Induction of Mammary Gland Development in Estrogen Receptor-α Knockout Mice

The Physiology of Reproduction

1988 • 7,765 citations

Estrogen Receptor Null Mice: What Have We Learned and Where Will They Lead Us?

1999 • 1,965 citations

Prolactin (PRL) and Its Receptor: Actions, Signal Transduction Pathways and Phenotypes Observed in PRL Receptor Knockout Mice

1998 • 1,846 citations

Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities.

1995 • 1,834 citations

Generation and reproductive phenotypes of mice lacking estrogen receptor β

1998 • 1,680 citations

Stat5a is mandatory for adult mammary gland development and lactogenesis.

1997 • 1,106 citations

Cyclin D1 provides a link between development and oncogenesis in the retina and breast

1995 • 1,017 citations

Tissue Distribution and Quantitative Analysis of Estrogen Receptor-α (ERα) and Estrogen Receptor-β (ERβ) Messenger Ribonucleic Acid in the Wild-Type and ERα-Knockout Mouse

1997 • 968 citations

Hormonal Control of Gene Expression in the Ovary

1994 • 843 citations

Null mutation of the prolactin receptor gene produces multiple reproductive defects in the mouse.

1997 • 797 citations

Mice lacking cyclin D1 are small and show defects in eye and mammary gland development.

1995 • 681 citations

Defective mammopoiesis, but normal hematopoiesis, in mice with a targeted disruption of the prolactin gene

1997 • 647 citations

Postnatal Sex Reversal of the Ovaries in Mice Lacking Estrogen Receptors α and β

1999 • 583 citations

Analysis of transcription and estrogen insensitivity in the female mouse after targeted disruption of the estrogen receptor gene.

1995 • 428 citations

The Mammary gland : development, regulation, and function

1987 • 396 citations

Estrogen receptor gene disruption: molecular characterization and experimental and clinical phenotypes.

1996 • 371 citations

The Estrogen Receptor Enhances AP-1 Activity by Two Distinct Mechanisms with Different Requirements for Receptor Transactivation Functions

1999 • 369 citations

Estrogen receptors α and β in the rodent mammary gland

2000 • 357 citations

Physiology of Reproduction.

1972 • 354 citations

Mammary gland development and tumorigenesis in estrogen receptor knockout mice.

1997 • 354 citations

Prolactin Controls Mammary Gland Development via Direct and Indirect Mechanisms

1999 • 333 citations

Targeted overexpression of luteinizing hormone in transgenic mice leads to infertility, polycystic ovaries, and ovarian tumors.

1995 • 324 citations

Endocrine Control of Mammary-Gland Development and Function in the C3H/He Crgl Mouse<xref ref-type="fn" rid="FN1">2</xref>

1958 • 281 citations

The hormonal control of mammary growth and lactation.

1958 • 267 citations

Postnatal Development of the Rodent Mammary Gland

1987 • 266 citations

Lactoferrin expression in the mouse reproductive tract during the natural estrous cycle: correlation with circulating estradiol and progesterone.

1992 • 253 citations

Identification of an estrogen-responsive element from the 5'-flanking region of the rat prolactin gene.

1987 • 231 citations

Targeted Disruption of the Estrogen Receptor-α Gene in Female Mice: Characterization of Ovarian Responses and Phenotype in the Adult*

1999 • 225 citations

Regulation of Mammary Epithelial Cell Growth in Mice and Rats*

1990 • 211 citations

Direct action of 17 beta-estradiol on mouse mammary ducts analyzed by sustained release implants and steroid autoradiography.

1987 • 196 citations

Role of Estrogen Receptor-α in the Anterior Pituitary Gland

1997 • 193 citations

Identification of multiple, widely spaced estrogen-responsive regions in the rat progesterone receptor gene.

1994 • 191 citations

Analysis of transcription and estrogen insensitivity in the female mouse after targeted disruption of the estrogen receptor gene

1995 • 187 citations

Effects of Castration and Chronic Steroid Treatments on Hypothalamic Gonadotropin-Releasing Hormone Content and Pituitary Gonadotropins in Male Wild-Type and Estrogen Receptor-α Knockout Mice

1998 • 168 citations

Estrogenic responses in estrogen receptor-α deficient mice reveal a distinct estrogen signaling pathway

1997 • 164 citations

Prolactin secretion and its control

1994 • 149 citations

Mammary gland growth and development from the postnatal period to postmenopause: ovarian steroid receptor ontogeny and regulation in the mouse.

