The conserved exon method for gene finding.

Basic local alignment search tool

1990 • 87,358 citations

Prediction of complete gene structures in human genomic DNA

1997 • 4,041 citations

Identification of protein coding regions by database similarity search

1993 • 1,660 citations

LEDA: a platform for combinatorial and geometric computing

1995 • 996 citations

Recognition of protein coding regions in DNA sequences

1982 • 927 citations

Evaluation of Gene Structure Prediction Programs

1996 • 753 citations

A Computer Program for Aligning a cDNA Sequence with a Genomic DNA Sequence

1998 • 745 citations

Computer methods to locate signals in nucleic acid sequences

1984 • 673 citations

Evolutionary parameters of the transcribed mammalian genome: An analysis of 2,820 orthologous rodent and human sequences

1998 • 456 citations

A generalized hidden Markov model for the recognition of human genes in DNA.

1996 • 393 citations

Prediction of gene structure

1992 • 366 citations

Predicting internal exons by oligonucleotide composition and discriminant analysis of spliceable open reading frames

1994 • 348 citations

Long Human–Mouse Sequence Alignments Reveal Novel Regulatory Elements: A Reason to Sequence the Mouse Genome

1997 • 325 citations

Neural network prediction of translation initiation sites in eukaryotes: perspectives for EST and genome analysis.

1997 • 305 citations

EST_GENOME: a program to align spliced DNA sequences to unspliced genomic DNA

1997 • 277 citations

Comparative analysis of 1196 orthologous mouse and human full-length mRNA and protein sequences.

1996 • 234 citations

Comparative Analysis of Noncoding Regions of 77 Orthologous Mouse and Human Gene Pairs

1999 • 218 citations

An Assessment of Gene Prediction Accuracy in Large DNA Sequences

2000 • 217 citations

A weight array method for splicing signal analysis

1993 • 181 citations

Large-Scale Comparative Sequence Analysis of the Human and Murine Bruton’s Tyrosine Kinase Loci Reveals Conserved Regulatory Domains

1997 • 142 citations

A method for identifying splice sites and translational start sites in eukaryotic mRNA

1997 • 127 citations

Comparative sequence analysis of a gene-rich cluster at human chromosome 12p13 and its syntenic region in mouse chromosome 6.

1998 • 118 citations

Dynamite: a flexible code generating language for dynamic programming methods used in sequence comparison.

1997 • 118 citations

Comparative Sequence of Human and Mouse BAC Clones from the mnd2 Region of Chromosome 2p13

1999 • 59 citations

A High-Stakes Gamble on Genome Sequencing

1999 • 28 citations

Gene recognition via spliced alignment

2000 • 22 citations