PHOTODYNAMIC LIPID PEROXIDATION IN BIOLOGICAL SYSTEMS

Free radicals in biology and medicine

1985 • 2,999 citations

Identification of singlet oxygen as the cytotoxic agent in photoinactivation of a murine tumor.

1976 • 1,430 citations

Superoxide, hydrogen peroxide, and singlet oxygen in lipid peroxidation by a xanthine oxidase system.

1975 • 969 citations

Superoxide‐dependent production of hydroxyl radical catalyzed by iron—EDTA complex

1978 • 876 citations

Formation of a thiobarbituric‐acid‐reactive substance from deoxyribose in the presence of iron salts

1981 • 830 citations

Photosensitized Oxidation and Singlet Oxygen: Consequences in Biological Systems

1976 • 827 citations

PHOTOSENSITIZERS: THERAPY AND DETECTION OF MALIGNANT TUMORS

1987 • 778 citations

Porphyrin localization and treatment of tumors

1985 • 633 citations

Oxygen and oxy‐radicals in chemistry and biology

1982 • 557 citations

Mechanisms of lipid peroxidation

1985 • 542 citations

Lipid Peroxidation: Mechanisms, Analysis, Enzymology and Biological Relevance

1985 • 520 citations

A study of the reactivity of HO2/O2- with unsaturated fatty acids.

1983 • 519 citations

Protective action of phospholipid hydroperoxide glutathione peroxidase against membrane-damaging lipid peroxidation. In situ reduction of phospholipid and cholesterol hydroperoxides.

1990 • 516 citations

Cholesterol Autoxidation

1981 • 492 citations

Characterization and quantification of red cell lipids in normal man

1964 • 473 citations

Chemistry of free radical and singlet oxidation of lipids

1984 • 442 citations

A new role for phospholipase A2: protection of membranes from lipid peroxidation damage

1987 • 428 citations

Lifetime of oxygen (O2(1.DELTA.g)) in liquid water as determined by time-resolved infrared luminescence measurements

1982 • 407 citations

The Role of Free Radical Reactions in Biological Systems

1976 • 374 citations

POTENTIAL INVOLVEMENT OF FREE RADICAL REACTIONS IN ULTRAVIOLET LIGHT‐MEDIATED CUTANEOUS DAMAGE*

1987 • 344 citations

Lipid oxidation: Biologic effects and antioxidants—A review

1980 • 308 citations

Self-reaction of sec-butylperoxy radicals. Confirmation of the Russell mechanism

1968 • 288 citations

PHOTOMODIFICATION OF BIOLOGICAL MEMBRANES WITH EMPHASIS ON SINGLET OXYGEN MECHANISMS

1987 • 275 citations

LASER FLASH PHOTOKINETIC STUDIES OF ROSE BENGAL SENSITIZED PHOTODYNAMIC INTERACTIONS OF NUCLEOTIDES AND DNA

1987 • 267 citations

HEMATOPORPHYRIN and HPD: PHOTOPHYSICS, PHOTOCHEMISTRY and PHOTOTHERAPY

1984 • 263 citations

[26] Low-level chemiluminescence as an indicator of singlet molecular oxygen in biological systems

1984 • 231 citations

The mechanism of olefin epoxidation by oxo-iron porphyrins. Direct observation of an intermediate

1986 • 189 citations

PROTECTIVE ACTION OF CAROTENOID PIGMENTS AGAINST PHOTODYNAMIC DAMAGE TO LIPOSOMES*

1973 • 179 citations

A spectrophotometric method for the determination of lipid hydroperoxides

1979 • 174 citations

Cytotoxicity from Coupled Redox Cycling of Autoxidizing Xenobiotics and Metals: A Selective Critical Review and Commentary on Work‐in‐Progress

1984 • 170 citations

An investigation into the role of hydroxyl radical in xanthine oxidase-dependent lipid peroxidation

1982 • 159 citations

Damaging effects of oxygen radicals on resealed erythrocyte ghosts.

1984 • 154 citations

Photodynamic action of merocyanine 540 on artificial and natural cell membranes: involvement of singlet molecular oxygen.

1987 • 148 citations

Products formed by photosensitized oxidation of unsaturated fatty acid esters

1977 • 142 citations

BIOLOGICAL ACTIVITIES OF PHTHALOCYANINES—IV. TYPE II SENSITIZED PHOTOOXIDATION OF L‐TRYPTOPHAN AND CHOLESTEROL BY SULFONATED METALLO PHTHALOCYANINES

1986 • 139 citations

The mechanism of liver microsomal lipid peroxidation

1975 • 136 citations

Photo‐sensitized oxidation of unsaturated fatty acid methyl esters. The identification of different pathways

1977 • 134 citations

Zur photosensibilisierten Autoxydation der Steroide. Darstellung von Steroid‐Hydroperoxyden Mittels Phototoxischer Photosensibilisatoren

