Endothelins: vasoconstrictor effects and localization in canine cerebral arteries

Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures.

1981 • 14,396 citations

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

1988 • 10,786 citations

The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes.

1989 • 2,551 citations

Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor.

1988 • 1,417 citations

Molecular biology and biochemistry of the endothelins

1989 • 620 citations

The Human Preproendothelin-1 Gene

1989 • 441 citations

Log-normal distribution of equiefective doses of norepinephrine and acetylcholine in several tissues.

1972 • 430 citations

Cellular mechanism of action by a novel vasoconstrictor endothelin in cultured rat vascular smooth muscle cells

1988 • 385 citations

Endothelin activates the dihydropyridine-sensitive, voltage-dependent Ca2+ channel in vascular smooth muscle.

1989 • 353 citations

Rat endothelin is a vasodilator in the isolated perfused mesentery of the rat

1989 • 260 citations

Endothelin and the production of cerebral vasospasm in dogs

1989 • 188 citations

Two distinct types of endothelin receptors are present on chick cardiac membranes

1989 • 176 citations

Cerebral microvessel endothelium is producing endothelin

1990 • 143 citations

Endothelin acts in feline and canine cerebral arteries from the adventitial side.

1989 • 138 citations

Endothelin and Ca++ agonist bay K 8644: Different vasoconstrictive properties

1988 • 136 citations

Endothelin localizes in the dorsal horn and acts on the spinal neurones: Possible involvement of dihydropyridine-sensitive calcium channels and substance P release

1989 • 134 citations

Effects of endothelin on the mechanical activity and cytosolic calcium levels of various types of smooth muscle

1989 • 133 citations

Endothelin-1 induces vasoconstriction through two functionally distinct pathways in porcine coronary artery: Contribution of phosphoinositide turnover

1989 • 116 citations

Vasoconstrictor response of large cerebral arteries of cats to endothelin, an endothelium-derived vasoactive peptide

1989 • 105 citations

Possible Role of Endothelial Thromboxane A2 in the Resting Tone and Contractile Responses to Acetylcholine and Arachidonic Acid in Canine Cerebral Arteries

1987 • 92 citations

Endothelial Vasoactive Substances and Cardiovascular Disease

1988 • 88 citations

Cellular mechanisms of endothelin in rabbit aorta.

1989 • 85 citations

Calcitonin gene-related peptide and vasodilator nerves in large cerebral arteries of cats.

1989 • 78 citations

Mechanism of contraction to endothelin in isolated porcine coronary artery

1989 • 71 citations

Mechanisms of relaxant action of nicardipine, a new Ca++-antagonist, on isolated dog cerebral and mesenteric arteries.

1983 • 68 citations

Endothelium‐dependent vascular activities of endothelin‐like peptides in the isolated superior mesenteric arterial bed of the rat

1990 • 59 citations

Mechanisms of contracting action of oxyhemoglobin in isolated monkey and dog cerebral arteries

1990 • 56 citations

Endothelin-1 induced contraction of rat aorta: contributions made by Ca2+ influx and activation of contractile apparatus associated with no change in cytoplasmic Ca2+ level

1990 • 48 citations

Endothelin-1 contracts isolated vessels independently of dihydropyridine-sensitive Ca2+ channel activation

1989 • 43 citations

Endothelium-dependent contractions induced by angiotensin I and angiotensin II in canine cerebral artery.

1989 • 39 citations

DILTIAZEM‐INDUCED VASODILATATION OF SMOOTH MUSCLE CELLS OF THE CANINE BASILAR ARTERY

1982 • 38 citations

Effects of Bay k 8644 and nifedipine on isolated dog cerebral, coronary and mesenteric arteries.

1987 • 26 citations

Contractile responses to calcium chloride in rat aortic rings bathed in K⁺‐free solution are resistant to organic calcium antagonists

1989 • 7 citations

Immunological and pharmacological characterizations of antiendothelin monoclonal antibody, KM565

1990 • 3 citations