Gastrointestinal host defense and necrotizing enterocolitis

Translocation of Certain Indigenous Bacteria from the Gastrointestinal Tract to the Mesenteric Lymph Nodes and Other Organs in a Gnotobiotic Mouse Model

1979 • 837 citations

Epithelial Cell Specialization within Human Peyer's Patches: An Ultrastructural Study of Intestinal Lymphoid Follicles

1974 • 757 citations

Sequential Uptake of Horseradish Peroxidase by Lymphoid Follicle Epithelium of Peyer's Patches in the Normal Unobstructed Mouse Intestine: An Ultrastructural Study

1977 • 673 citations

Specificity and function of T cells bearing γδ receptors

1988 • 570 citations

Uptake and transport of macromolecules by the intestine. Possible role in clinical disorders.

1974 • 483 citations

Intestinal M Cells: A Pathway for Entry of Reovirus into the Host

1981 • 481 citations

Acute Necrotizing Enterocolitis in Infancy: A Review of 64 Cases

1975 • 458 citations

The mouse gut T lymphocyte, a novel type of T cell. Nature, origin, and traffic in mice in normal and graft-versus-host conditions.

1978 • 422 citations

Proposed Mechanisms for the Translocation of Intestinal Bacteria

1988 • 412 citations

Development of the human gastrointestinal tract. A review.

1976 • 408 citations

Neonatal necrotizing enterocolitis: Pathogenesis, classification, and spectrum of illness

1987 • 387 citations

An experimental study of acute neonatal enterocolitis—the importance of breast milk

1974 • 380 citations

PROTEIN REQUIREMENTS

1974 • 375 citations

Development of the Human Gastrointestinal Tract

1976 • 373 citations

ACADEMIC STRESS, POWER MOTIVATION, AND DECREASE IN SECRETION RATE OF SALIVARY SECRETORY IMMUNOGLOBULIN A

1983 • 360 citations

Immunocompetence in undernutrition

1972 • 338 citations

Exocrine Pancreas Function in Premature and Full Term Neonates

1972 • 326 citations

Prevention of Necrotizing Enterocolitis in Low-Birth-Weight Infants by IgA–IgG Feeding

1988 • 318 citations

Uptake and Transport of Macromolecules by the Intestine

1974 • 311 citations

Protection by Milk Immunoglobulin Concentrate against Oral Challenge with EnterotoxigenicEscherichia coli

1988 • 295 citations

Defense mechanisms involving Fc-dependent functions of immunoglobulin A and their subversion by bacterial immunoglobulin A proteases

1988 • 270 citations

Intestinal Mucins in Health and Disease

1978 • 265 citations

Predictive value of Glasgow coma score for awakening after out-of-hospital cardiac arrest. Cerebral Resuscitation Study Group of the Belgian Society for Intensive Care.

1988 • 259 citations

Immunohistochemical observations on lymphoid tissues from conventional and germ-free mice.

1970 • 238 citations

Necrotizing enterocolitis in premature infants

1965 • 233 citations

Immunologic aspects of human colostrum and milk. III. Fate and absorption of cellular and soluble components in the gastrointestinal tract of the newborn.

1977 • 225 citations

Intestinal permeability in the newborn.

1984 • 216 citations

Developmental Pattern of Small Intestinal Enterokinase and Disaccharidase Activities in the Human Fetus

1977 • 213 citations

Correlation of Milk Precipitins with IgA Deficiency

1969 • 209 citations

Specific adherence of Escherichia coli (strain RDEC-1) to membranous (M) cells of the Peyer's patch in Escherichia coli diarrhea in the rabbit.

1983 • 206 citations

A Decreased Incidence of Necrotizing Enterocolitis After Prenatal Glucocorticoid Therapy

1984 • 202 citations

Responses of the Peyer's Patches in Germ-Free Mice to Antigenic Stimulation

1970 • 184 citations

Development of Gastrointestinal Mucosal Barrier. I. The Effect of Age on Intestinal Permeability to Macromolecules

1981 • 177 citations

Milk antigen absorption in the preterm and term neonate.

1982 • 174 citations

The effect of antigen deprivation on thymus-dependent and thymus-independent lymphocytes in the small intestine of the mouse.

1972 • 174 citations

Gastrointestinal Cell Plasma Membrane Wounding and Resealing In Vivo

1989 • 168 citations

EARLY STAGES OF INTESTINAL ABSORPTION OF SPECIFIC ANTIBODIES IN THE NEWBORN

1969 • 162 citations

Protection against Experimental Necrotizing Enterocolitis by Maternal Milk. I. Role of Milk Leukocytes

1977 • 156 citations

Summer outbreak of influenza type-B.

