyroxin, and thyrotropin. A drug influencing peripheral metabolism of thyroid hormones.

1976 • 309 citations

Cloning and molecular characterization of the ontogeny of a rat ileal sodium-dependent bile acid transporter.

1995 • 305 citations

Expression and transport properties of the human ileal and renal sodium-dependent bile acid transporter

1998 • 294 citations

Identification of SLC7A7, encoding y+LAT-1, as the lysinuric protein intolerance gene

1999 • 293 citations

Identification and Characterization of a Na+-independent Neutral Amino Acid Transporter That Associates with the 4F2 Heavy Chain and Exhibits Substrate Selectivity for Small Neutral d- and l-Amino Acids

2000 • 275 citations

Identification of Glutathione as a Driving Force and Leukotriene C4 as a Substrate for oatp1, the Hepatic Sinusoidal Organic Solute Transporter

1998 • 274 citations

Thyroid Hormone Metabolism and Thyroid Diseases in Chronic Renal Failure

1996 • 269 citations

Thyroid Hormone Metabolism

1994 • 268 citations

Amino acid transport of y+L-type by heterodimers of 4F2hc/CD98 and members of the glycoprotein-associated amino acid transporter family

1999 • 262 citations

SLC7A7, encoding a putative permease-related protein, is mutated in patients with lysinuric protein intolerance

1999 • 248 citations

Human LAT1, a Subunit of System L Amino Acid Transporter: Molecular Cloning and Transport Function

1999 • 246 citations

Cloning, in vitro expression, and tissue distribution of a human prostaglandin transporter cDNA(hPGT).

1996 • 235 citations

Identification of a Mutation in the Ileal Sodium-dependent Bile Acid Transporter Gene That Abolishes Transport Activity

1995 • 221 citations

The interaction of thyroid hormones and protein in biological fluids.

1957 • 199 citations

Cloning and Functional Characterization of a Novel Rat Organic Anion Transporter Mediating Basolateral Uptake of Methotrexate in the Kidney

1996 • 199 citations

The heterodimeric amino acid transporter 4F2hc/y+LAT2 mediates arginine efflux in exchange with glutamine

2000 • 195 citations

Thyroxine transport from blood to brain via transthyretin synthesis in choroid plexus

1990 • 189 citations

Identification of an Amino Acid Transporter Associated with the Cystinuria-related Type II Membrane Glycoprotein

1999 • 189 citations

Peripheral Serum Thyroxine, Triiodothyronine and Reverse Triiodothyronine Kinetics in the Low Thyroxine State of Acute Nonthyroidal Illnesses

1982 • 187 citations

Surface Antigen CD98(4F2): Not a Single Membrane Protein, But a Family of Proteins with Multiple Functions

2000 • 185 citations

Identification of Thyroid Hormone Transporters in Humans: Different Molecules Are Involved in a Tissue-Specific Manner*,†

2001 • 183 citations

New Glycoprotein-Associated Amino Acid Transporters

1999 • 178 citations

Thyroxine transport in choroid plexus.

1987 • 177 citations

Identification of Thyroid Hormone Transporters

1999 • 177 citations

Rat choroid plexus specializes in the synthesis and the secretion of transthyretin (prealbumin). Regulation of transthyretin synthesis in choroid plexus is independent from that in liver.

1986 • 167 citations

Thyroid Hormone Transport by the Heterodimeric Human System L Amino Acid Transporter

2001 • 167 citations

High affinity thyroid hormone binding sites on purified rat liver plasma membranes

1977 • 166 citations

Identification of organic anion transporting polypeptide 4 (Oatp4) as a major full-length isoform of the liver-specific transporter-1 (rlst-1) in rat liver

2000 • 144 citations

Regulation of the peripheral metabolism of the thyroid hormones.

1960 • 137 citations

Concentrations of Thyroxine and 3,5,3′-Triiodothyronine at 34 Different Sites in Euthyroid Rats as Determined by an Isotopic Equilibrium Technique

1985 • 130 citations

Luminal Heterodimeric Amino Acid Transporter Defective in Cystinuria

1999 • 128 citations

Cloning and functional characterization of a new multispecific organic anion transporter, OAT-K2, in rat kidney.

