Abnormal constitutional karyotypes in patients with neuroblastoma: a report of four new cases and review of 47 others in the literature

A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

1986 • 2,968 citations

Amplification of N- myc in Untreated Human Neuroblastomas Correlates with Advanced Disease Stage

1984 • 2,248 citations

Smith's Recognizable Patterns of Human Malformation

1998 • 1,959 citations

Smith's recognizable patterns of human malformation

1997 • 1,917 citations

Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour

1983 • 1,407 citations

The DNA sequence of human chromosome 21

2000 • 1,406 citations

Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping

1990 • 1,300 citations

Risks of leukaemia and solid tumours in individuals with Down's syndrome

2000 • 847 citations

Targeted expression of MYCN causes neuroblastoma in transgenic mice

1997 • 830 citations

Chromosomal Imbalance in the Aniridia-Wilms' Tumor Association: 11p Interstitial Deletion

1978 • 726 citations

Functional roles of S100 proteins, calcium-binding proteins of the EF-hand type

1999 • 674 citations

Gain of Chromosome Arm 17q and Adverse Outcome in Patients with Neuroblastoma

1999 • 543 citations

Retinoblastoma and Subband Deletion of Chromosome 13

1978 • 455 citations

Allelic Loss of Chromosome 1p as a Predictor of Unfavorable Outcome in Patients with Neuroblastoma

1996 • 435 citations

Aniridia-Wilms’ tumor association: evidence for specific deletion of 11p13

1979 • 404 citations

Chromosomal aberrations in human neuroblastomas

1977 • 329 citations

Advances in neuroblastoma research

1980 • 325 citations

Pattern of malignant disorders in individuals with Down's syndrome

2001 • 286 citations

Neurite extension and neuronal survival activities of recombinant S100 beta proteins that differ in the content and position of cysteine residues.

1989 • 269 citations

Chromosome 1p36 Deletions: The Clinical Phenotype and Molecular Characterization of a Common Newly Delineated Syndrome

1997 • 269 citations

Human neuroblastomas and abnormalities of chromosomes 1 and 17.

1984 • 251 citations

Allelic deletion at 11q23 is common in MYCN single copy neuroblastomas

1999 • 250 citations

Cancer incidence in men with Klinefelter syndrome

1995 • 243 citations

Clinical Pediatric Oncology

1974 • 220 citations

Progress in Cancer Research and Therapy.

1978 • 195 citations

Genetic Disorders and the Fetus: Diagnosis, Prevention, and Treatment

2015 • 190 citations

Gain of chromosome 17 is the most frequent abnormality detected in neuroblastoma by comparative genomic hybridization.

1997 • 185 citations

Molecular biology and genetics of human neuroblastoma

1989 • 184 citations

A tumor profile in Down syndrome

1998 • 178 citations

Allelic loss of chromosome 1 and additional chromosome 17 material are both unfavourable prognostic markers in neuroblastoma

1995 • 174 citations

Abnormalities of chromosome 1p in human neuroblastoma tumors and cell lines

1982 • 169 citations

High serum endostatin levels in Down syndrome: implications for improved treatment and prevention of solid tumours

2001 • 149 citations

Neuroblastoma tumour genetics: clinical and biological aspects

2001 • 127 citations

Comparative genomic hybridization (CGH) analysis of stage 4 neuroblastoma reveals high frequency of 11q deletion in tumors lackingMYCN amplification

2001 • 124 citations

Childhood Cancer and Congenital Defects A Study of U.S. Death Certificates During the Period 1960–1966

1969 • 120 citations

Constitutional 1p36 deletion in a child with neuroblastoma.

1993 • 113 citations

Anti-Hu antibody in a neuroblastoma-associated paraneoplastic syndrome

1994 • 111 citations

Constitutional translocation t(1;17)(p36;q12–21) in a patient with neuroblastoma

1990 • 106 citations

Genetic Disorders and the Fetus: Diagnosis, Prevention, and Treatment

1999 • 100 citations

A lack of neuroblastoma in Down syndrome: a study from 11 European countries.

1998 • 96 citations

Multicentre analysis of patterns of DNA gains and losses in 204 neuroblastoma tumors: How many genetic subgroups are there?

2001 • 90 citations

Neuroblastoma: Epidemiologic Approach to Its Origin

1968 • 89 citations

Prenatal diagnosis of chromosomal abnormalities through amniocentesis

1992 • 84 citations

The N-myc and c-myc downstream pathways include the chromosome 17q genes nm23-H1 and nm23-H2

2002 • 78 citations

Nongonadal neoplasia in Turners syndrome

1970 • 73 citations

NB4S, a Member of the TBC1 Domain Family of Genes, is Truncated as a Result of a Constitutional t(1;10)(p22;q21) Chromosome Translocation in a Patient with Stage 4S Neuroblastoma

1998 • 71 citations

Trisomy 2p: Analysis of unusual phenotypic findings

1995 • 70 citations

Disruption of genes in the retinoid cascade may explain the microscopic neuroblastoma in a fetus with de novo unbalanced translocation (3;10)(q21;q26)

1995 • 68 citations

Clinical Pediatric Oncology

1992 • 65 citations

Causes of death in X chromatin positive males (Klinefelter's syndrome).

1985 • 61 citations

Agenesis of the lung associated with a chromosome abnormality (46,XX,2p+).

