Recombinant Antibodies in Bioactive Peptide Design

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

Sequences of proteins of immunological interest

1984 • 3,427 citations

Assembly of combinatorial antibody libraries on phage surfaces: the gene III site.

1991 • 1,178 citations

Binding activities of a repertoire of single immunoglobulin variable domains secreted from Escherichia coli

1989 • 989 citations

Generation of a Large Combinatorial Library of the Immunoglobulin Repertoire in Phage Lambda

1989 • 810 citations

Using known substructures in protein model building and crystallography.

1986 • 766 citations

Expression cloning of a receptor for human granulocyte-macrophage colony-stimulating factor.

1989 • 711 citations

A large array of human monoclonal antibodies to type 1 human immunodeficiency virus from combinatorial libraries of asymptomatic seropositive individuals.

1991 • 662 citations

Molecular cloning of a second subunit of the receptor for human granulocyte-macrophage colony-stimulating factor (GM-CSF): reconstitution of a high-affinity GM-CSF receptor.

1990 • 650 citations

YIGSR, a Synthetic Laminin Pentapeptide, Inhibits Experimental Metastasis Formation

1987 • 555 citations

A point mutation in the neu oncogene mimics ligand induction of receptor aggregation

1989 • 432 citations

A pentapeptide from the laminin B1 chain mediates cell adhesion and binds to 67000 laminin receptor

1987 • 431 citations

Semisynthetic combinatorial antibody libraries: a chemical solution to the diversity problem.

1992 • 373 citations

Critical cytoplasmic domains of the common beta subunit of the human GM-CSF, IL-3 and IL-5 receptors for growth signal transduction and tyrosine phosphorylation.

1992 • 365 citations

Structure of a λ-type Bence-Jones protein at 3.5-Å resolution

1973 • 356 citations

Novel anti-inflammatory peptides from the region of highest similarity between uteroglobin and lipocortin I

1988 • 244 citations

A monoclonal antibody against the platelet fibrinogen receptor contains a sequence that mimics a receptor recognition domain in fibrinogen

1989 • 213 citations

Rearrangement of genetic information may produce immunoglobulin diversity

1978 • 209 citations

Novel Fold and Putative Receptor Binding Site of Granulocyte-Macrophage Colony-Stimulating Factor

1991 • 206 citations

Characterization of the human granulocyte-macrophage colony-stimulating factor receptor.

1988 • 202 citations

Human monoclonal Fab fragments derived from a combinatorial library bind to respiratory syncytial virus F glycoprotein and neutralize infectivity.

1992 • 181 citations

Nucleic acid sequence of an internal image-bearing monoclonal anti-idiotype and its comparison to the sequence of the external antigen.

1986 • 161 citations

Characterization of the cell surface receptor for granulocyte-macrophage colony-stimulating factor.

1986 • 149 citations

Identification of a second active site in laminin for promotion of cell adhesion and migration and inhibition of in vivo melanoma lung colonization

1989 • 127 citations

Residue 21 of human granulocyte-macrophage colony-stimulating factor is critical for biological activity and for high but not low affinity binding.

1992 • 112 citations

Design of bioactive peptides based on antibody hypervariable region structures. Development of conformationally constrained and dimeric peptides with enhanced affinity.

1991 • 110 citations

The amino-terminal helix of GM-CSF and IL-5 governs high affinity binding to their receptors.

1991 • 103 citations

Regulation of surface expression of the granulocyte/macrophage colony-stimulating factor receptor in normal human myeloid cells.

1990 • 99 citations

Development of biologically active peptides based on antibody structure.

1989 • 90 citations

Hematopoietic activity of granulocyte/macrophage colony-stimulating factor is dependent upon two distinct regions of the molecule: functional analysis based upon the activities of interspecies hybrid growth factors.

1989 • 89 citations

Linkage of tyrosine kinase activity with transforming ability of the p185neu oncoprotein.

