Linkage analysis in adenomatous polyposis coli: the use of four closely linked DNA probes in 20 UK families.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Strategies for multilocus linkage analysis in humans.

1984 • 2,600 citations

The evolution of cancer of the colon and rectum

1975 • 2,120 citations

Localization of the gene for familial adenomatous polyposis on chromosome 5

1987 • 1,386 citations

The Gene for Familial Polyposis Coli Maps to the Long Arm of Chromosome 5

1987 • 683 citations

Characterization of a panel of highly variable minisatellites cloned from human DNA

1987 • 534 citations

A genetic and clinical study of intestinal polyposis, a predisposing factor for carcinoma of the colon and rectum.

1951 • 406 citations

Report of the committee on methods of linkage analysis and reporting

1985 • 325 citations

Familial Polyposis Coli

1978 • 273 citations

Genetic Analysis of an Inherited Predisposition to Colon Cancer in a Family with a Variable Number of Adenomatous Polyps

1990 • 254 citations

Localization of the genetic defect in familial adenomatous polyposis within a small region of chromosome 5.

1988 • 196 citations

Familial Polyposis Coli

1976 • 127 citations

High frequency of APC loss in sporadic colorectal carcinoma due to breaks clustered in 5q21-22.

1989 • 117 citations

The UK Northern region genetic register for familial adenomatous polyposis coli: use of age of onset, congenital hypertrophy of the retinal pigment epithelium, and DNA markers in risk calculations.

1991 • 113 citations

Congenital hypertrophy of retinal pigment epithelium: a sign of familial adenomatous polyposis.

1989 • 85 citations

Close linkage of a highly polymorphic marker (D5S37) to familial adenomatous polyposis (FAP) and confirmation of FAP localization on chromosome 5q21-q22

1988 • 79 citations

A computer program to make linkage analysis with <scp>liped</scp> and <scp>linkage</scp> easier to perform and less prone to input errors

1988 • 74 citations

PRESYMPTOMATIC DIAGNOSIS OF FAMILIAL ADENOMATOUS POLYPOSIS BY BRIDGING DNA MARKERS

1989 • 61 citations

CpG island clones from a deletion encompassing the gene for adenomatous polyposis coli.

1989 • 43 citations

Genetic linkage map of six polymorphic DNA markers around the gene for familial adenomatous polyposis on chromosome 5.

1990 • 27 citations

Linkage analysis in familial adenomatous polyposis: Order of C11P11 (D5S71) and ?227 (D5S37) loci at the apc gene

1989 • 21 citations

An anonymous DNA segment (II227) maps to the long arm of human chromosome 5 and identifies a BstX1 polymorphism (D5S26)

1987 • 16 citations

Ozone and Acid Rain

1987 • 9 citations