1999 • 125 citations

Characteristics of active transport of thyroid hormone into rat hepatocytes

1981 • 117 citations

Cloning and characterization of a human brain Na+-independent transporter for small neutral amino acids that transports d-serine with high affinity

2000 • 112 citations

Transport of iodothyronines from bloodstream to brain: contributions by blood:brain and choroid plexus:cerebrospinal fluid barriers

1991 • 112 citations

The effects of drugs on the distribution and metabolism of thyroid hormones.

1981 • 111 citations

Active transport of triiodothyronine (T₃) into isolated rat liver cells

1978 • 110 citations

Genetic heterogeneity in cystinuria: the SLC3A1 gene is linked to type I but not to type III cystinuria.

1995 • 109 citations

Regulation of the Conversion of Thyroxine to Triiodothyronine in the Perfused Rat Liver

1979 • 106 citations

A furan fatty acid and indoxyl sulfate are the putative inhibitors of thyroxine hepatocyte transport in uremia.

1993 • 105 citations

Inhibition of thyroxine transport into cultured rat hepatocytes by serum of nonuremic critically ill patients: effects of bilirubin and nonesterified fatty acids.

1993 • 104 citations

Triiodothyronine Is a High‐Affinity Inhibitor of Amino Acid Transport System L₁ in Cultured Astrocytes

1993 • 102 citations

Molecular characterization and functional regulation of a novel rat liver-specific organic anion transporter rlst-1

1999 • 102 citations

Decreased transport of thyroxine (T₄), 3,3′‐5‐triiodothyronine (T₃) and 3,3′,5′‐triiodothyronine (rT₃) into rat hepatocytes in primary culture due to a decrease of cellular ATP content and various drugs

1982 • 97 citations

How specific are nuclear “receptors” for thyroid hormones?

1975 • 96 citations

Cloning and functional characterization of a Na+-independent, broad-specific neutral amino acid transporter from mammalian intestine

2000 • 95 citations

Thyroid hormone metabolism in a transthyretin-null mouse strain

1994 • 93 citations

Characterization of the thyroid hormone transport system of isolated hepatocytes.

1988 • 90 citations

Decreased serum triiodothyronine in starving rats is due primarily to diminished thyroidal secretion of thyroxine.

1985 • 86 citations

Serum Reverse Triiodothyronine and Thyroxine Kinetics in Patients with Chronic Renal Failure*

1983 • 86 citations

Uptake of thyroid hormones in neonatal rat cardiac myocytes.

1996 • 85 citations

Uptake of thyroid hormone by isolated rat liver cells

1976 • 84 citations

Hormone delivery systems to the brain - transthyretin

2009 • 78 citations

Uptake of L-tri-iodothyronine by isolated rat liver cells. A process partially inhibited by metabolic inhibitors; attempts to distinguish between uptake and binding to intracellular proteins

1979 • 78 citations

Regulation of organic anion and drug transporters of the sinusoidal membrane

1999 • 76 citations

Brain and Cerebrospinal Fluid Permeability to Intravenous Thyroid Hormones*

1974 • 76 citations

Inhibition of Hepatic Binding of Thyroxine by Cholecystographic Agents

1980 • 74 citations

Multiple Effects of 5,5′-Diphenylhydantoin on the Thyroid Hormone System*

1984 • 72 citations

Transthyretin is not essential for thyroxine to reach the brain and other tissues in transthyretin-null mice

1997 • 72 citations

Molecular cloning and functional characterization of the mouse organic-anion-transporting polypeptide 1 (Oatp1) and mapping of the gene to chromosome X

1999 • 71 citations

Effects of caloric deprivation on thyroid hormone tissue uptake and generation of low-T3 syndrome

1986 • 71 citations

The Transport of Thyroxine into Mouse Neuroblastoma Cells, NB41A3: The Effect of L-System Amino Acids*

1990 • 69 citations

Thyroid hormone transport by 4F2hc-IU12 heterodimers expressed in Xenopus oocytes

1999 • 66 citations

High affinity L-triiodothyronine binding sites on washed rat erythrocyte membranes.

1983 • 66 citations

High affinity thyroxine binding to purified rat liver plasma membranes

1979 • 64 citations

Characterization of Binding and Uptake of 3,3′,5-Triido-L-Thyronine in Cultured Mouse Fibroblasts

1983 • 64 citations

Elevated 3,5-Diiodothyronine Concentrations in the Sera of Patients with Nonthyroidal Illnesses and Brain Tumors

1997 • 64 citations

The Influence of Extracellular Thyroxine-Binding Protein upon the Accumulation of Thyroxine by Tissue Slices 12

1957 • 64 citations

CARRIER-MEDIATED TRANSPORT OF THYROID HORMONE INTO RAT HEPATOCYTES IS RATE-LIMITING IN TOTAL CELLULAR UPTAKE AND METABOLISM

1986 • 64 citations

Evidence for a close link between the thyroid hormone transport system and the aromatic amino acid transport system T in erythrocytes.

