tkl is the avian homolog of the mammalian lck tyrosine protein kinase gene.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

1988 • 1,442 citations

Possible role of flanking nucleotides in recognition of the AUG initiator codon by eukaryotic ribosomes

1981 • 1,265 citations

GPI-Anchored Cell-Surface Molecules Complexed to Protein Tyrosine Kinases

1991 • 848 citations

The CD4 receptor is complexed in detergent lysates to a protein-tyrosine kinase (pp58) from human T lymphocytes.

1988 • 716 citations

Interaction of the unique N-terminal region of tyrosine kinase p56lck with cytoplasmic domains of CD4 and CD8 is mediated by cysteine motifs

1990 • 629 citations

Interaction of the IL-2 Receptor with thesrc-Family Kinase p56^lck: Identification of Novel Intermolecular Association

1991 • 576 citations

A lymphocyte-specific protein-tyrosine kinase gene is rearranged and overexpressed in the murine T cell lymphoma LSTRA

1985 • 550 citations

Peptides and Protein Phosphorylation

2018 • 525 citations

Hypomethylation of ras oncogenes in primary human cancers

1983 • 507 citations

The Ick tyrosine protein kinase interacts with the cytoplasmic tail of the CD4 glycoprotein through its unique amino-terminal domain

1989 • 362 citations

Identification of the avian homologues of mammalian CD4 and CD8 antigens.

1988 • 300 citations

Expression of a new tyrosine protein kinase is stimulated by retrovirus promoter insertion

1986 • 290 citations

Specific Expression of a Tyrosine Kinase Gene, blk , in B Lymphoid Cells

1990 • 234 citations

Engineered Metal-Binding Proteins: Purification to Protein Folding

1991 • 232 citations

Translational activation of the lck proto-oncogene

1988 • 203 citations

Expression of the lck tyrosine kinase gene in human colon carcinoma and other non-lymphoid human tumor cell lines.

1987 • 132 citations

Activation of p56lck through mutation of a regulatory carboxy-terminal tyrosine residue requires intact sites of autophosphorylation and myristylation.

1990 • 129 citations

Developmental regulation of lck gene expression in T lymphocytes.

1991 • 124 citations

Covalently bound myristate in a lymphoma tyrosine protein kinase.

1984 • 120 citations

Functional and biochemical characterizations of avian T lymphocyte antigens identified by monoclonal antibodies

1988 • 112 citations

src-related tyrosine protein kinases as signaling components in hematopoietic cells.

1990 • 109 citations

Structure and expression of Ick transcripts in human lymphoid cells

1988 • 104 citations

Post-translational alterations of the tyrosine kinase p56lck in response to activators of protein kinase C.

1988 • 103 citations

Early separation of B and T lymphocyte precursors in chick embryo.

1991 • 86 citations

Structure of the Murine lck Gene and Its Rearrangement in a Murine Lymphoma Cell Line

1988 • 86 citations

DNA sequence encoding the amino-terminal region of the human c-src protein: implications of sequence divergence among src-type kinase oncogenes.

1987 • 84 citations

Two lck Transcripts Containing Different 5′ Untranslated Regions are Present in T Cells

1987 • 63 citations

Changes in the relative abundance of type I and type II lck mRNA transcripts suggest differential promoter usage during T-cell development.

1990 • 62 citations

The lck tyrosine protein kinase.

1991 • 62 citations

Structure of the two promoters of the human lck gene: differential accumulation of two classes of lck transcripts in T cells.

1989 • 61 citations

The lymphocyte-specific tyrosine protein kinase p56lck.

1991 • 60 citations

Transcriptional activation of lck by retrovirus promoter insertion between two lymphoid-specific promoters

1988 • 56 citations

The tyrosine kinase lck is critically involved in the growth transformation of human B lymphocytes

1991 • 44 citations

Structure of the murine lck gene and its rearrangement in a murine lymphoma cell line.

1988 • 43 citations

Additional member of the protein-tyrosine kinase family: the src- and lck-related protooncogene c-tkl.

1987 • 34 citations

Structure of the human lck gene: differences in genomic organisation within src-related genes affect only N-terminal exons

1989 • 32 citations

Avian CD4 and CD8 interact with a cellular tyrosine protein kinase homologous to mammalian p56^lck

1991 • 28 citations

Src Family of Protein Tyrosine Kinases

2004 • 19 citations

The end can justify the means.

1990 • 17 citations

The sequence of chicken c-yes and p61c-yes.

1989 • 7 citations