Human Hepatocyte Nuclear Factor 4 Isoforms Are Encoded by Distinct and Differentially Expressed Genes

Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B.

1990 • 1,510 citations

Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily.

1990 • 1,044 citations

Luciferase reporter gene vectors for analysis of promoters and enhancers.

1988 • 1,016 citations

Disruption of the HNF-4 gene, expressed in visceral endoderm, leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos.

1994 • 550 citations

Multiple hepatocyte-enriched nuclear factors function in the regulation of transthyretin and alpha 1-antitrypsin genes.

1989 • 545 citations

A transcriptional hierarchy involved in mammalian cell-type specification

1992 • 428 citations

HNF1, a homeoprotein member of the hepatic transcription regulatory network

1992 • 210 citations

Tissue-specific expression of the gene encoding hepatocyte nuclear factor 1 may involve hepatocyte nuclear factor 4.

1991 • 192 citations

Characterization of the mouse HNF-4 gene and its expression during mouse embryogenesis

1994 • 163 citations

Retinoic acid and retinoic acid receptors in development

1995 • 138 citations

Expression of the L-type pyruvate kinase gene and the hepatocyte nuclear factor 4 transcription factor in exocrine and endocrine pancreas.

1994 • 132 citations

Dedifferentiated variants of a rat hepatoma: Reversion analysis

1980 • 129 citations

The expression pattern of a Drosophila homolog to the mouse transcription factor HNF-4 suggests a determinative role in gut formation.

1993 • 128 citations

Transcriptional control in hepatocytes: a window on development

1991 • 128 citations

Hepatocyte-specific promoter element HP1 of the Xenopus albumin gene interacts with transcriptional factors of mammalian hepatocytes

1988 • 105 citations

Tissue-Specific Regulation of Mouse Hepatocyte Nuclear Factor 4 Expression

1994 • 95 citations

Gene regulation in rodent hepatocytes during development, differentiation and disease

1993 • 85 citations

Cloning and sequencing of cDNAs encoding the human hepatocyte nuclear factor 4 indicate the presence of two isoforms in human liver

1994 • 82 citations

Mechanisms of liver-specific gene expression

1992 • 63 citations

Tissue-specific regulation of mouse hepatocyte nuclear factor 4 expression.

1994 • 57 citations

Elements and factors involved in tissue-specific and embryonic expression of the liver transcription factor LFB1 in Xenopus laevis.

1993 • 42 citations

Identification of two splice isoforms of mRNA for mouse hepatocyte nuclear factor 4 (HNF-4)

1995 • 35 citations

Lowered amounts of the tissue-specific transcription factor LFB1 (HNF1) correlate with decreased levels of glutathione S-transferase alpha messenger RNA in human renal cell carcinoma.

1994 • 34 citations

Murine chromosomal location of four hepatocyte-enriched transcription factors: HNf-3α, HNF-3β, HNF-3γ, and HNF-4

1992 • 23 citations

Estrogen‐Inducible Derivatives of Hepatocyte Nuclear Factor‐4, Hepatocyte Nuclear Factor‐3 and Liver Factor B1 are Differently Affected by Pure and Partial Antiestrogens

1994 • 17 citations

Liver specific gene expression

2002 • 9 citations