1990 • 63 citations

The binding of thyroid hormones to phospholipid membranes

1970 • 63 citations

Thyroid hormone concentrative uptake in rat erythrocytes. Involvement of the tryptophan transport system T in countertransport of tri-iodothyronine and aromatic amino acids

1992 • 62 citations

Rapid stimulation in vitro of rat liver cytochrome oxidase activity by 3,5-diiodo-l-thyronine and by 3,3′-diiodo-l-thyronine

1994 • 58 citations

Affinity labeling of the plasma membrane 3,3',5-triiodo-L-thyronine receptor in GH3 cells.

1982 • 58 citations

Thyroxine Transfer and Distribution in Critical Nonthyroidal Illnesses, Chronic Renal Failure, and Chronic Ethanol Abuse*

1987 • 57 citations

Fetal and Neonatal Expression of the Apical Sodium-Dependent Bile Acid Transporter in the Rat Ileum and Kidney1

1997 • 57 citations

Concentration of taurine, beta-alanine, and triiodothyronine by ascites carcinoma cells.

1954 • 56 citations

Cloning of mouse prostaglandin transporter PGT cDNA: species-specific substrate affinities

1999 • 56 citations

Differential Influence of the 4F2 Heavy Chain and the Protein Related to b0,+ Amino Acid Transport on Substrate Affinity of the Heteromeric b0,+ Amino Acid Transporter

2000 • 55 citations

Transthyretin expression in the rat brain: effect of thyroid functional state and role in thyroxine transport

1993 • 52 citations

Amiodarone and the Thyroid

1997 • 51 citations

Characterization of Triiodothyronine Transport and Accumulation in Rat Erythrocytes*

1988 • 49 citations

Membrane transport of L-triiodthyronine by human red cell ghosts

1979 • 49 citations

Thyroid hormone binding to plasma membrane preparations: studies in different thyroid states and tissues

1981 • 49 citations

Thyroid Hormone Export Regulates Cellular Hormone Content and Response

1996 • 48 citations

Uptake and binding of thyroxine and triiodothyronine by rat diaphragm in vitro

1961 • 47 citations

Pharmacotherapeutics of the Thyroid Gland

1997 • 46 citations

EVIDENCE FOR AN ACTIVE STEP IN THYROID HORMONE TRANSPORT TO NUCLEI: DRUG INHIBITION OF L-¹²⁵I-TRIIODOTHYRONINE BINDING TO NUCLEAR RECEPTORS IN RAT PITUITARY TUMOR CELLS

1982 • 45 citations

Carrier-Mediated Transport of Thyroid Hormones into Rat Glial Cells in Primary Culture

1989 • 45 citations

Different Regulation of Thyroid Hormone Transport in Liver and Pituitary: Its Possible Role in the Maintenance of Low T3 Production during Nonthyroidal Illness and Fasting in Man

1996 • 44 citations

Full-Length cDNA Cloning and Genomic Organization of the Mouse Liver-Specific Organic Anion Transporter-1 (lst-1)

2000 • 44 citations

Thyroid hormone metabolism in nonthyroidal illness

1996 • 44 citations

Rat liver type I iodothyronine deiodinase is not identical to protein disulfide isomerase

1989 • 44 citations

Uptake of triiodothyroacetic acid and its effect on thyrotropin secretion in cultured anterior pituitary cells.

1994 • 43 citations

Uptake of L-triiodothyronine into human cultured lymphocytes

1980 • 42 citations

Active Transport of Iodothyronines into Human Cultured Fibroblasts*

1987 • 42 citations

Molecular Properties of Hepatic Uptake Systems for Bile Acids and Organic Anions

1997 • 41 citations

Characterization of a membrane-associated 3,3',5-triiodo-L-thyronine binding protein by use of monoclonal antibodies

1986 • 41 citations

Transport of 3,5,3'-triiodothyronine into the perfused rat liver and subsequent metabolism are inhibited by fasting.

