Kinetics for the secretion of nonhelical procollagen by freshly isolated tendon cells

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Film Detection Method for Tritium‐Labelled Proteins and Nucleic Acids in Polyacrylamide Gels

1974 • 8,693 citations

Quantitative Film Detection of 3H and 14C in Polyacrylamide Gels by Fluorography

1975 • 4,693 citations

Analysis of bacteriophage T7 early RNAs and proteins on slab gels

1973 • 2,246 citations

Use of a mixture of proteinase-free collagenases for the specific assay of radioactive collagen in the presence of other proteins

1971 • 1,396 citations

Polypeptides of the tail fibres of bacteriophage T4

1971 • 956 citations

Modified procedure for the assay of H3- or C14-labeled hydroxyproline

1966 • 710 citations

The thermal transition of a non-hydroxylated form of collagen. Evidence for a role for hydroxyproline in stabilizing the triple-helix of collagen

1973 • 563 citations

General Remarks on Principles, Equipment, Reagents and Procedures

1973 • 346 citations

Synthesis and extrusion of collagen by freshly isolated cells from chick embryo tendon

1971 • 280 citations

Mechanism of the Prolyl Hydroxylase Reaction

1977 • 260 citations

Hydroxyproline content determines the denaturation temperature of chick tendon collagen

1973 • 224 citations

Time lag in the secretion of collagen by matrix-free tendon cells and inhibition of the secretory process by colchicine and vinblastine

1972 • 197 citations

Hydroxylation of Proline and the Intracellular Accumulation of a Polypeptide Precursor of Collagen

1966 • 180 citations

Affinity Column Purification of Protocollagen Proline Hydroxylase from Chick Embryos and Further Characterization of the Enzyme

1973 • 168 citations

Introduction to mathematical biology

1975 • 152 citations

Introduction to Mathematical Biology

1976 • 149 citations

Incorporation of proline analogues into collagen polypeptides Effects on the production of extracellular procollagen and on the stability of the triple-helical structure of the molecule

1974 • 134 citations

The Methodology of Connective Tissue Research

1976 • 132 citations

The stimulation of collagen secretion by ascorbate as a result of increased proline hydroxylation in chick embryo fibroblasts

1975 • 121 citations

Purification of carbon-14-labeled protocollagen and its hydroxylation by prolyl-hydroxylase

1973 • 120 citations

Effects of the stereo-configuration of the hydroxyl group in 4-hydroxyproline on the triple-helical structures formed by homogeneous peptides resembling collagen

1976 • 104 citations

Intracellular Collagen and Protocollagen from Embryonic Tendon Cells

1973 • 103 citations

Incorporation of cis-Hydroxyproline into Protocollagen and Collagen

1971 • 91 citations

Kinetics for the secretion of procollagen by freshly isolated tendon cells

1977 • 89 citations

Incorporation of 3,4-Dehydroproline into Protocollagen and Collagen

1970 • 77 citations

Interchain disulfide bonds at the COOH-terminal end of procollagen synthesized by matrix-free cells from chick embryonic tendon and cartilage

1976 • 77 citations

Effect of the proline analogue azetidine-2-carboxylic acid on collagen synthesis in vivo I. Arrest of collagen accumulation in growing chick embryos

1971 • 75 citations

INTRACELLULAR ACCUMULATION OF PROTOCOLLAGEN AND EXTRUSION OF COLLAGEN BY EMBRYONIC CARTILAGE CELLS

1968 • 75 citations

Regulation of collagen secretion by ascorbic acid in 3T3 and chick embryo fibroblasts

1972 • 72 citations

Biosynthesis of abnormal collagens with amino acid analogues. II. Inability of cartilage cells to extrude collagen polypeptides containing L-azetidine-2-carboxylic acid or cis-4-fluoro-L-proline.

1969 • 70 citations

Incorporation of cis-hydroxyproline into collagen by tendon cells. Failure of the intracellular collagen to assume a triple-helical conformation

1972 • 68 citations

Inhibition of proline and lysine hydroxylation prevents normal extrusion of collagen by 3T6 fibroblasts in culture

1971 • 67 citations

Ascorbate increases the synthesis of procollagen hydroxyproline by cultured fibroblasts from chick embryo tendons without activation or prolyl hydroxylase

1975 • 66 citations

Intracellular Hydroxylation of Non‐Helical Protocollagen to Form Triple‐Helical Procollagen and Subsequent Secretion of the Molecule

1974 • 65 citations

Biosynthesis of abnormal collagens with amino acid analogues

1969 • 61 citations

The synthesis of underhydroxylated collagen by 3T6 mouse fibroblasts in culture

1972 • 60 citations

Hydroxylation of lysyl residues in collagen by protocollagen lysyl hydroxylase in vitro

1973 • 59 citations

Segment-long-spacing aggregates and isolation of COOH-terminal peptides from type I procollagen.

1976 • 56 citations

The role of hydroxylation in the secretion of collagen by mouse fibroblasts in culture

1971 • 55 citations

Glucosylation of Galactosylhydroxylysyl Residues in Collagen in vitro by Collagen Glucosyltransferase

1975 • 51 citations

Effects of Temperature on Conformation, Hydroxylation, and Secretion of Chick Tendon Procollagen

1974 • 50 citations

Decreased thermal stability of collagens containing analogs of proline or lysine

1974 • 45 citations

Effect of L-3,4-dehydroproline on collagen synthesis and prolyl hydroxylase activity in mammalian cell cultures.

1976 • 43 citations

Retention of Nonhelical Procollagen Containing cis -Hydroxyproline in Rough Endoplasmic Reticulum

1975 • 43 citations

Partial purification and characterization of collagen galactosyltransferase from chick embryos

1976 • 42 citations

Incorporation of proline analogs into procollagen

1977 • 38 citations

Metabolism by isolated fibroblasts of abnormal collagens containing analogues of proline or lysine

1972 • 37 citations

Effect of L-azetidine-2-carboxylic acid on glycosylations of collagen in chick-embryo tendon cells

1976 • 30 citations

Procollagen polypeptides containing cis-4-hydroxy-l-proline are overglycosylated and secreted as nonhelical pro-γ-chains

1978 • 29 citations

The Formation of Collagen α Chains in the Absence of Proline Hydroxylation

1970 • 26 citations

Tracer Probes in Steady State Systems

1972 • 26 citations

Labeled antibodies to protocollagen proline hydroxylase from chick embryos for intracellular localization of the enzyme

1972 • 25 citations

Influence of α,ά-Dipyridyl on the Biosynthesis of Collagen in Organ Cultures

1974 • 24 citations

Secretion of unhydroxylated chick tendon procollagen

1975 • 16 citations

Inhibition of prolyl hydroxylase by collagen

1974 • 5 citations

Tracer Probes in Steady State Systems.

1972 • 2 citations