1962 • 150 citations

Isolation and Propagation of a Human Enteric Coronavirus

1985 • 146 citations

Pathogenesis of neonatal Escherichia coli meningitis: induction of bacteremia and meningitis in infant rats fed E. coli K1

1977 • 143 citations

Time of Appearance of Immunoglobulin-Containing Cells in the Mucosa of the Neonatal Intestine

1980 • 141 citations

PATHOGENESIS OF NEONATAL NECROTISING ENTEROCOLITIS

1982 • 135 citations

Defense mechanisms involving Fc-dependent functions of immunoglobulin A and their subversion by bacterial immunoglobulin A proteases.

1988 • 134 citations

Immunologic Aspects of Human Colostrum and Milk

1977 • 133 citations

Microbial flora of the mouse ileum mucous layer and epithelial surface

1982 • 131 citations

The anatomical basis for the immune function of the gut

1987 • 131 citations

Treatment of infantile E. coli gastroenteritis with specific bovine anti-E. coli milk immunoglobulins

1979 • 129 citations

Ontogeny of Secretory Immunity: Levels of Secretory IgA and Natural Antibodies in Saliva

1980 • 128 citations

PIG-BEL: ENTERITIS NECROTICANS

1966 • 124 citations

Gastrointestinal permeability changes in the preterm neonate.

1982 • 116 citations

Inhibition of Escherichia coli Translocation from the Gastrointestinal Tract by Normal Cecal Flora in Gnotobiotic or Antibiotic-Decontaminated Mice

1980 • 114 citations

Secretory and Serum IgA in Children with Protein-Calorie Malnutrition

1974 • 112 citations

Thermal Injury Promotes Bacterial Translocation From the Gastrointestinal Tract in Mice With Impaired T-Cell—Mediated Immunity

1986 • 112 citations

Absence of secretory component expression by epithelial cells overlying rabbit gut-associated lymphoid tissue

1988 • 111 citations

Effect of Starvation, Malnutrition, and Trauma on the Gastrointestinal Tract Flora and Bacterial Translocation

1987 • 109 citations

Induction of bacteremia in newborn rats by Escherichia coli K1 is correlated with only certain O (lipopolysaccharide) antigen types

1983 • 105 citations

Salivary immunoglobulinand albumin: Development during the newborn period

1968 • 104 citations

Pathogenesis and Prevention of Necrotizing Enterocolitis: A Hypothesis Based on Personal Observation and a Review of the Literature

1984 • 102 citations

Secretory and Serum IgA in Children With Protein-Calorie Malnutrition

1975 • 98 citations

Increase in human intestinal permeability following ingestion of hypertonic solutions.

1977 • 97 citations

Effect of Hyperosmolar Stimuli and Coeliac Disease on the Permeability of the Human Gastrointestinal Tract

1978 • 94 citations

Complete Covalent Structure of a Human IgA1 Immunoglobulin

1976 • 93 citations

Food Allergy and Intolerance

1987 • 93 citations

A prospective controlled trial of oral kanamycin in the prevention of neonatal necrotizing enterocolitis

1976 • 90 citations

Milk Feeding and Changes in Intestinal Permeability and Morphology in the Newborn

1987 • 90 citations

Survival of Oral Human Immune Serum Globulin in the Gastrointestinal Tract of Low Birth Weight Infants

1981 • 89 citations

Development of Gastrointestinal Mucosal Barrier. II. The Effect of Natural Versus Artificial Feeding on Intestinal Permeability to Macromolecules

1981 • 88 citations

Bacterial and viral coproantibodies in breast-fed infants.

1967 • 88 citations

Immune Globulin Levels in Colostrum and Breast Milk, and Serum From Fomula- and Breast-Fed Newborns.

1966 • 85 citations

Quantitative determination of macromolecular transport rate across intestinal Peyer's patches

1983 • 83 citations

Intestinal Uptake of Macromolecules. VI. Uptake of Protein Antigen In Vivo in Normal Rats and in Rats Infected with Nippostrongylus brasifiensis or Subjected to Mild Systemic Anaphylaxis

1979 • 82 citations

Perinatal risk factors for necrotizing enterocolitis.

1984 • 82 citations

Significance of the goblet-cell mucin layer, the outermost luminal barrier to passage through the gut wall

1980 • 81 citations

PREVENTION OF NECROTISING ENTERITIS IN PAPUA NEW GUINEA BY ACTIVE IMMUNISATION

1979 • 81 citations

BACTERIAL AND VIRAL COPROANTIBODIES IN BREAST-FED INFANTS

1967 • 80 citations

An Outbreak of Clostridium difficile Necrotizing Enterocolitis: A Case for Oral Vancomycin Therapy?