1992 • 40 citations

Thyroid hormone uptake by hepatocytes: structure-activity relationships of phenylanthranilic acids with inhibitory activity

1993 • 39 citations

Inhibition of iodothyronine transport into rat liver cells by a monoclonal antibody.

1986 • 39 citations

Energy-Dependent Uptake of 3,5,3′-Triiodo-LThyronine in Rat Skeletal Muscle

1986 • 39 citations

Role of sodium in thyroid hormone uptake by rat skeletal muscle.

1987 • 37 citations

The essential role of albumin in the active transport of thyroid hormones into primary cultured rat hepatocytes

1979 • 36 citations

Uptake of 3,5,3′-Triiodothyronine by Cultured Rat Hepatoma Cells Is Inhibitable by Nonbile Acid Cholephils, Diphenylhydantoin, and Nonsteroidal Antiinflammatory Drugs*

1989 • 36 citations

Impaired thyroxine and 3,5,3'-triiodothyronine handling by rat hepatocytes in the presence of serum of patients with nonthyroidal illness.

1995 • 35 citations

Evidence that the uptake of tri-iodo-<scp>l</scp>-thyronine by human erythrocytes is carrier-mediated but not energy-dependent

1982 • 34 citations

Expression of Rat Liver Cell Membrane Transporters for Thyroid Hormone inXenopus laevisOocytes¹

1997 • 34 citations

Transport of thyroxine into cultured hepatocytes: effects of mild non-thyroidal illness and calorie restriction in obese subjects

1994 • 32 citations

Uptake of thyroxine in cultured anterior pituitary cells of euthyroid rats.

1994 • 32 citations

Characterization of the Thyroid Hormone Transport System of Cerebrocortical Rat Neurons in Primary Culture

1995 • 32 citations

Characterization of thyroid hormone transport in synaptosomes from rat brain

1989 • 30 citations

Transport and metabolism of iodothyronines in cultured human hepatocytes.

1993 • 30 citations

Intracellular Transport of 3,5,3′-Triiodo-L-Thyronine in Rat Skeletal Myoblasts*

1987 • 30 citations

Thyroid Hormone Synthesis, Plasma Membrane Transport and Metabolism

1997 • 29 citations

Uptake of 3,3',5,5'-tetraiodothyroacetic acid and 3,3',5'-triiodothyronine in cultured rat anterior pituitary cells and their effects on thyrotropin secretion.

1995 • 29 citations

High affinity L-triiodothyronine binding to right-side-out and inside-out vesicles from rat and human erythrocyte membrane

1989 • 29 citations

Saturable, stereospecific transport of 3,5,3'-triiodo-L-thyronine and L-thyroxine into GH4C1 pituitary cells.

1993 • 28 citations

HYPERTHYROXINAEMIA DUE TO DECREASED PERIPHERAL TRIIODOTHYRONINE PRODUCTION

1982 • 27 citations

Transport of Thyroid Hormones by Human Erythrocytes: Kinetic Characterization in Adults and Newborns*

1990 • 27 citations

Regulation of the active transport of 3,3′,5‐triiodothyronine (T₃) into primary cultured rat hepatocytes by ATP

1980 • 27 citations

Transport of thyroxine across the blood-brain barrier is directed primarily from brain to blood in the mouse

1985 • 27 citations

Relationship between thyroid hormone transport and neutral amino acid transport in JAR human choriocarcinoma cells.

1994 • 27 citations

Characterization of the 3,3′,5-Triiodo-L-Thyronine Binding Site on Plasma Membranes from Human Placenta

1985 • 27 citations

Triiodothyronine binding sites in the rat erythrocyte membrane: involvement in triidothyronine transport and relation to the tryptophan transport System T

1992 • 26 citations

Membrane transport of thyroid hormone in the human choriocarcinoma cell line, JAR

1992 • 26 citations

Phloretin Inhibits Cellular Uptake and Nuclear Receptor Binding of Triiodothyronine in Human Hep G2 Hepatocarcinoma Cells*

1989 • 26 citations

Purification and characterization of 55‐kDa protein with 3,5,3′‐triiodo‐<scp>l</scp>‐thyronine‐binding activity and protein disulfide‐isomerase activity from beef liver membrane

1989 • 26 citations

Evidence for carrier-mediated uptake of triiodothyronine in cultured anterior pituitary cells of euthyroid rats.

