Pseudomonas aeruginosa Hemolytic Phospholipase C Suppresses Neutrophil Respiratory Burst Activity

Common Virulence Factors for Bacterial Pathogenicity in Plants and Animals

1995 • 1,322 citations

TNF activates NF-κB by phosphatidylcholine-specific phospholipase C-induced “Acidic” sphingomyelin breakdown

1992 • 1,058 citations

Cystic Fibrosis Airway Epithelia Fail to Kill Bacteria Because of Abnormal Airway Surface Fluid

1996 • 1,042 citations

ADP-ribosylation factor, a small GTP-dependent regulatory protein, stimulates phospholipase D activity

1993 • 900 citations

Chromosomal genetics of Pseudomonas

1979 • 721 citations

Iron and Susceptibility to Infectious Disease

1974 • 576 citations

Assembly of the phagocyte NADPH oxidase: molecular interaction of oxidase proteins

1996 • 534 citations

Dual roles of plcA in Listeria monocytogenes pathogenesis

1993 • 452 citations

Common and distinct intracellular signaling pathways in human neutrophils utilized by platelet activating factor and FMLP.

1997 • 311 citations

SYPRO Orange and SYPRO Red Protein Gel Stains: One-Step Fluorescent Staining of Denaturing Gels for Detection of Nanogram Levels of Protein

1996 • 258 citations

Molecular comparison of a nonhemolytic and a hemolytic phospholipase C from Pseudomonas aeruginosa

1990 • 164 citations

Characterization and Sequencing of a Respiratory Burst-inhibiting Acid Phosphatase from Francisella tularensis

1996 • 157 citations

Phosphorylation of the Respiratory Burst Oxidase Subunit p67 during Human Neutrophil Activation

1997 • 154 citations

Alveolar epithelial injury and pleural empyema in acute P. aeruginosa pneumonia in anesthetized rabbits

1993 • 132 citations

Requirement for posttranslational processing of Rac GTP-binding proteins for activation of human neutrophil NADPH oxidase.

1993 • 130 citations

Mutations in the hemolytic-phospholipase C operon result in decreased virulence of Pseudomonas aeruginosa PAO1 grown under phosphate-limiting conditions

1989 • 125 citations

Activation of a Mitogen-activated Protein Kinase (ERK2) by the 5-Hydroxytryptamine1A Receptor Is Sensitive Not Only to Inhibitors of Phosphatidylinositol 3-Kinase, but to an Inhibitor of Phosphatidylcholine Hydrolysis

1996 • 103 citations

Osmoprotectants and phosphate regulate expression of phospholipase C in Pseudomonas aeruginosa

1992 • 94 citations

A two-component T7 system for the overexpression of genes in Pseudomonas aeruginosa

1992 • 80 citations

Relation between Antibody Response to Pseudomonas aeruginosa Exoproteins and Colonization/Infection in Patients with Cystic Fibrosis

1984 • 79 citations

Involvement of Phosphatidylcholine-specific Phospholipase C in Platelet-derived Growth Factor-induced Activation of the Mitogen-activated Protein Kinase Pathway in Rat-1 Fibroblasts

1997 • 71 citations

Activation of MAP kinase-activated protein kinase 2 in human neutrophils after phorbol ester or fMLP peptide stimulation

1996 • 69 citations

Decreased Pulmonary Vasoreactivity in an Animal Model of ChronicPseudomonasPneumonia

1990 • 56 citations

In vivo studies with two phospholipase C fractions from Pseudomonas aeruginosa

1987 • 55 citations

In vivo and in vitro toxicity of phospholipase C from Pseudomonas aeruginosa

1992 • 54 citations

PlcR1 and PlcR2 are putative calcium-binding proteins required for secretion of the hemolytic phospholipase C of Pseudomonas aeruginosa

1997 • 47 citations

Phospholipase C and phospholipase D are activated independently of each other in chemotactic peptide-stimulated human neutrophils

1993 • 36 citations

Biological Properties of Phospholipase C Purified from a Fleecerot Isolate of Pseudomonas aeruginosa

1988 • 32 citations

XO increases neutrophil adherence to endothelial cells by a dual ICAM-1 and P-selectin-mediated mechanism

1997 • 26 citations

Relation between antibody response to pseudomonas aeruginosa exoproteins and colonization/infection in patients with cystic fibrosis

1985 • 18 citations

Deleted Work

1955 • 0 citations