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Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

1998 • 14,674 citations

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

1993 • 12,238 citations

The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

2000 • 4,834 citations

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1977 • 3,432 citations

The Genome of Drosophila Melanogaster

1992 • 3,126 citations

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1994 • 3,057 citations

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1927 • 2,909 citations

A Cellular Function for the RNA-Interference Enzyme Dicer in the Maturation of the let-7 Small Temporal RNA

2001 • 2,623 citations

Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA

2000 • 2,422 citations

Drosophila — A Practical Approach

1987 • 1,888 citations

Genes and Mechanisms Related to RNA Interference Regulate Expression of the Small Temporal RNAs that Control C. elegans Developmental Timing

2001 • 1,847 citations

The lin-4 Regulatory RNA Controls Developmental Timing in Caenorhabditis elegans by Blocking LIN-14 Protein Synthesis after the Initiation of Translation

1999 • 1,174 citations

Functional ecdysone receptor is the product of EcR and Ultraspiracle genes

1993 • 936 citations

The Cold Shock Domain Protein LIN-28 Controls Developmental Timing in C. elegans and Is Regulated by the lin-4 RNA

1997 • 844 citations

Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways

2000 • 832 citations

The lin-41 RBCC Gene Acts in the C. elegans Heterochronic Pathway between the let-7 Regulatory RNA and the LIN-29 Transcription Factor

2000 • 761 citations

Temporal Control of Puffing Activity in Polytene Chromosomes

1974 • 632 citations

Heterodimerization of the Drosophila ecdysone receptor with retinoid X receptor and ultraspiracle

1993 • 519 citations

The E75 ecdysone-inducible gene responsible for the 75B early puff in Drosophila encodes two new members of the steroid receptor superfamily.

1990 • 483 citations

Flies on steroids — Drosophila metamorphosis and the mechanisms of steroid hormone action

1996 • 470 citations

The Drosophila Broad-Complex encodes a family of related proteins containing zinc fingers.

1991 • 440 citations

daf-12encodes a nuclear receptor that regulates the dauer diapause and developmental age inC. elegans

2000 • 417 citations

The Drosophila 74EF early puff contains E74, a complex ecdysone-inducible gene that encodes two ets-related proteins

1990 • 417 citations

A hierarchy of regulatory genes controls a larva-to-adult developmental switch in C. elegans

1989 • 356 citations

From embryogenesis to metamorphosis: The regulation and function of drosophila nuclear receptor superfamily members

1995 • 347 citations

Drosophila Brain Tumor is a translational repressor

2001 • 319 citations

Roles of ecdysone in Drosophila development

1977 • 278 citations

Spatial and temporal patterns of E74 transcription during Drosophila development

1990 • 254 citations

A bulged lin-4/lin-14 RNA duplex is sufficient for Caenorhabditis elegans lin-14 temporal gradient formation.

1996 • 235 citations

The Caenorhabditis elegans heterochronic gene lin-14 encodes a nuclear protein that forms a temporal developmental switch

1989 • 227 citations

The Drosophila Broad-Complex plays a key role in controlling ecdysone-regulated gene expression at the onset of metamorphosis

1993 • 209 citations

The radioimmune assay of ecdysteroid titres in drosophila melanogaster

1981 • 186 citations

The Broad-Complex directly controls a tissue-specific response to the steroid hormone ecdysone at the onset of Drosophila metamorphosis.

1994 • 175 citations

Nuclear receptors in nematodes: themes and variations

2001 • 155 citations

Chapter 29 Methods for Quantitative Analysis of Transcription in Larvae and Prepupae

1994 • 155 citations

A novel repeat domain that is often associated with RING finger and B-box motifs

1998 • 154 citations

Control of developmental timing in Caenorhabditis elegans

2000 • 152 citations

A Switch inBroad-ComplexZinc-Finger Isoform Expression Is Regulated Posttranscriptionally during the Metamorphosis ofDrosophilaImaginal Discs

1996 • 147 citations

Mutations in the β-propeller domain of the Drosophila brain tumor (brat) protein induce neoplasm in the larval brain

2000 • 125 citations

TEMPORAL PATTERN FORMATION BY HETEROCHRONIC GENES

1997 • 115 citations

Isolation, regulation, and DNA-binding properties of three Drosophila nuclear hormone receptor superfamily members.

1995 • 114 citations

Cytogenetic analysis of the 2B3-4-2B11 Region of the X chromosome of Drosophila melanogaster

1981 • 104 citations

TheDrosophila Broad-ComplexEarly Gene Directly Regulates Late Gene Transcription during the Ecdysone-Induced Puffing Cascade

1996 • 89 citations

Genetic Studies of mei-P26 Reveal a Link Between the Processes That Control Germ Cell Proliferation in Both Sexes and Those That Control Meiotic Exchange in Drosophila

2000 • 82 citations

Identification of Immune System and Response Genes, and Novel Mutations Causing Melanotic Tumor Formation in Drosophila melanogaster

1996 • 82 citations

Heterochronic genes and the temporal control of C. elegans development

1994 • 74 citations

Steroid and high-temperature induction of the small heat-shock protein genes in Drosophila

1984 • 68 citations

Molecular analysis of a steroid-induced regulatory hierarchy: the Drosophila E74A protein directly regulates L71-6 transcription.

1995 • 56 citations

The Ecdysone Regulatory Cascades in Drosophila

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The Effects of Ecdysteroid Hormones on Drosophila Melanogaster Cell Lines

1981 • 50 citations

Cytogenetic analysis of the 2B3-4 ? 2B11 region of the X chromosome of Drosophila melanogaster

1982 • 41 citations

The Broad-Complex Gene Is a Tissue-Specific Modulator of the Ecdysone Response of the Drosophila hsp23 Gene

1996 • 28 citations

Selective binding of Drosophila BR-C isoforms to a distal regulatory element in the hsp23 promoter

2001 • 26 citations

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1975 • 9 citations