1993 • 24 citations

Thyroid Hormone Efflux from Monolayer Cultures of Human Fibroblasts and Hepatocytes. Effect of Lipoproteins and Other Thyroxine Transport Proteins

1998 • 23 citations

Kinetics of internalization and subcellular binding sites for T₃ in mouse liver

1996 • 23 citations

Interaction Between Thyroid Hormones and Erythrocyte Membranes: Competitive Inhibition of Binding¹³¹I-L-Triiodothyronine and¹³¹I-L-Thyroxine by Their Analogs

1976 • 22 citations

Neutral amino acid transport pathways in uptake of L-thyroxine by Ehrlich ascites cells

1975 • 22 citations

Transverse motion of spin-labeled 3,3′,5-triiodo-L-thyronine in phospholipid bilayers

1985 • 22 citations

Different effects of amiodarone on transport of T4 and T3 into the perfused rat liver

1994 • 22 citations

Film autoradiography identifies unique features of [125I]3,3'5'-(reverse) triiodothyronine transport from blood to brain

1994 • 22 citations

Decreased peripheral 3,5,3'-triiodothyronine (T3) production from thyroxine (T4): a syndrome of impaired thyroid hormone activation due to transport inhibition of T4- into T3-producing tissues.

1993 • 21 citations

Characteristics of the Uptake of 3,5,3′-Triiodo-l-thyronine andl-Thyroxine into Red Blood Cells of Rainbow Trout (Oncorhynchus mykiss)

1996 • 21 citations

Trans-stimulation effects of folic acid derivatives on methotrexate transport by rat renal organic anion transporter, OAT-K1.

2000 • 21 citations

Handling of iodothyronines by the liver and kidney in patients with chronic liver disease

1987 • 20 citations

High-affinity binding of thyroid hormones to neuroblastoma plasma membranes

1990 • 20 citations

Differential effect of a new thyromimetic on triiodothyronine transport into myoblasts and hepatoma and neuroblastoma cells

1992 • 19 citations

Solubilization of L-triiodothyronine binding site from human erythrocyte membrane

1985 • 19 citations

SLC7A8, a Gene Mapping within the Lysinuric Protein Intolerance Critical Region, Encodes a New Member of the Glycoprotein-Associated Amino Acid Transporter Family

1999 • 19 citations

The release of thyroxine from serum protein in the vessels of the liver

1969 • 19 citations

Positive Regulation of the Guinea Pig Thyrotropin Receptor*

1985 • 19 citations

Thyroid Hormone Export in Rat FRTL-5 Thyroid Cells and Mouse NIH-3T3 Cells Is Carrier-Mediated, Verapamil-Sensitive, and Stereospecific1

1999 • 19 citations

Characterization of l-Thyroxine Transport into Hepatocytes Isolated from Juvenile Rainbow Trout (Oncorhynchus mykiss)

1993 • 19 citations

Uptake of l-tri-iodothyronine by human cultured trophoblast cells

1992 • 19 citations

3,5,3′-Triiodo-l-thyronine andl-Thyroxine Uptake into Red Blood Cells of Rainbow Trout,Oncorhynchus mykiss

1996 • 19 citations

Possible etiology for euthyroid sick syndrome

1993 • 19 citations

The Endocrine Response to Acute Illness

1999 • 19 citations

Thyroid hormone transport in a human glioma cell line

1990 • 18 citations

Effects of a furan fatty acid and indoxyl sulfate on thyroid hormone uptake in cultured anterior pituitary cells

1995 • 18 citations

Characterization of 3,5,3′-Triiodo-L-thyronine Transport into Hepatocytes Isolated from Juvenile Rainbow Trout (Oncorhynchus mykiss), and Comparison with L-Thyroxine Transport

1994 • 18 citations

Influence of calmodulin antagonists and calcium channel blockers on triiodothyronine uptake by rat hepatoma and myoblast cell lines

1993 • 18 citations

Benzodiazepines inhibit temperature-dependent L-[125I]triiodothyronine accumulation into human liver, human neuroblast, and rat pituitary cell lines.

1992 • 17 citations

THE CONCENTRATION AND BINDING OF THYROXINE AND TRIIODOTHYRONINE BY RAT DIAPHRAGM 1

1957 • 17 citations

Identification by photoaffinity labeling of a membrane thyroid hormone-binding protein associated with the triiodothyronine transport system in rat erythrocytes.

1993 • 17 citations

Relationship between the thyroid hormone transport system and the Na(+)-H+ exchanger in cultured rat brain astrocytes.

