Evidence against a direct role for the induction of c-jun expression in the mediation of drug-induced apoptosis in human acute leukemia cells.

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

1993 • 3,465 citations

The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation

1991 • 3,396 citations

Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species

1993 • 1,692 citations

Programmed cell death involved in the schizolysigenous formation of the secretory cavity in Citrus sinensis L. (Osbeck)

2010 • 1,629 citations

The c-fos protein interacts with c-JunAP-1 to stimulate transcription of AP-1 responsive genes

1988 • 1,352 citations

Oncogene jun encodes a sequence-specific trans- activator similar to AP-1

1988 • 940 citations

Bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line

1993 • 898 citations

Continuous c-fos expression precedes programmed cell death in vivo

1993 • 784 citations

The jun and fos protein families are both required for cell cycle progression in fibroblasts.

1991 • 442 citations

Expression and involvement of c-fos and c-jun protooncogenes in programmed cell death induced by growth factor deprivation in lymphoid cell lines.

1992 • 401 citations

Bcl-2 inhibits chemotherapy-induced apoptosis in neuroblastoma.

1994 • 280 citations

Inhibition of DNA Fragmentation in Thymocytes and Isolated Thymocyte Nuclei by Agents That Stimulate Protein Kinase C

1989 • 276 citations

Taxol induces internucleosomal DNA fragmentation associated with programmed cell death in human myeloid leukemia cells.

1993 • 273 citations

bcl-2 modulation of apoptosis induced by anticancer drugs: resistance to thymidylate stress is independent of classical resistance pathways.

1993 • 238 citations

bcl-2 protein inhibits etoposide-induced apoptosis through its effects on events subsequent to topoisomerase II-induced DNA strand breaks and their repair.

1993 • 218 citations

Induction of internucleosomal DNA fragmentation in human myeloid leukemia cells by 1-beta-D-arabinofuranosylcytosine.

1991 • 198 citations

Staurosporine is a potent inhibitor of p34cdc2 and p34cdc2-like kinases

1992 • 134 citations

Effects of bryostatin 1 and other pharmacological activators of protein kinase C on 1-[β-d-arabinofuranosyl]cytosine-induced apoptosis in HL-60 human promyelocytic leukemia cells

1994 • 86 citations

Apoptosis or Programmed Cell Death

1991 • 79 citations

Activation of the c-jun protooncogene in human myeloid leukemia cells treated with etoposide.

1991 • 74 citations

cis-Diamminedichloroplatinum(II) induces c-jun expression in human myeloid leukemia cells: potential involvement of a protein kinase C-dependent signaling pathway.

1992 • 72 citations

Camptothecin and its derivatives induce expression of the c-jun protooncogene in human myeloid leukemia cells.

1991 • 66 citations

Differential regulation of c-fos, fosB, c-jun, junB, bcl-2 and bax expression in rat skin following single or chronic ultraviolet irradiation and in vivo modulation by antisense oligodeoxynucleotide superfusion.

1994 • 63 citations

Transient mitotic phase localization of bcl-2 oncoprotein in human carcinoma cells and its possible role in prevention of apoptosis.

1994 • 58 citations

Regulation of c-jun gene expression in HL-60 leukemia cells by 1-.beta.-D-arabinofuranosylcytosine. Potential involvement of a protein kinase C dependent mechanism

1991 • 54 citations

Prolonged expression of c-jun and associated activity of the transcription factor AP-1, during apoptosis in a human leukaemic cell line.

1994 • 49 citations

Protein kinase C modulation.

1992 • 38 citations

Amplified expression of three jun family members inhibits erythroleukemia differentiation

1990 • 28 citations

Enhancement of the Antiproliferative Effect of cis-Diamminedichloroplatinum (II) and Other Antitumor Agents by Inhibitors of Enzymes Involved in Growth Factor Signal-Transduction

1991 • 8 citations