Drug-Induced Cardiac Arrhythmias

The Cardiac Arrhythmia Suppression Trial Investigators: Preliminary Report: Effect of Encainide and Flecainide on Mortality in a Randomized Trial of Arrhythmia Suppression After Myocardial Infarction.

1990 • 1,074 citations

Efficacy and safety of quinidine therapy for maintenance of sinus rhythm after cardioversion. A meta-analysis of randomized control trials.

1990 • 960 citations

Female gender as a risk factor for torsades de pointes associated with cardiovascular drugs

1993 • 843 citations

Antiarrhythmic drug therapy and cardiac mortality in atrial fibrillation

1992 • 636 citations

Mechanism of the Cardiotoxic Actions of Terfenadine

1993 • 627 citations

Spiral waves of excitation underlie reentrant activity in isolated cardiac muscle.

1993 • 616 citations

The Electrophysiological Mechanism of Ventricular Arrhythmias in the Long QT Syndrome

1996 • 425 citations

Precordial QT interval dispersion as a marker of torsade de pointes. Disparate effects of class Ia antiarrhythmic drugs and amiodarone.

1992 • 394 citations

Short-coupled variant of torsade de pointes. A new electrocardiographic entity in the spectrum of idiopathic ventricular tachyarrhythmias.

1994 • 390 citations

Amiodarone-associated Proarrhythmic Effects: A Review with Special Reference to Torsade de Pointes Tachycardia

1994 • 380 citations

Cardiotoxicity of high-dose continuous infusion fluorouracil: a prospective clinical study.

1992 • 316 citations

Randomized antiarrhythmic drug therapy in survivors of cardiac arrest (the CASCADE study)

1993 • 283 citations

Nonstationary Vortexlike Reentrant Activity as a Mechanism of Polymorphic Ventricular Tachycardia in the Isolated Rabbit Heart

1995 • 272 citations

Electrophysiologic Mechanisms of the Long QT Interval Syndromes and Torsade de Pointes

1995 • 269 citations

Clinical Toxicity of the Interferons

1994 • 268 citations

Drugs for the Heart

1981 • 233 citations

Cardiotoxicity of Interferon*

1991 • 218 citations

Cardiac Electrophysiological Actions of the Histamine H₁-Receptor Antagonists Astemizole and Terfenadine Compared With Chlorpheniramine and Pyrilamine

1995 • 214 citations

Proarrhythmia in Patients Treated for Atrial Fibrillation or Flutter

1992 • 185 citations

5-Fluorouracil cardiotoxicity.

1990 • 158 citations

Optical Mapping of Drug-Induced Polymorphic Arrhythmias and Torsade de Pointes in the Isolated Rabbit Heart

1997 • 152 citations

Spontaneous sequences of onset of torsade de pointes in patients with acquired prolonged repolarization: Quantitative analysis of Holter recordings

1995 • 146 citations

Torsade de Pointes

1994 • 127 citations

Antiarrhythmic drugs and torsade de pointes

1993 • 122 citations

Fluorouracil Cardiotoxicity

1994 • 117 citations

Comparison of sotalol with digoxin-quinidine for conversion of acute atrial fibrillation to sinus rhythm (the sotalol-digoxin-quinidine trial)

1995 • 117 citations

Re-entrant ventricular arrhythmias in the late myocardial infarction period. 4. Mechanism of action of lidocaine.

1977 • 112 citations

OXFORD TEXTBOOK OF MEDICINE (2nd edition)

1987 • 109 citations

Frequency-dependent electrophysiologic effects of amiodarone in humans.

1993 • 109 citations

Thioridazine (Mellaril®)-induced Ventricular Tachycardia Controlled with an Artificial Pacemaker

1966 • 108 citations

Cisapride and torsades de pointes

1995 • 98 citations

Increased risk of death and cardiac arrest from encainide and flecainide in patients after non-Q-wave acute myocardial infarction in the Cardiac Arrhythmia Suppression Trial

1991 • 95 citations

Drug-Induced Torsade de Pointes

1994 • 92 citations

Early after-depolarizations and torsade de pointes: Implications for the control of cardiac arrhythmias by prolonging repolarization

1993 • 91 citations

Poisoning Due to Class IA Antiarrhythmic Drugs Quinidine, Procainamide and Disopyramide

1990 • 90 citations

Incidence of Cardiac Arrhythmias During Intravenous Pentamidine Therapy in HIV-Infected Patients

1994 • 83 citations

Isoproterenol reversal of antiarrhythmic effects in patients with inducible sustained ventricular tachyarrhythmias

1989 • 76 citations

The hazards of using type 1C antiarrhythmic drugs for the treatment of paroxysmal atrial fibrillation

1990 • 72 citations

Recurrent ventricular tachycardia associated with QT prolongation after mitral valve replacement and its association with intravenous administration of erythromycin

1984 • 71 citations

TU Alternans, Long QTU, and Torsade de Pointes: Clinical and Experimental Observations

1992 • 65 citations

Detrimental arrhythmogenic and sustained beneficial hemodynamic effects of oral salbutamol in patients with chronic congestive heart failure