1995 • 17 citations

Regulation of influx and efflux of thyroid hormones in rat hepatocytes: possible physiologic significance of the plasma membrane in the regulation of thyroid hormone activity.

1984 • 17 citations

Inhibition of Thyroid Hormone Uptake by Calcium Antagonists of the Dihydropyridine Class

1997 • 16 citations

l-Thyroxine enters the rat liver cell by simple diffusion

1983 • 16 citations

The triiodothyronine carrier of rat erythrocytes

1990 • 16 citations

Effects of fasting, intermittent feeding, or continuous parenteral nutrition on rat liver and brain energy metabolism as assessed by 31P-NMR

1995 • 16 citations

Competitive inhibition of thyroid hormone uptake into cultured rat brain astrocytes by bilirubin and bilirubin conjugates

1993 • 16 citations

Kinetics of red blood cell T3 uptake in hypothyroidism with or without hormonal replacement, in the rat

1999 • 16 citations

Comparison of mechanisms mediating uptake and efflux of thyroid hormones in the human choriocarcinoma cell line, JAR

1999 • 15 citations

T4 uptake into the perfused rat liver and liver T4 uptake in humans are inhibited by fructose

1994 • 15 citations

Erythrocyte-associated triiodothyronine in the rat: a source of hormone for target cells

1990 • 15 citations

The uptake and release of thyroxine and tri‐iodothyronine by the perfused rat heart

1968 • 15 citations

Development and Use of a Mathematical Two-Pool Model of Distribution and Metabolism of 3,3′,5-Triiodothyronine in a Recirculating Rat Liver Perfusion System: Albumin Does not Play a Role in Cellular Transport*

1990 • 15 citations

Interactions between thyroid hormone and tryptophan transport in rat liver are modulated by thyroid status

1997 • 15 citations

Uptake and metabolism of thyroid hormones by cultured monkey hepatocarconoma cells Effects of potassium cyanide and dinitrophenol

1978 • 14 citations

Characterization of multidrug-resistant pituitary tumor cells.

1992 • 14 citations

Evidence for thyroxine transport by the lung and heart capillary endothelium

1989 • 14 citations

Inhibition of iodothyronine deiodinase by phenolphthalein dyes

1982 • 14 citations

Thyroxine transport by the choroid plexusin vitro

1975 • 13 citations

Transport and metabolism of iodothyronines in cultured human hepatocytes

1993 • 13 citations

Thyroid hormone uptake in cultured rat anterior pituitary cells: effects of energy status and bilirubin

2000 • 13 citations

Saturable uptake of [125I]l-triiodothyronine at the basolateral (blood) and apical (cerebrospinal fluid) sides of the isolated perfused sheep choroid plexus

1992 • 13 citations

Regulation of conversion of thyroxine to triiodothyronine in perfused rat kidney

1983 • 12 citations

Carrier-Mediated [¹²⁵I]-T₃Uptake by Mouse Thymocytes*

1989 • 12 citations

Rapid Sulfation of 3,3′,5′-Triiodothyronine in NativeXenopus laevisOocytes

1998 • 12 citations

Structural Similarities between the Plasma Membrane Binding Sites for L-Thyroxine and 3,3′,5-Triiodo-L- Thyronine in Cultured Cells

1985 • 11 citations

Drug effects on triiodothyronine uptake by rat anterior pituitary cells in vitro

2009 • 10 citations

Effect of Extracellular Sodium on Thyroid Hormone Uptake by Mouse Thymocytes*

1991 • 10 citations

High level expression of p55, a thyroid hormone binding protein which is homologous to protein disulfide isomerase in a retroviral vector

1989 • 10 citations

Uptake of thyroxine in the human choriocarcinoma cell line JAR

1995 • 10 citations

Modification of l-triiodothyronine binding sites from rat erythrocyte membrane by heating and by proteinase treatments

1987 • 9 citations

Specific 3,3′,5′-Triiodothyronine (Reverse T3) Binding Sites on Rat Liver Plasma Membranes: Comparison with Thyroxine (T4) Binding Sites

1983 • 9 citations

Uptake of triiodothyronine sulfate and suppression of thyrotropin secretion in cultured anterior pituitary cells

1994 • 9 citations

Cerebral expression of transthyretin: evolution, ontogeny and function.

