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Mitogenic and anti-apoptotic activity of insulin on bovine embryos produced in vitro

Data up to Jan 2025

Published2003
Citations84
References52

Total Citations Per Year

Abstract

References (52)

Insulin signalling and the regulation of glucose and lipid metabolism

2001 • 4,995 citations

Cellular survival: a play in three Akts

1999 • 4,229 citations

Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)

1993 • 2,880 citations

Molecular thanatopsis: a discourse on the BCL2 family and cell death

1996 • 1,412 citations

Mechanisms and consequences of activation of protein kinase B/Akt

1998 • 1,305 citations

SUCCESSFUL CULTURE IN VITRO OF SHEEP AND CATTLE OVA

1972 • 1,013 citations

Nomenclature of the GLUT/SLC2A family of sugar/polyol transport facilitators

2002 • 406 citations

Hyperglycemia induces apoptosis in pre-implantation embryos through cell death effector pathways

1998 • 342 citations

Analysis of apoptosis in the preimplantation bovine embryo using TUNEL

1999 • 333 citations

Alterations in the relative abundance of gene transcripts in preimplantation bovine embryos cultured in medium supplemented with either serum or PVA

1999 • 308 citations

Insulin Rescues Retinal Neurons from Apoptosis by a Phosphatidylinositol 3-Kinase/Akt-mediated Mechanism That Reduces the Activation of Caspase-3

2001 • 288 citations

Apoptosis in the human embryo

1999 • 276 citations

Protein kinase B (PKB/Akt) – a key regulator of glucose transport?

2001 • 274 citations

Quantification of Housekeeping Transcript Levels During the Development of Bovine Preimplantation Embryos1

2002 • 206 citations

Anti-Apoptotic Action of Insulin-Like Growth Factor-I During Human Preimplantation Embryo Development

2000 • 175 citations

Maternal hyperglycemia alters glucose transport and utilization in mouse preimplantation embryos

1998 • 163 citations

Insulin and Insulin-like Growth Factor I Receptors Utilize Different G Protein Signaling Components

2001 • 161 citations

Insulin and Insulin-like Growth Factor-I Promote Rabbit Blastocyst Development and Prevent Apoptosis1

1998 • 157 citations

Specificity in ligand binding and intracellular signalling by insulin and insulin-like growth factor receptors

2001 • 157 citations

In-vitro uptake of glucose by bovine blastocysts

1980 • 152 citations

Glucose transporter gene expression: Regulation of transcription and mRNA stability

1995 • 148 citations

Glucose transporter GLUT3: Ontogeny, targeting, and role in the mouse blastocyst

1997 • 134 citations

Insulin increases the cell number of the inner cell mass and stimulates morphological development of mouse blastocysts in vitro

1990 • 133 citations

Relationship between time of first cleavage and the expression of IGF-I growth factor, its receptor, and two housekeeping genes in bovine two-cell embryos and blastocysts produced in vitro

2000 • 129 citations

Effects of streptozotocin- and alloxan-induced diabetes mellitus on mouse follicular and early embryo development

1989 • 113 citations

Apoptosis is regulated by the rate of glucose transport in an interleukin 3 dependent cell line.

1994 • 112 citations

Regulation of apoptosis in the bovine blastocyst by insulin and the insulin‐like growth factor (IGF) superfamily

2002 • 110 citations

Glucose transporters in preimplantation development

1998 • 109 citations

Expression of RNA from developmentally important genes in preimplantation bovine embryos produced in TCM supplemented with BSA

1998 • 109 citations

Signaling Pathways Mediating Insulin‐Stimulated Glucose Transport

1999 • 103 citations

Preimplantation growth factor physiology

1997 • 101 citations

Insulin, insulin-like growth factors and glucose transporters: temporal patterns of gene expression in early murine and bovine embryos

1992 • 91 citations

Glucose Transporter 8 Expression and Translocation Are Critical for Murine Blastocyst Survival1

2002 • 87 citations

Effect of diabetes mellitus on mouse pre-implantation embryo development

1991 • 87 citations

Mouse blastocysts respond metabolically to short‐term stimulation by insulin and IGF‐1 through the insulin receptor

1991 • 82 citations

Effects of antioxidants on the development of bovine IVM/IVF embryos in various concentrations of glucose

1998 • 81 citations

Bovine Oviductal and Embryonic Insulin-Like Growth Factor Binding Proteins: Possible Regulators of “Embryotrophic” Insulin-Like Growth Factor Circuits1

1997 • 78 citations

IGF-I and insulin regulate glucose transport in mouse blastocysts via IGF-I receptor

1996 • 77 citations

Mouse Preimplantation Embryos Exhibit Receptor-Mediated Binding and Transcytosis of Maternal Insulin-Like Growth Factor I1

1993 • 75 citations

Insulin Inhibits Apoptosis of Macrophage Cell Line, THP-1 Cells, via Phosphatidylinositol-3-Kinase–Dependent Pathway

2002 • 73 citations

Reproduction, fertility and developmentPapers from a Symposium on the Placenta and Fetal Membranes, 3–4 November 1990, Monash Medical Centre, Melbourne, Australia

1992 • 68 citations

Insulin and Insulin-Like Growth Factor-I(IGF-I) Stimulate the Development of Bovine Embryos Fertilized In Vitro.

1995 • 63 citations

Increased cell death in mouse blastocysts exposed to high D-glucose in vitro: implications of an oxidative stress and alterations in glucose metabolism

2002 • 51 citations

Stimulation of the development of bovine embryos by insulin and insulin-like growth factor-I (IGF-I) is mediated through the IGF-I receptor

1997 • 47 citations

One‐minute exposure of 4‐cell mouse embryos to glucose overcomes morula block in CZB medium

1994 • 42 citations

Maternal insulin treatment improves pre-implantation embryo development in diabetic rats

1992 • 42 citations

The Influence of Insulin on the in vitro Development of Mouse and Bovine Embryos

2000 • 26 citations

Differential phosphorylation of IRS-1 by insulin and insulin-like growth factor I receptors in Chinese hamster ovary cells

2001 • 25 citations

Stimulatory Effects of Insulin on the Development of Bovine Embryos Fertilized In Vitro.

1995 • 23 citations

In vitro development of ovine embryos in CZB medium

1992 • 18 citations

Growth factors in preimplantation development: role of insulin and insulin-like growth factors.

1997 • 17 citations

Influences of culture components on the development of bovine blastocysts in defined conditions

1997 • 2 citations

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Mitogenic and anti-apoptotic activity of insulin on bovine embryos produced in vitro (2003) – Reproduction | Metascience Observatory Explorer