1985 • 64 citations

Effect of erythromycin on ventricular arrhythmias and ventricular repolarization in idiopathic long QT syndrome

1987 • 64 citations

Incidence of adverse cardiopulmonary effects with low-dose continuous terbutaline infusion

1995 • 63 citations

Electrophysiologic profile and efficacy of intravenous dofetilide (UK-68,798), a new class III antiarrhythmic drug, in patients with sustained monomorphic ventricular tachycardia

1995 • 63 citations

Sotalol

1993 • 62 citations

Sudden death in phenothiazine therapy

1970 • 56 citations

Torsade de Pointes and T‐U Wave Alternans Associated with Arsenic Poisoning

1990 • 53 citations

Nicorandil suppresses early afterdepolarisation and ventricular arrhythmias induced by caesium chloride in rabbits in vivo

1991 • 53 citations

Assessment of the efficacy and safety of antiarrhythmic therapy for chronic atrial fibrillation: Observations on the role of trial design and implications of drug-related mortality

1992 • 49 citations

Magnesium and the heart: Antiarrhythmic therapy with magnesium

1993 • 48 citations

Cardiac Effects of Standard-Dose Halofantrine Therapy

1996 • 46 citations

Action Potential Prolongation Exhibits Simple Dose-Dependence for Sotalol, but Reverse

1993 • 46 citations

Concentration dependent cardiotoxicity of terodiline in patients treated for urinary incontinence.

1995 • 44 citations

Torsade de pointes induced by terfenadine in a patient with long QT syndrome

1994 • 42 citations

Magnesium Therapy in Ventricular Arrhythmias

1990 • 42 citations

Multiform Ventricular Tachycardia Due to the Interaction of Aminophylline and Halothane

1979 • 36 citations

Pharmacodynamic, Pharmacokinetic and Antiarrhythmic Properties of d-Sotalol, the Dextro-Isomer of Sotalol

1995 • 30 citations

Torsade de pointes complicating drug treatment of low‐malignant forms of arrhythmia: Four case reports

1994 • 29 citations

Proarrhythmic actions of antiarrhythmic drugs: a review

1990 • 28 citations

Early afterdepolarizations and arrhythmogenesis. Experimental and clinical aspects.

1991 • 28 citations

A randomized, placebo-controlled trial of propafenone in the prophylaxis of paroxysmal supraventricular tachycardia and paroxysmal atrial fibrillation. UK Propafenone PSVT Study Group.

1995 • 25 citations

Propafenone‐Induced Torsade de Pointes: Cross‐Reactivity with Quinidine

1991 • 25 citations

Mechanisms in Simulated Torsade de Pointes

1993 • 24 citations

Electrophysiologic Mechanisms for Ventricular Arrhythmias in Left Ventricular Dysfunction: Electrolytes, Catecholamines and Drugs

1991 • 24 citations

Inpatient versus outpatient initiation of antiarrhythmic drug therapy for patients with supraventricular tachycardia

2009 • 23 citations

QT interval prolongation and cardiac arrest during antibiotic therapy with spiramycin in a newborn infant

1993 • 20 citations

Case Report: Pentamidine and Polymorphic Ventricular Tachycardia Revisited

1993 • 17 citations

Cycle-length effects on the initiation of simulated torsade de pointes

1994 • 16 citations

Torsade de pointes after inhaled pentamidine

1992 • 16 citations

Congenital complete heart block and long Q-T syndrome requiring ventricular pacing for control of refractory ventricular tachycardia and fibrillation

1979 • 15 citations

[Amiodarone therapy after sotalol-induced torsade de pointes: prolonged QT interval and QT dispersion in differentiation of pro-arrhythmic effects].

1994 • 14 citations

Differential Effect of Dofetilide on Ventricular Repolarization During Steady State and During Restitution in Vivo

1994 • 13 citations

Drugs for the heart, 3rd ed

1991 • 12 citations

How reliable are clinical trials?: The importance of the criteria for early termination

1995 • 12 citations

The role of percutaneous transluminal coronary angioplasty in acute myocardial infarction.

1994 • 9 citations

["Torsades de pointe" and reentry induced by anti-arrhythmia agents].

1978 • 9 citations

N-acetylprocainamide intoxication with torsade de pointes treated by high dialysate flow rate continuous arteriovenous hemodiafiltration

1995 • 8 citations

Quinidine but Not Disopyramide Prolongs Cardiac Purkinje Fiber Action Potentials After a Pause

1994 • 8 citations

New data on the antiarrhythmic value of parenteral magnesium treatment: magnesium and ventricular arrhythmias.

1992 • 5 citations

Atrial fibrillation: Steering a management course between thromboembolism and proarrhythmic risk

1995 • 3 citations

Effective use of magnesium for acquired torsade de pointes in a 4-month-old infant

1995 • 3 citations

[Arrhythmia and anti-arrhythmia therapy as prognostic risks].

1991 • 2 citations

[Ventricular pro-arrhythmic effects of anti-arrhythmia drugs].

1992 • 1 citations

Deleted Work

1955 • 0 citations

Cited By (0)

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