Factors influencing GAP-43 gene expression in PC12 pheochromocytoma cells

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor.

1976 • 5,526 citations

STEROID RECEPTOR REGULATED TRANSCRIPTION OF SPECIFIC GENES AND GENE NETWORKS

1985 • 1,911 citations

A Nerve Growth Factor-Induced Gene Encodes a Possible Transcriptional Regulatory Factor

1987 • 1,217 citations

Axonal Growth-Associated Proteins

1989 • 1,118 citations

Nerve growth factor and epidermal growth factor induce rapid transient changes in proto-oncogene transcription in PC12 cells.

1985 • 888 citations

Fibroblast growth factor promotes survival of dissociated hippocampal neurons and enhances neurite extension.

1986 • 741 citations

PC12 Pheochromocytoma Cultures in Neurobiological Research

1982 • 728 citations

Basic fibroblast growth factor supports the survival of cerebral cortical neurons in primary culture.

1986 • 696 citations

Nerve growth factor induces a gene homologous to the glucocorticoid receptor gene

1988 • 661 citations

A membrane phosphoprotein associated with neural development, axonal regeneration, phospholipid metabolism, and synaptic plasticity

1987 • 543 citations

Negative Regulation by Glucocorticoids Through Interference with a cAMP Responsive Enhancer

1988 • 502 citations

A protein associated with axon growth, GAP-43, is widely distributed and developmentally regulated in rat CNS

1986 • 435 citations

Environmental influences in the development of neural crest derivatives: glucocorticoids, growth factors, and chromaffin cell plasticity

1985 • 406 citations

Induction of the proto-oncogene fos by nerve growth factor.

1985 • 359 citations

Primary structure and transcriptional regulation of GAP-43, a protein associated with nerve growth

1987 • 358 citations

The effect of fibroblast growth factor on PC12 cells

1985 • 270 citations

Identification and characterization of mRNAs regulated by nerve growth factor in PC12 cells.

1987 • 267 citations

Nerve growth factor receptors on PC12 cells: ligand-induced conversion from low- to high-affinity states.

1980 • 255 citations

A nerve growth factor-regulated messenger RNA encodes a new intermediate filament protein.

1988 • 232 citations

Nerve growth factor rapidly induces c-fos mRNA in PC12 rat pheochromocytoma cells.

1986 • 220 citations

Specific changes in rapidly transported proteins during regeneration of the goldfish optic nerve

1981 • 211 citations

Down regulation of protein kinase C in neuronal cells: effects on neurotransmitter release

1987 • 204 citations

Dual regulation of GAP-43 gene expression by nerve growth factor and glucocorticoids.

1988 • 181 citations

Heparin modulation of the neurotropic effects of acidic and basic fibroblast growth factors and nerve growth factor on PC12 cells

1987 • 163 citations

Transcriptional and post-transcriptional effects of nerve growth factor on expression of the three neurofilament subunits in PC-12 cells.

1988 • 153 citations

Selective increase in phosphorylation of a 47-kDa protein (F1) directly related to long-term potentiation

1985 • 152 citations

The neuronal growth-associated protein GAP-43 (B-50, F1): neuronal specificity, developmental regulation and regional distribution of the human and rat mRNAs

1987 • 151 citations

Ionic responses and growth stimulation induced by nerve growth factor and epidermal growth factor in rat pheochromocytoma (PC12) cells.

1983 • 150 citations

The induction of a neural-specific gene, SCG10, by nerve growth factor in PC12 cells is transcriptional, protein synthesis dependent, and glucocorticoid inhibitable

1988 • 148 citations

Light-microscopic immunolocalization of the growth- and plasticity-associated protein GAP-43 in the developing rat brain

1988 • 147 citations

Nerve growth factor in mouse saliva. Rapid isolation procedures for and characterization of 7 S nerve growth factor

1978 • 138 citations

Steroid Receptor Regulated Transcription of Specific Genes and Gene Networks

1985 • 122 citations

B-50 phosphorylation and polyphosphoinositide metabolism in nerve growth cone membranes

1988 • 119 citations

Clonal variants of PC12 pheochromocytoma cells with defects in cAMP-dependent protein kinases induce ornithine decarboxylase in response to nerve growth factor but not to adenosine agonists.

1985 • 113 citations

Pro‐opiomelanocortin gene: A model for negative regulation of transcription by glucocorticoids

1987 • 104 citations

Differential inhibition of nerve growth factor and epidermal growth factor effects on the PC12 pheochromocytoma line.

1984 • 102 citations

Nerve growth factor rapidly induces ornithine decarboxylase mRNA in PC12 rat pheochromocytoma cells.

1985 • 99 citations

The neurite-promoting effect of fibroblast growth factor on PC12 cells

1983 • 88 citations

Synthesis of a growth-associated protein by embryonic rat cerebrocortical neurons in vitro

1986 • 79 citations

Primary structure of the neuron-specific phosphoprotein B-50 is identical to growth-associated protein GAP-43

1987 • 76 citations

Evidence for the coidentification of GAP-43, a growth-associated protein, and F1, a plasticity-associated protein

1987 • 75 citations

Fast axonally transported proteins in regenerating goldfish optic axons

1987 • 75 citations

Identification and Characterization of mRnas Regulated by Nerve Growth Factor in PC12 Cells

1987 • 67 citations

Axonal Growth-Associated Proteins

1989 • 62 citations

Tumor promoter modulation of epidermal growth factor‐ and nerve growth factor‐induced adhesion and growth factor binding of PC‐12 pheochromocytoma cells

1980 • 58 citations

Nerve growth factor enhances the level of the protein kinase C substrate B-50 in pheochromocytoma PC12 cells

1986 • 48 citations

Nerve growth factor rapidly stimulates arachidonate metabolism in PC12 cells: Potential involvement in nerve fiber growth

1988 • 41 citations

Serum‐ and substratum‐dependent modulation of neuritic growth

1983 • 34 citations

Decreased levels of nerve growth factor receptor on dexamethasone‐treated PC12 cells

1988 • 32 citations

Axonal and Glial Proteins Associated with Development and Response to Injury in the Rat and Goldfish Optic Nerve

1986 • 32 citations

Nerve Growth Factor Regulates Gene Expression by Several Distinct Mechanisms

1989 • 26 citations

Nerve Growth Factor Potentiates the Hormone‐Stimulated Intracellular Accumulation of Inositol Phosphates and Ca²⁺ in Rat PC12 Pheochromocytoma Cells: Comparison with the Effect of Epidermal Growth Factor

1989 • 23 citations