Epigallocatechin-3-gallate inhibits activation of HER-2/neu and downstream signaling pathways in human head and neck and breast carcinoma cells.

Stat3 as an Oncogene

1999 • 2,770 citations

NEW EMBO MEMBERS' REVIEW: The ErbB signaling network: receptor heterodimerization in development and cancer

2000 • 2,394 citations

STATs in oncogenesis

2000 • 1,723 citations

Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells

2001 • 751 citations

Blood and urine levels of tea catechins after ingestion of different amounts of green tea by human volunteers.

1998 • 570 citations

Phase I pharmacokinetic study of tea polyphenols following single-dose administration of epigallocatechin gallate and polyphenon E.

2001 • 413 citations

Overexpression of ErbB2 in cancer and ErbB2-targeting strategies

2000 • 409 citations

STAT signaling in head and neck cancer

2000 • 374 citations

Effects of epigallocatechin-3-gallate on growth, epidermal growth factor receptor signaling pathways, gene expression, and chemosensitivity in human head and neck squamous cell carcinoma cell lines.

2001 • 318 citations

Suppression of extracellular signals and cell proliferation through EGF receptor binding by (−)-epigallocatechin gallate in human A431 epidermoid carcinoma cells

1997 • 293 citations

Combination of EGFR, HER-2/neu, and HER-3 is a stronger predictor for the outcome of oral squamous cell carcinoma than any individual family members.

1999 • 293 citations

The Anthocyanidins Cyanidin and Delphinidin Are Potent Inhibitors of the Epidermal Growth-Factor Receptor

2001 • 255 citations

Epigallocatechin‐3‐gallate decreases VEGF production in head and neck and breast carcinoma cells by inhibiting EGFR‐related pathways of signal transduction

2002 • 240 citations

Roles of JAKs in Activation of STATs and Stimulation of c-fos Gene Expression by Epidermal Growth Factor

1996 • 221 citations

Green tea polyphenol epigallocatechin-3 gallate inhibits Her-2/neu signaling, proliferation, and transformed phenotype of breast cancer cells.

2002 • 209 citations

Green tea catechins inhibit vascular endothelial growth factor receptor phosphorylation.

2002 • 205 citations

STAT3 mediates the survival signal in oncogenicras-transfected intestinal epithelial cells

1998 • 130 citations

ErbB-2 kinase is required for constitutive stat 3 activation in malignant human lung epithelial cells

1999 • 122 citations

Chemosensitization of HER-2/neu-overexpressing human breast cancer cells to paclitaxel (Taxol) by adenovirus type 5 E1A

1997 • 96 citations

Green tea compounds inhibit tyrosine phosphorylation of PDGF β‐receptor and transformation of A172 human glioblastoma

2000 • 89 citations

Developments in chemotherapy of breast cancer

2000 • 81 citations

Induction of topoisomerase II activity after ErbB2 activation is associated with a differential response to breast cancer chemotherapy.

2001 • 77 citations

Taxanes in combined modality therapy for solid tumors

2001 • 77 citations

The Roles of JNK1 and Stat3 in the Response of Head and Neck Cancer Cell Lines to Combined Treatment with All trans‐retinoic Acid and 5‐Fluorouracil

2002 • 40 citations