1989 • 89 citations

Sequences of the cell-attachment sites of reovirus type 3 and its anti-idiotypic/antireceptor antibody: modeling of their three-dimensional structures.

1988 • 86 citations

Vertical transmission of human immunodeficiency virus (HIV) infection. Reactivity of maternal sera with glycoprotein 120 and 41 peptides from HIV type 1.

1992 • 84 citations

A complementarity-determining region synthetic peptide acts as a miniantibody and neutralizes human immunodeficiency virus type 1 in vitro.

1993 • 82 citations

Characterization and molecular features of the cell surface receptor for human granulocyte-macrophage colony-stimulating factor.

1990 • 74 citations

Structure-function studies of human granulocyte-macrophage colony-stimulating factor. Identification of residues required for activity.

1988 • 66 citations

Molecular mimicry of hepatitis B surface antigen by an anti-idiotype-derived synthetic peptide.

1992 • 62 citations

Characterization of granulocyte-macrophage colony-stimulating factor receptor on the blast cells of acute myeloblastic leukemia

1990 • 51 citations

Identification of critical regions in mouse granulocyte-macrophage colony-stimulating factor by scanning-deletion analysis.

1989 • 50 citations

High affinity ligand binding is not essential for granulocyte-macrophage colony-stimulating factor receptor activation.

1992 • 49 citations

Two neutralizing monoclonal antibodies against human granulocyte-macrophage colony-stimulating factor recognize the receptor binding domain of the molecule.

1990 • 49 citations

RGD-containing peptides inhibit the synthesis of myelin-like membrane by cultured oligodendrocytes.

1988 • 47 citations

Construction of a Recombinant Bacterial Human CD4 Expression System Producing a Bioactive CD4 Molecule

1992 • 45 citations

Identification of functionally distinct domains of human granulocyte- macrophage colony-stimulating factor using monoclonal antibodies

1991 • 43 citations

Contact residues and predicted structure of the reovirus type 3-receptor interaction

1991 • 39 citations

Peptide sequences from the hypervariable regions of two monoclonal anti-idiotypic antibodies against the thyrotropin (TSH) receptor are similar to TSH and inhibit TSH-increased cAMP production in FRTL-5 thyroid cells.

1992 • 38 citations

Single proline substitutions in predicted alpha-helices of murine granulocyte-macrophage colony-stimulating factor result in a loss in bioactivity and altered glycosylation.

1991 • 30 citations

Mutagenesis of murine granulocyte/macrophage-colony-stimulating factor reveals critical residues near the N terminus

1987 • 29 citations

Molecular cloning of a soluble form of the granulocyte‐‐macrophage colony‐stimulating factor receptor α chain from a myelomonocytic cell line. expression, biologic activity, and preliminary analysis of transcript distribution

1994 • 24 citations

Effects of polyunsaturated fatty acids on interleukin-2-dependent T cell growth

1992 • 24 citations

Human Granulocyte-Macrophage Colony-Stimulating Factor (hGM-CSF): Identification of a Binding Site for a Neutralizing Antibody

1990 • 20 citations

Molecular structure of a cross-reactive idiotype on autoantibodies recognizing parenchymal self.

1993 • 20 citations

Double-stranded DNA sequencing by linear amplification with Taq DNA polymerase.

1992 • 16 citations

Isolated VH4 Heavy Chain Variable Regions Bind DNA Characterization of a Recombinant Antibody Heavy Chain Library Derived from Patient(s) with Active SLE

1994 • 13 citations

Molecular characterization and structural modeling of immunoglobulin variable regions from murine monoclonal antibodies specific for hepatitis B virus surface antigen

1993 • 10 citations

Subtype‐Selective Immunoprecipitation of the β₂‐Adrenergic Receptor

1989 • 8 citations

Identification of functional domains in murine granulocyte-macrophage colony-stimulating factor using monoclonal antibodies to synthetic peptides.

1993 • 7 citations