1983 • 80 citations

Development of the gastrointestinal mucosal barrier. Evidence for structural differences in microvillus membranes from newborn and adult rabbits

1983 • 79 citations

The Structure and Function of Gastrointestinal Mucus

2018 • 76 citations

Ganciclovir for Cytomegalo-virus Infection in Renal-transplant Recipients

1989 • 72 citations

The Pathogenesis of Shigella Diarrhea. II. Enterotoxin-induced Acute Enteritis in the Rabbit Ileum

1972 • 71 citations

Oral Gentamicin Therapy in the Prevention of Neonatal Necrotizing Enterocolitis

1978 • 69 citations

Intestinal membrane lipid composition and fluidity during development in the rat

1985 • 66 citations

Human Milk and Breast Feeding: an Update on the State of the Art

1982 • 65 citations

How contagious is necrotizing enterocolitis?

1983 • 59 citations

IS MUCUS A SELECTIVE BARRIER TO MACROMOLECULES?

1978 • 59 citations

Alterations in stool flora resulting from oral kanamycin prophylaxis of necrotizing enterocolitis

1978 • 58 citations

Intestinal Absorption of Immunoglobulins by Newborn Infants

1972 • 57 citations

IV—The effect of pancreatic duct ligation on the breakdown of antigen and antigen-antibody complexes on the intestinal surface

1975 • 57 citations

Binding of Cholera Toxin to Mucins and Inhibition by Gastric Mucin

1974 • 57 citations

The Physiologic and Pathologic Basis for the Transport of Macromolecules Across the Intestinal Tract

1982 • 54 citations

Age at Onset of Necrotizing Enterocolitis

1982 • 50 citations

Development of the capacity to produce specific antibody to an ingested food antigen in the premature infant

1975 • 48 citations

TRANSPORT OF PROTEASES ACROSS NEONATAL INTESTINE AND DEVELOPMENT OF LIVER DISEASE IN INFANTS WITH α1-ANTITRYPSIN DEFICIENCY

1982 • 41 citations

Intestinal Permeability to Large Particles in Normal and Protein-Deficient Adult Rats

1976 • 41 citations

A case control study of necrotizing enterocolitis occurring over 8 years in a neonatal intensive care unit

1987 • 41 citations

Small intestinal permeability. 1. Effects of ischaemia and exposure to acetyl salicylate.

1976 • 40 citations

Prenatal induction of sucrase activity in rat jejunum

1977 • 39 citations

The effect of staphylococcal enterotoxin on the epithelial mucosubstances of the small intestine of rhesus monkeys.

1970 • 39 citations

Enterotoxigenic Intestinal Bacteria in Tropical Sprue

1975 • 38 citations

A model for the study of the oral administration of peptide hormones

1979 • 37 citations

Intestinal Lesions Containing Coronavirus-like Particles in Neonatal Necrotizing Enterocolitis: An Ultrastructural Analysis

1984 • 37 citations

Development of the Gastrointestinal Mucosal Barrier

1984 • 36 citations

Timing of the Gut Closure

1984 • 36 citations

Short Communication. Age at Onset of Necrotizing Enterocolitis

1982 • 34 citations

Glucocorticoid-Mediated Alteration of Fluidity of Brush Border Membrane in Rat Small Intestine

1986 • 30 citations

Development of the Gastrointestinal Mucosal Barrier: Changes in Phospholipid Head Groups and Fatty Add Composition of Intestinal Microvillus Membranes from Newborn and Adult Rats

1988 • 29 citations

Gastric acid output and circulating antibovine serum albumin in adults.

1967 • 26 citations

Cholera Toxin-Induced Glycoprotein Secretion in Rabbit Small Intestine

1979 • 24 citations

Feeding the Premature and Compromised Infant: Gastrointestinal Considerations

1988 • 21 citations

Proteolytic Activity as a Regulator of the Transmission of Orally Fed Proteins from the Gut to the Blood Serum in the Suckling Rat

1982 • 19 citations

Concentrations of Trimethoprim-Sulfamethoxazole in Blood After a Single, Large Oral Dose

1976 • 19 citations

The Role of Host Factors in an Outbreak of Necrotizing Enterocolitis

1984 • 19 citations

Intestinal Absorption of IgA in the Newborn

1983 • 18 citations

Oral vancomycin in prevention of necrotising enterocolitis.

1988 • 17 citations

Relationship of Birth Weight to the Pathogenesis of Necrotizing Enterocolitis in the Neonatal Piglet

1988 • 17 citations

Twins and Triplets With Necrotizing Enterocolitis

1988 • 12 citations

Allergy to Cow Milk-1985

1986 • 12 citations

Effects of the Normal Flora on Host Defenses Against Microbial Invasion

1969 • 11 citations

Maturation of intestinal host defense: An update

1981 • 9 citations

Twins and Triplets With Necrotizing Enterocolitis

1989 • 8 citations

Necrotizing Enterocolitis after the Neonatal Period

1987 • 3 citations