1980 • 58 citations

Chromosomal locations and modes of action of genes of the retinoid (vitamin A) system support their involvement in the etiology of schizophrenia

1995 • 52 citations

The p16 (CDKN2A) gene is involved in the growth of neuroblastoma cells and its expression is associated with prognosis of neuroblastoma patients

1998 • 44 citations

Neuroblastoma and related tumors in Turner’s syndrome

1997 • 44 citations

Autosomal dominant congenital cataract and microphthalmia associated with a familial t(2;16) translocation

1992 • 44 citations

Homozygous deletion of the neurofibromatosis-1 gene in the tumor of a patient with neuroblastoma

1997 • 39 citations

Simultaneous adrenocortical carcinoma and ganglioneuroblastoma in a child with Turner syndrome and germline p53 mutation.

1998 • 37 citations

Molecular analysis of the region of distal 1p commonly deleted in Neuroblastoma

1997 • 36 citations

Familial neuroblastoma

1975 • 35 citations

A case of partial 2p trisomy with neuroblastoma

1980 • 32 citations

Les cancers mammaires des femmes trisomiques 21

2001 • 31 citations

Neuroblastoma in a boy with MCA/MR syndrome, deletion 11q, and duplication 12q

1995 • 30 citations

Localization of a hereditary neuroblastoma predisposition gene to 16p12-p13

2000 • 28 citations

Germline duplication of chromosome 2p and neuroblastoma.

1997 • 25 citations

Trisomy 18 and neurogenic neoplasia

1981 • 24 citations

FAMILIAL NEUROBLASTOMA AND TRISOMY 13

1971 • 23 citations

Molecular characterization of the 1p22 breakpoint region spanning the constitutional translocation breakpoint in a neuroblastoma patient with a t(1;10)(p22;q21)

1998 • 22 citations

8p trisomy in a malformed foetus.

1982 • 22 citations

Two cases of trisomy D associated with adrenal tumours.

1972 • 21 citations

Chromosome 2 short arm translocations revealed by M-FISH analysis of neuroblastoma cell lines

2000 • 20 citations

Excess of congenital abnormalities in French-Canadian children with neuroblastoma: A case series study from Montreal

1997 • 19 citations

Inherited partial trisomy #15 complicated by neuroblastoma

1984 • 19 citations

Cytogenetic investigations of solid tumours of children.

1988 • 19 citations

Patterns of oncogene activation in human neuroblastoma cells.

1997 • 19 citations

Genetics of familial neuroblastoma: Long-range studies

1982 • 19 citations

Neuroblastoma in monozygotic twins – a case of probable twin-to-twin metastasis

2001 • 19 citations

Molecular characterization of a (1;10)(p22;q21) constitutional translocation from a patient with neuroblastoma

1995 • 17 citations

Cytogenetic observations in children with neuroblastoma.

1971 • 16 citations

CYTOGENETIC OBSERVATIONS IN CHILDREN WITH NEUROBLASTOMA

1971 • 16 citations

Isolation of chromosome-specific DNA sequences from an Alu polymerase chain reaction library to define the breakpoint in a patient with a constitutional translocation t(1;13) (q22;q12) and ganglioneuroblastoma.

1992 • 16 citations

Genetics of Wilms Tumor

1995 • 16 citations

46,XY/47,XY,+ 17p+ mosaicism in amniocytes associated with fetal abnormalities despite normal fetal blood karyotype

1993 • 15 citations

A decreased incidence of neuroblastomas in Down's syndrome and overproduction of S-100 b protein

1996 • 14 citations

Characterisation of the chromosome breakpoints in a patient with a constitutional translocation t(1;17)(p36.31-p36.13;q11.2-q12) and neuroblastoma

1995 • 14 citations

Short communication: Identical chromosome 1p breakpoint abnormality in both the tumor and the constitutional karyotype of a patient with neuroblastoma

1988 • 13 citations

Neuroblastoma in a dysmorphic girl with a partial duplication of 2p caused by an unbalanced translocation

2002 • 12 citations

Analysis of loss of heterozygosity at 16p12-p13 (familial neuroblastoma locus) in 470 neuroblastomas including both sporadic and mass screening tumors

2000 • 11 citations

Microscopic neuroblastoma in a fetus with a de novo unbalanced translocation 3;10

1994 • 11 citations

Chromosomes in familial neuroblastoma

1981 • 9 citations

Abnormal Number of X Chromosomes and Neuroblastic Tumors

2001 • 7 citations

Neuroblastoma with opsomyoclonus and turner syndrome

1984 • 7 citations

Acute plasmacytic interstitial nephritis in a child with Down syndrome

1999 • 6 citations

A case of mosaic Down's syndrome concomitant with ganglioneuroma

1989 • 6 citations

Ganglioneuroma of left adrenal gland in a patient with Turner syndrome during growth hormone therapy

1997 • 6 citations

Turner's syndrome with sympathoblastoma.

1983 • 3 citations

A case of Down's syndrome associated with progressive extradural neuroblastoma

1999 • 2 citations

Neuroblastoma and partial 15q duplication in the fetus.

1994 • 2 citations

Trisomy 18 syndrome

1997 • 2 citations

Étude cytogénétique moléculaire du neuroblastome de l'enfant par hybridation génomique comparative

1999 • 1 citations

Neuroblastoma in Down syndrome

1999 • 1 citations

Deleted Work

1955 • 0 citations