Reduced Striatal Dopamine Transporter Density in Abstinent Methamphetamine and Methcathinone Users: Evidence from Positron Emission Tomography Studies with [¹¹C]WIN-35,428

Uneven Pattern of Dopamine Loss in the Striatum of Patients with Idiopathic Parkinson's Disease

1988 • 1,881 citations

Dopamine (3-hydroxytyramine) and brain function.

1966 • 1,401 citations

Striatal dopamine nerve terminal markers in human, chronic methamphetamine users

1996 • 715 citations

Long-lasting depletions of striatal dopamine and loss of dopamine uptake sites following repeated administration of methamphetamine

1980 • 533 citations

Role for Excitatory Amino Acids in Methamphetamine-Induced Nigrostriatal Dopaminergic Toxicity

1989 • 495 citations

Dopamine nerve terminal degeneration produced by high doses of methylamphetamine in the rat brain

1982 • 480 citations

Long-term effects of multiple doses of methamphetamine on tryptophan hydroxylase and tyrosine hydroxylase activity in rat brain.

1980 • 444 citations

Positron emission tomographic imaging of the dopamine transporter with ¹¹C‐WIN 35,428 reveals marked declines in mild Parkinson's disease

1993 • 319 citations

Presynaptic monoaminergic vesicles in Parkinson's disease and normal aging

1996 • 312 citations

Long-term methamphetamine induced changes in brain catecholamines in tolerant rhesus monkeys

1976 • 307 citations

MRI-PET Correlation in Three Dimensions Using a Volume-of-Interest (VOI) Atlas

1991 • 267 citations

Cocaine receptors labeled by [3H]2 beta-carbomethoxy-3 beta-(4-fluorophenyl)tropane.

1989 • 248 citations

Severe depletion of cocaine recognition sites associated with the dopamine transporter in Parkinson's‐diseased striatum

1991 • 237 citations

Age-related decline in striatal dopamine transporter binding with iodine-123-beta-CITSPECT.

1995 • 227 citations

Further evidence that amphetamines produce long-lasting dopamine neurochemical deficits by destroying dopamine nerve fibers

1984 • 216 citations

Differential changes in neurochemical markers of striatal dopamine nerve terminals in idiopathic Parkinson's disease

1996 • 214 citations

Brain Dopamine Neurotoxicity in Baboons Treated with Doses of Methamphetamine Comparable to Those Recreationally Abused by Humans: Evidence from [¹¹C]WIN-35,428 Positron Emission Tomography Studies and DirectIn VitroDeterminations

1998 • 212 citations

Long-term effects of chronic methamphetamine administration in rhesus monkeys

1989 • 209 citations

Decreased dopamine transporters with age in healthy human subjects

1994 • 205 citations

In vivo imaging of baboon and human dopamine transporters by positron emission tomography using [¹¹C]WIN 35,428

1993 • 178 citations

Treatment of mice with methamphetamine produces cell loss in the substantia nigra

1996 • 160 citations

Elevated Striatal Dopamine Transporters During Acute Cocaine Abstinence as Measured by [¹²³I]β-CIT SPECT

1998 • 149 citations

Amphetamine induces depletion of dopamine and loss of dopamine uptake sites in caudate

1980 • 139 citations

p53‐Knockout Mice Are Protected Against the Long‐Term Effects of Methamphetamine on Dopaminergic Terminals and Cell Bodies

1997 • 119 citations

Methamphetamine-induced changes in brain catecholamines in rats and guinea pigs

1979 • 118 citations

Alpha-methyltyrosine attenuates and reserpine increases methamphetamine-induced neuronal changes

1983 • 106 citations

Reduced striatal vesicular monoamine transporters after neurotoxic but not after behaviorally-sensitizing doses of methamphetamine

1997 • 105 citations

Extrapolation of Toxicological and Pharmacological Data from Animals to Humans

1991 • 104 citations

Long-term effects of continuous exposure to amphetamine on brain dopamine concentration and synaptosomal uptake in mice

1980 • 97 citations

Long-term effects of methamphetamine on the synthesis and metabolism of 5-hydroxytryptamine in various regions of the rat brain

1981 • 96 citations

Reduction in dopamine transporter mRNA after cessation of repeated cocaine administration

1994 • 94 citations

Autoradiographic localization of cocaine binding sites by [³H]CFT ([³H]WIN 35,428) in the monkey brain

1990 • 90 citations

Monoamine re-uptake sites in the human brain evaluatedin vivoby means of¹¹C-nomifensine and positron emission tomography: the effects of age and Parkinson's disease

1988 • 88 citations

Differential regulation of dopamine transporter after chronic self-administration of bupropion and nomifensine.

1997 • 73 citations

Methcathinone: A russian designer amphetamine infiltrates the rural midwest

1993 • 72 citations

Increased basic fibroblast growth factor mRNA following contusive spinal cord injury

1994 • 66 citations

Chronic cocaine administration is associated with behavioral sensitization and time-dependent changes in striatal dopamine transporter binding.

1994 • 64 citations

Neurotoxic and pharmacologic studies on enantiomers of the N-methylated analog of cathinone (methcathinone): a new drug of abuse.

1996 • 63 citations

Distribution of cocaine recognition sites in monkey brain: I. In vitro autoradiography with [³H]CFT

1991 • 61 citations

Decreased striatal monoaminergic terminals in olivopontocerebellar atrophy and multiple system atrophy demonstrated with positron emission tomography

1996 • 56 citations

Synthesis of a radiotracer for studying dopamine uptake sites in vivo using PET: 2β‐carbomethoxy‐3β‐(4‐fluorophenyl)‐[N‐¹¹C‐methyl]tropane ([¹¹C]CFT or [¹¹C]WIN‐35,428)

1993 • 51 citations

Striatal dihydroxyphenylalanine decarboxylase and tyrosine hydroxylase protein in idiopathic Parkinson's disease and dominantly inherited olivopontocerebellar atrophy

1995 • 43 citations

Methcathinone: an initial study of its effects on monoaminergic systems.

1996 • 39 citations

Long-term decreases in spontaneous firing of caudate neurons induced by amphetamine in cats

1980 • 31 citations

Methcathinone: The Next Illicit Stimulant Epidemic?

1995 • 14 citations