1957 • 130 citations

TYPE I AND TYPE II MECHANISMS IN THE PHOTOSENSITIZED LYSIS OF PHOSPHATIDYLCHOLINE LIPOSOMES BY HEMATOPORPHYRIN

1982 • 130 citations

Cholesterol autoxidation in phospholipid membrane bilayers

1987 • 127 citations

Sterol metabolism. XXIII. Cholesterol oxidation by radiation-induced processes

1973 • 123 citations

Reactivity of singlet molecular oxygen with cholesterol in a phospholipid membrane matrix. A model for oxidative damage of membranes

1977 • 112 citations

Singlet Oxygen Formation Detected by Low-Level Chemiluminescence during Enzymatic Reduction of Prostaglandin G₂to H₂

1983 • 109 citations

The effect of cholesterol and other intercalated amphipaths on the contour and stability of the isolated red cell membrane.

1980 • 107 citations

MECHANISMS OF PHOTOSENSITIZATION

1983 • 106 citations

[24] Reaction of ·OH

1984 • 98 citations

[3] Characterization of singlet oxygen

1984 • 96 citations

Reactivity of Phospholipid Hydroperoxide Glutathione Peroxidase with Membrane and Lipoprotein Lipid Hydroperoxides

1991 • 91 citations

PROOXIDANT and ANTIOXIDANT EFFECTS OF ASCORBATE ON PHOTOSENSITIZED PEROXIDATION OF LIPIDS IN ERYTHROCYTE MEMBRANES

1985 • 73 citations

Superoxide and hydrogen peroxide-dependent lipid peroxidation in intact and Triton-dispersed erythrocyte membranes

1984 • 72 citations

Role of lipid peroxidation in hematoporphyrin derivative-sensitized photokilling of tumor cells: protective effects of glutathione peroxidase.

1989 • 68 citations

Singlet oxygen intermediacy in the photodynamic action of membrane-bound hematoporphyrin derivative

1987 • 68 citations

Photosensitization by hematoporphyrin: ESR evidence for free radical induction in unsaturated fatty acids and for singlet oxygen production

1977 • 66 citations

The role of superoxide in xanthine oxidase-induced autooxidation of linoleic acid.

1982 • 62 citations

Photooxidation of cell membranes in the presence of hematoporphyrin derivative: reactivity of phospholipid and cholesterol hydroperoxides with glutathione peroxidase

1988 • 61 citations

FREE RADICALS FROM PHOTOREDUCTION OF HEMATOPORPHYRIN IN AQUEOUS SOLUTION

1983 • 56 citations

Superoxide, hydrogen peroxide and singlet oxygen in hematoporphyrin derivative-cysteine, -NADH and -light systems

1987 • 55 citations

Ascorbate‐enhanced lipid peroxidation in photooxidized cell membranes: Cholesterol product analysis as a probe of reaction mechanism

1988 • 53 citations

Singlet oxygen in copper‐catalyzed lipid peroxidation in erythrocyte membranes

1984 • 52 citations

Interaction between an organic hydroperoxide and an unsaturated phospholipid and α-tocopherol in model membranes

1980 • 45 citations

Enzymatic determination of membrane lipid peroxidation

1985 • 39 citations

Fluorescence lifetime of bacteriochlorophyll and reaction center photooxidation in a photosynthetic bacterium

1970 • 37 citations

Phospholipid autoxidation

1986 • 37 citations

Lipid peroxidation in erythrocyte membranes: Cholesterol product analysis in photosensitized and xanthine oxidase‐catalyzed reactions

1987 • 35 citations

Hydrogen peroxide and hydroxyl radical formation by methylene blue in the presence of ascorbic acid

1984 • 34 citations

PORPHYRIN‐SENSITIZED PHOTOREACTIONS IN THE PRESENCE OF ASCORBATE: OXIDATION OF CELL MEMBRANE LIPIDS AND HYDROXYL RADICAL TRAPS

1988 • 31 citations

Dye sensitised photo-oxidation of the methyl and phenyl esters of oleic and linoleic acids

1987 • 28 citations

RADICAL PROCESSES IN LIPIDS. SELECTIVITY OF HYDROGEN ABSTRACTION FROM LIPIDS BY BENZOPHENONE TRIPLET

1989 • 28 citations

DOES THE AEROBIC XANTHINE OXIDASE REACTION GENERATE SINGLET OXYGEN?*

1985 • 28 citations

Evidence for the production of singlet molecular oxygen from the quenching of excited states of dialkyl ketones by molecular oxygen

1979 • 26 citations

Light-stimulated formation of hydrogen peroxide and hydroxyl radical in the presence of uroporphyrin and ascorbate

1988 • 20 citations

RED CHEMILUMINESCENCE FROM RAM SEMINAL VESICLE MICROSOMES: PITFALLS IN THE USE OF SPECTRALLY RESOLVED RED CHEMILUMINESCENCE AS A TEST FOR SINGLET OXYGEN IN BIOLOGICAL SYSTEMS

1988 • 15 citations

Oxidants and Human Health

1976 • 13 citations