1992 • 9 citations

Adaptive changes in transmembrane transport and metabolism of triiodothyronine in perfused livers of fed and fasted hypothyroid and hyperthyroid rats

1994 • 9 citations

The “Pardridge” hypotheses relating to the role of hormone binding proteins in hormone delivery: A critioue

1988 • 9 citations

Insulin effect on thyroid hormone uptake in rat skeletal muscle

1988 • 9 citations

Factors Influencing the Steady-State Distribution and Exchange of Thyroid Hormones between Red Blood Cells and Plasma of Rainbow Trout,Oncorhynchus mykiss

1998 • 8 citations

Cholecystographic Agents and Sulfobromophthalein Inhibit the Binding of L-Thyroxine to Plasma Membranes of Rat Hepatocytes^*

1986 • 8 citations

Kinetics of Triiodothyronine Uptake by Erythrocytes in Hyperthyroidism, Hypothyroidism, and Thyroid Hormone Resistance*

1989 • 8 citations

Triiodothyronine Production by the Perfused Rat Kidney Is Reduced by Diabetes Mellitus but Not by Fasting*

1985 • 8 citations

Uptake of thyroid hormones (L-T3 and L-T4) by isolated rat adipocytes

1987 • 8 citations

Modeling thyroxine transport to liver: rejection of the "enhanced dissociation" hypothesis as applied to thyroxine

1989 • 8 citations

The Application of anin VitroPerfused Liver Preparation to Examine the Effects of Epinephrine and Bovine Thyroid-Stimulating Hormone on Triiodo-l-thyronine Release from the Liver of Rainbow Trout (Oncorhynchus mykiss)

1998 • 8 citations

Benzodiazepines inhibit temperature-dependent L-[125I]triiodothyronine accumulation into human liver, human neuroblast, and rat pituitary cell lines

1992 • 8 citations

In vivo biliary excretion and in vitro cellular accumulation of thyroxine by rats or cultured rat hepatocytes treated with a novel histamine H1-receptor antagonist

1990 • 8 citations

Changes in renal tri-iodothyronine and thyroxine handling during fasting

2000 • 8 citations

Computer-assisted molecular modeling of benzodiazepine and thyromimetic inhibitors of the HepG2 iodothyronine membrane transporter.

1994 • 7 citations

Uptake of Reverse T3in the Human Choriocarcinoma Cell Line, JAr

1999 • 7 citations

Binding of (125I) triiodothyronine to human peripheral leukocytes and its internalization

1987 • 7 citations

Efflux of T4 from the in situ perfused liver of rainbow trout: effect of T4, dithiothreitol and cysteine in the perfusate

1999 • 7 citations

Requisite structural characteristics for benzodiazepine inhibition of triiodothyronine uptake into a human liver cell line

1992 • 7 citations

Active transport of L-tri-iodothyronine through the red cell plasma membrane—true or false?

1987 • 6 citations

Thyroid Hormone Receptors in Human Cultured Fibroblasts: Evidence for Cellular T₄Transport and Nuclear T₃Binding

1983 • 6 citations

Increase in red blood cell trhodothyronine uptake in untreated unipolar major depressed patients compared to healthy volunteers

1998 • 6 citations

Solubilization, reconstitution and molecular properties of the triiodothyronine transport protein from rat erythrocyte membranes

1996 • 4 citations

Active transport of L-tri-iodothyronine through the red cell plasma membrane—true or false?

1987 • 4 citations

Thyroid hormone efflux from placental tissue is not stimulated during cell volume regulation

1997 • 4 citations

The uptake of thyroxine and tri‐iodothyronine by perfused hearts

1969 • 4 citations

Internalization of triiodothyronine-bovine serum albumin-colloidal gold complexes in human peripheral leukocytes

1987 • 4 citations

[Effects of specific protein support of thyroxin on its cellular penetration].

1958 • 4 citations

Differences in cellular transport of tri-iodothyronine and thyroxine: cell cycle-dependent alteration of tri-iodothyronine uptake

1995 • 4 citations

Uptake of L-Triiodothyronine Sulphate by Human Choriocarcinoma Cell Line, JAr

1999 • 4 citations

Uptake of Reverse T 3 in the Human Choriocarcinoma Cell Line, JAr

1999 • 2 citations

Triiodothyronine uptake by the isolated rat heart.

1998 • 2 citations

Modulation of thyroxine uptake and efflux in vitro by temelastine and phenobarbital in cultured hepatocytes from different species, in relation to toxicological effects on the thyroid gland

1994 • 2 citations