1998 • 144 citations

A mouse mammary tumor virus-Wnt-1 transgene induces mammary gland hyperplasia and tumorigenesis in mice lacking estrogen receptor-alpha.

1999 • 141 citations

Receptor-Associated Resistance to Growth Hormone-Releasing Factor in Dwarf "Little" Mice

1986 • 133 citations

Functional Analysis of a Novel Estrogen Receptor-β Isoform

1999 • 131 citations

Essential role of endogenous estrogen in directly stimulating mammary growth demonstrated by implants containing pure antiestrogens.

1994 • 128 citations

Prolactin and mammary gland development.

1999 • 125 citations

Prevention of the Polycystic Ovarian Phenotype and Characterization of Ovulatory Capacity in the Estrogen Receptor-α Knockout Mouse

1999 • 123 citations

Developmental Regulation of Murine Mammary Progesterone Receptor Gene Expression*

1990 • 113 citations

Early mammary development: growth hormone and IGF-1.

1997 • 104 citations

EM-800, a Novel Antiestrogen, Acts as a Pure Antagonist of the Transcriptional Functions of Estrogen Receptors α and β*

1998 • 100 citations

Synergistic interaction of transforming growth factor alpha and c-myc in mouse mammary and salivary gland tumorigenesis.

1995 • 89 citations

Multiple Pit-1-binding sites facilitate estrogen responsiveness of the prolactin gene.

1994 • 80 citations

Differential Spatiotemporal Regulation of Lactoferrin and Progesterone Receptor Genes in the Mouse Uterus by Primary Estrogen, Catechol Estrogen, and Xenoestrogen¹

1998 • 77 citations

Differential regulation by estrogens of growth and prolactin synthesis in pituitary cells suggests that only a small pool of estrogen receptors is required for growth

1998 • 76 citations

ONTOGENY AND CONTROL OF PROLACTIN RECEPTORS IN THE MAMMARY GLAND AND LIVER OF VIRGIN, PREGNANT AND LACTATING RATS

1979 • 76 citations

Plasma Prolactin and Progesterone during the Estrous Cycle in the Mouse

1976 • 71 citations

Progesterone signaling and mammary gland morphogenesis.

1999 • 70 citations

Ectopic Pituitary Grafts in Mice: Hormone Levels, Effects on Fertility, and the Development of Adenomyosis Uteri, Prolactinomas, and Mammary Carcinomas*

1985 • 65 citations

Prolactin and Growth Hormone Levels in Different Inbred Strains of Mice: Patterns in Association with Estrous Cycle, Time of Day, and Perphenazine Stimulation

1975 • 62 citations

Murine Progesterone Receptor Expression in Proliferating Mammary Epithelial Cells During Normal Pubertal Development and Adult Estrous Cycle: Association with ERα and ERβ Status

1999 • 54 citations

Kinetics of mammary epithelial cell proliferation in pituitary isografted BALB/c mice

1993 • 48 citations

Mechanisms of prolactin receptor regulation in mammary gland

1993 • 46 citations

Developmental and Physiological Effects of Estrogen Receptor Gene Disruption in Mice

1997 • 45 citations

Growth Factors in Mammary Gland Development and Function

1987 • 36 citations

Prolactin

1987 • 22 citations

Interrelationship between Prolactin and Progesterone in Normal Mammary Gland Growth in SHN Virgin Mice

2009 • 19 citations

Influence of bromoergocryptine on estrogen-modulated prolactin receptors of mouse mammary gland

1978 • 19 citations

Mammary gland development during pregnancy in the dwarf mouse mutant, little

1979 • 17 citations

Bioactivity of Serum and Pituitary Prolactin during the Rat Estrous Cycle

1986 • 17 citations

Interrelationship between Pituitary and Ovarian Hormones in Normal and Neoplastic Growth of Mammary Glands of Mice^a

1986 • 13 citations

Deleted Work

1955 • 0 citations