Genetic heterogeneity of single disseminated tumour cells in minimal residual cancer

Cluster analysis and display of genome-wide expression patterns

1998 • 16,410 citations

The fundamental role of epigenetic events in cancer

2002 • 5,532 citations

Genetic instabilities in human cancers

1998 • 4,165 citations

Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis.

1994 • 3,536 citations

Comparative Genomic Hybridization for Molecular Cytogenetic Analysis of Solid Tumors

1992 • 3,344 citations

The IARC TP53 database: New online mutation analysis and recommendations to users

2002 • 1,248 citations

Cytokeratin-Positive Cells in the Bone Marrow and Survival of Patients with Stage I, II, or III Breast Cancer

2000 • 927 citations

Annual Report to the Nation on the status of cancer, 1973–1999, featuring implications of age and aging on U.S. cancer burden

2002 • 896 citations

A Mutator Phenotype in Cancer 1

2001 • 675 citations

Prognostic significance of micrometastatic tumour cells in bone marrow of colorectal cancer patients

1992 • 563 citations

Detection and Clinical Importance of Micrometastatic Disease

1999 • 505 citations

Comparative genomic hybridization, loss of heterozygosity, and DNA sequence analysis of single cells

1999 • 449 citations

Lack of Effect of Adjuvant Chemotherapy on the Elimination of Single Dormant Tumor Cells in Bone Marrow of High-Risk Breast Cancer Patients

2000 • 387 citations

Prognostic Value of Immunohistochemically Identifiable Tumor Cells in Lymph Nodes of Patients with Completely Resected Esophageal Cancer

1997 • 370 citations

Micrometastatic cancer cells in bone marrow: in vitro detection with anti-cytokeratin and in vivo labeling with anti-17-1A monoclonal antibodies.

1987 • 316 citations

Frequency and prognostic significance of isolated tumour cells in bone marrow of patients with non-small-cell lung cancer without overt metastases

1996 • 314 citations

An oncogenic form of p53 confers a dominant, gain-of-function phenotype that disrupts spindle checkpoint control

1998 • 241 citations

Prognostic significance of bone marrow micrometastases in patients with gastric cancer.

1996 • 195 citations

Immunohistochemical assessment of individual tumor cells in lymph nodes of patients with non-small-cell lung cancer.

1994 • 183 citations

Genetic divergence in the clonal evolution of breast cancer.

1996 • 164 citations

Precise microdissection of human prostate cancers reveals genotypic heterogeneity.

1998 • 159 citations

Heterogeneity in intratumor distribution of p53 mutations in human prostate cancer.

1995 • 120 citations

Cytogenetic analysis of pancreatic carcinomas: Intratumor heterogeneity and nonrandom pattern of chromosome aberrations

1998 • 116 citations

DISSEMINATED CYTOKERATIN POSITIVE TUMOR CELLS IN THE BONE MARROW OF PATIENTS WITH PROSTATE CANCER: DETECTION AND PROGNOSTIC VALUE

2001 • 100 citations

Adjuvant therapy of colon cancer

2001 • 82 citations

Primary human prostate cancer cells harboring p53 mutations are clonally expanded in metastases.

1997 • 78 citations

Cytogenetic comparison of primary tumors and lymph node metastases in breast cancer patients

1998 • 55 citations

Epithelial cells in bone marrow of oesophageal cancer patients: a significant prognostic factor in multivariate analysis

2000 • 54 citations

Cytogenetic polyclonality in tumors of the breast

1997 • 54 citations

Cytokeratin-Positive Cells in the Bone Marrow and Survival of Patients with Stage I, II, or III Breast Cancer

2000 • 47 citations

Adjuvant and neoadjuvant therapy in prostate cancer

2001 • 36 citations

Adjuvant and neoadjuvant treatment of breast cancer

2001 • 29 citations

The biology and analysis of single disseminated tumour cells

2000 • 28 citations

Introduction: The evolution of early systemic therapy

2001 • 1 citations