APOE and Alzheimer disease: a major gene with semi-dominant inheritance

Effects of Age, Sex, and Ethnicity on the Association Between Apolipoprotein E Genotype and Alzheimer Disease

1997 • 4,137 citations

Association of apolipoprotein E allele ϵ4 with late‐onset familial and sporadic Alzheimer's disease

1993 • 3,693 citations

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

2009 • 3,258 citations

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

2009 • 2,114 citations

Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium

1997 • 1,868 citations

Meta-Analysis of BRCA1 and BRCA2 Penetrance

2007 • 1,670 citations

Genetic associations with human longevity at the APOE and ACE loci

1994 • 1,079 citations

Disclosure ofAPOEGenotype for Risk of Alzheimer's Disease

2009 • 513 citations

Apolipoprotein E Variation at the Sequence Haplotype Level: Implications for the Origin and Maintenance of a Major Human Polymorphism

2000 • 413 citations

Are sex and educational level independent predictors of dementia and Alzheimer's disease? Incidence data from the PAQUID project

1999 • 391 citations

Apolipoprotein E element 4 association with dementia in a population-based study

1996 • 346 citations

Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals

2010 • 240 citations

The lifetime risks of breast cancer in Ashkenazi Jewish carriers of BRCA1 and BRCA2 mutations.

2001 • 221 citations

Estimation of apolipoprotein E genotype-specific relative mortality risks from the distribution of genotypes in centenarians and middle-aged men: Apolipoprotein E gene is a ?frailty gene,? not a ?longevity gene?

2000 • 202 citations

Estimating risk curves for first-degree relatives of patients with Alzheimer’s disease: The REVEAL study

2004 • 163 citations

Apolipoprotein E ε4 Allele and the Lifetime Risk of Alzheimer's Disease

1995 • 161 citations

Incidence of Dementia and Alzheimer's Disease: A Reanalysis of Data from Rochester, Minnesota, 1975-1984

1998 • 158 citations

Apolipoprotein E and Alzheimer disease: genotype-specific risks by age and sex.

1997 • 136 citations

Genetic Signatures of Exceptional Longevity in Humans

2010 • 135 citations

Apolipoprotein E polymorphism and susceptibility to Alzheimer's disease.

1995 • 106 citations

Quantifying lifetime risk of psychiatric disorder

1981 • 65 citations

Using Lifetime Risk Estimates in Personal Genomic Profiles: Estimation of Uncertainty

2009 • 29 citations