Inhibition of Mammalian Mitochondrial Protein Synthesis by Oxazolidinones

Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically

2000 • 16,578 citations

Tetracycline Antibiotics: Mode of Action, Applications, Molecular Biology, and Epidemiology of Bacterial Resistance

2001 • 4,038 citations

Substituent Effects on the Antibacterial Activity of Nitrogen−Carbon-Linked (Azolylphenyl)oxazolidinones with Expanded Activity Against the Fastidious Gram-Negative Organisms Haemophilus influenzae and Moraxella catarrhalis

2000 • 715 citations

Synthesis and Antibacterial Activity of U-100592 and U-100766, Two Oxazolidinone Antibacterial Agents for the Potential Treatment of Multidrug-Resistant Gram-Positive Bacterial Infections

1996 • 559 citations

Oxazolidinone Structure–Activity Relationships Leading to Linezolid

2003 • 509 citations

Hematologic Effects of Linezolid: Summary of Clinical Experience

2002 • 432 citations

The oxazolidinone eperezolid binds to the 50S ribosomal subunit and competes with binding of chloramphenicol and lincomycin

1997 • 257 citations

Peripheral neuropathy associated with prolonged use of linezolid

2004 • 240 citations

Identification of a Novel Oxazolidinone (U-100480) with Potent Antimycobacterial Activity

1996 • 232 citations

Activities of Several Novel Oxazolidinones against Mycobacterium tuberculosis in a Murine Model

1999 • 232 citations

Comparative Safety of Tetracycline, Minocycline, and Doxycycline

1997 • 211 citations

Penetration of linezolid into bone, fat, muscle and haematoma of patients undergoing routine hip replacement

2002 • 187 citations

Linezolid-Associated Toxic Optic Neuropathy: A Report of 2 Cases

2003 • 167 citations

Cross-linking in the Living Cell Locates the Site of Action of Oxazolidinone Antibiotics

2003 • 146 citations

Oxazolidinone Antibacterial Agents: A Critical Review

2003 • 140 citations

Structural basis for selectivity and toxicity of ribosomal antibiotics

2001 • 136 citations

Oxazolidinone Antibiotics Target the P Site onEscherichiacoliRibosomes

2002 • 129 citations

Hematologic Effects of Antimicrobials: Focus on the Oxazolidinone Linezolid

2001 • 128 citations

Chloramphenicol toxicity: 25 years of research.

1989 • 106 citations

Identification of Phenylisoxazolines as Novel and Viable Antibacterial Agents Active against Gram-Positive Pathogens

2002 • 85 citations

Arrest of the proliferation of renal and prostate carcinomas of human origin by inhibition of mitochondrial protein synthesis.

1986 • 75 citations

Novel oxazolidinone–quinolone hybrid antimicrobials

2003 • 68 citations

Ciprofloxacin does not inhibit mitochondrial functions but other antibiotics do

1990 • 65 citations

The mitochondrial genetic system as a target for chemotherapy: Tetracyclines as cytostatics

1984 • 63 citations

The synthesis and biological evaluation of a novel series of antimicrobials of the oxazolidinone class

2002 • 59 citations

¹ H Nuclear Magnetic Resonance Study of Oxazolidinone Binding to Bacterial Ribosomes

2002 • 58 citations

THE DRAMBALLET STUDIO

1996 • 54 citations

Antipneumococcal and Antistaphylococcal Activities of Ranbezolid (RBX 7644), a New Oxazolidinone, Compared to Those of Other Agents

2003 • 50 citations

Tissue distribution and effects on mitochondrial protein synthesis of tetracyclines after prolonged continuous intravenous administration to rats

1981 • 49 citations

AZD2563, a novel oxazolidinone: definition of antibacterial spectrum, assessment of bactericidal potential and the impact of miscellaneous factors on activity in vitro

2004 • 46 citations

Isolation and incubation conditions to study heart mitochondrial protein synthesis

1990 • 41 citations

Haemotoxicity of thiamphenicol in the BALB/c mouse and Wistar Hanover rat

2002 • 40 citations

Synthesis and antibacterial activity of pyrroloaryl-substituted oxazolidinones

2003 • 39 citations

Impairment of liver regeneration during inhibition of mitochondrial protein synthesis by oxytetracycline

1983 • 28 citations

Chloramphenicol

1986 • 23 citations

Chloramphenicol: what we have learned in the last decade.

1986 • 22 citations

Mitochondrial metabolism in normal, myeloid, and erythroid hyperplastic rabbit bone marrow: Effect of chloramphenicol

1980 • 18 citations

In Vitro and In Vivo Activities of DA-7867, a New Oxazolidinone, against Aerobic Gram-Positive Bacteria

2005 • 8 citations

The Distribution and Fate of ¹⁴C‐Chloramphenicol in the New‐born Pig

1982 • 7 citations

Absorption, distribution, metabolism and excretion of a new,¹⁴C-labelled oxazolidinone MAO-A inhibitor in rat and dog

1997 • 5 citations