UTILITY OF ADENOVIRAL-MEDIATED FAS LIGAND GENE TRANSFER TO MODULATE ISLET ALLOGRAFT SURVIVAL1

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

1992 • 2,932 citations

Fas Ligand-Induced Apoptosis as a Mechanism of Immune Privilege

1995 • 2,028 citations

Lethal effect of the anti-Fas antibody in mice

1993 • 1,915 citations

A role for CD95 ligand in preventing graft rejection

1995 • 1,184 citations

Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures

1989 • 1,159 citations

Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis

1996 • 980 citations

Fas and Fas ligand: lpr and gld mutations

1995 • 906 citations

Immune responses to transgene–encoded proteins limit the stability of gene expression after injection of replication–defective adenovirus vectors

1996 • 640 citations

The JAM test A simple assay for DNA fragmentation and cell death

1991 • 632 citations

Potential Involvement of Fas and Its Ligand in the Pathogenesis of Hashimoto's Thyroiditis

1997 • 584 citations

Adenovirus-mediated transfer of low density lipoprotein receptor gene acutely accelerates cholesterol clearance in normal mice.

1993 • 531 citations

Prevention of Islet Allograft Rejection with Engineered Myoblasts Expressing FasL in Mice

1996 • 456 citations

Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets them for rapid destruction

1997 • 453 citations

CD95-Induced Apoptosis of Lymphocytes in an Immune Privileged Site Induces Immunological Tolerance

1996 • 394 citations

Transgenic expression of CD95 ligand on islet β cells induces a granulocytic infiltration but does not confer immune privilege upon islet allografts

1997 • 373 citations

Perifusion of Isolated Rat Islets in Vitro: Participation of the Microtubular System in the Biphasic Release of Insulin

1972 • 311 citations

Studies on the induction of anterior chamber‐associated immune deviation (ACAID) III. Induction of ACAID depends upon intraocular transforming growth factor‐β

1992 • 250 citations

Die and Let Live: Eliminating Dangerous Lymphocytes

1996 • 242 citations

Cotransplantation of Allogeneic Islets With Allogeneic Testicular Cell Aggregates Allows Long-Term Graft Survival Without Systemic Immunosuppression

1997 • 222 citations

Immunoreactive vasoactive intestinal peptide contributes to the immunosuppressive activity of normal aqueous humor.

1994 • 207 citations

Fluids from immune privileged sites endow macrophages with the capacity to induce antigen‐specific immune deviation via a mechanism involving transforming growth factor‐β

1992 • 206 citations

Amelioration of collagen-induced arthritis by CD95 (Apo-1/Fas)-ligand gene transfer.

1997 • 196 citations

Technical tips

1994 • 192 citations

Retrovirus-mediated transfer of viral IL-10 gene prolongs murine cardiac allograft survival.

1996 • 191 citations

Sertoli Cell-Enriched Fractions in Successful Islet Cell Transplantation

1993 • 172 citations

Apoptosis, fas and systemic autoimmunity: the MRL-Ipr/Ipr model

1994 • 151 citations

Adenovirus-mediated gene transfer of soluble vascular cell adhesion molecule to porcine interposition vein grafts.

1994 • 115 citations

Efficient Gene Transfer To Pancreatic Islets Mediated By Adenoviral Vectors

1995 • 89 citations

Efficient Gene Transfer To Pancreatic Islets Mediated By Adenoviral Vectors

1995 • 87 citations

FAS-MEDIATED CYTOTOXICITY AN IMMUNOEFFECTOR OR IMMUNOREGULATORY PATHWAY IN T CELL-MEDIATED IMMUNE RESPONSES?

1995 • 84 citations

Adenovirus-Mediated Expression of Fas Ligand Induces Hepatic Apoptosis after Systemic Administration and Apoptosis ofEx Vivo-Infected Pancreatic Islet Allografts and Isografts

1997 • 73 citations

Gene Transfer to the Thymus A Means of Abrogating the Immune Response to Recombinant Adenovirus

1995 • 72 citations

Neuropeptides modulate immune deviation induced via the anterior chamber of the eye.

1995 • 71 citations

Gene Transfer for Transplantation Prolongation of Allograft Survival with Transforming Growth Factor-β1

1994 • 66 citations

The immune response and the eye: a role for TNF alpha in anterior chamber-associated immune deviation.

1994 • 46 citations

INTERLEUKIN-4 OR INTERLEUKIN-10 EXPRESSED FROM ADENOVIRUS-TRANSDUCED SYNGENEIC ISLET GRAFTS FAILS TO PREVENT ?? CELL DESTRUCTION IN DIABETIC NOD MICE1

1997 • 44 citations

An Interleukin-1β Converting Enzyme-like Protease Is a Key Component of Fas-mediated Apoptosis

1996 • 35 citations

Adenoviral-mediated gene transfer to pancreatic islets does not alter islet function.

1994 • 22 citations

LIVER-DIRECTED GENE THERAPY

1996 • 8 citations

Expression of beta-galactosidase in mouse pancreatic islets by adenoviral-mediated gene transfer.

1995 • 6 citations