Influences of alpha-tocopherol on cholesterol metabolism and fatty streak development in apolipoprotein E-deficient mice fed an atherogenic diet

A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUES

1957 • 63,238 citations

Enzymatic Determination of Total Serum Cholesterol

1974 • 9,182 citations

Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells

1992 • 2,216 citations

Spontaneous Hypercholesterolemia and Arterial Lesions in Mice Lacking Apolipoprotein E

1992 • 2,189 citations

Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells.

1992 • 897 citations

Absorption, lipoprotein transport, and regulation of plasma concentrations of vitamin E in humans.

1993 • 591 citations

Vitamin E suppresses isoprostane generation in vivo and reduces atherosclerosis in ApoE-deficient mice

1998 • 509 citations

Effect of oral supplementation with D-alpha-tocopherol on the vitamin E content of human low density lipoproteins and resistance to oxidation.

1991 • 477 citations

Vitamin E: beyond antioxidant function

1995 • 371 citations

Direct spectrophotometry of total bile acids in serum.

1981 • 271 citations

Diet-induced atherosclerosis in mice heterozygous and homozygous for apolipoprotein E gene disruption.

1994 • 235 citations

Natural antioxidants in human health and disease

1995 • 218 citations

The Unexpected Role of Vitamin E (α-Tocopherol) in the Peroxidation of Human Low-Density Lipoprotein

1998 • 206 citations

Atherosclerosis, oxidative stress, and antioxidant protection in endothelium-derived relaxing factor action

1995 • 204 citations

Effect of selenium and vitamin E on the development of experimental atherosclerosis in rabbits

1991 • 178 citations

Increased Plasma and Lipoprotein Lipid Peroxidation in apo E-Deficient Mice

1994 • 172 citations

Dietary influences on membrane function: Importance in protection against oxidative damage and disease

1996 • 169 citations

Dietary vitamin E and the attenuation of early lesion development in modified Watanabe rabbits

1992 • 165 citations

Coantioxidants make alpha-tocopherol an efficient antioxidant for low-density lipoprotein

1995 • 136 citations

Identification, purification, and immunochemical characterization of a tocopherol-binding protein in rat liver cytosol.

1992 • 122 citations

Dietary Antioxidants Inhibit Development of Fatty Streak Lesions in the LDL Receptor–Deficient Mouse

1998 • 120 citations

Transgenic mouse models to study the role of APOE in hyperlipidemia and atherosclerosis

1998 • 91 citations

Antioxidant Protection of Low-Density Lipoprotein and Its Role in the Prevention of Atherosclerotic Vascular Disease

1994 • 81 citations

Vitamin E requirements, transport, and metabolism: Role of α-tocopherol-binding proteins

1994 • 75 citations

Effect of vitamin E on atherogenesis in LDL receptor-deficient rabbits

1995 • 62 citations

Dietary β-Carotene and α-Tocopherol Combination Does Not Inhibit Atherogenesis in an ApoE–Deficient Mouse Model

1999 • 59 citations

The Effect of Tocopherol on High-density Lipoprotein Cholesterol: A Clinical Observation

1979 • 58 citations

Effect of Vitamin E on Lipids

1983 • 53 citations

Determination of vitamin E in biological specimens and foods by HPLC- pretreatment of samples and extraction of tocopherols

1990 • 50 citations

beta-Carotene and alpha-tocopherol inhibit the development of atherosclerotic lesions in hypercholesterolemic rabbits.

1997 • 42 citations

Radical-induced lipoprotein and plasma lipid oxidation in normal and apolipoprotein E gene knockout (apoE–/–) mice: apoE–/– mouse as a model for testing the role of tocopherol-mediated peroxidation in atherogenesis

1998 • 36 citations

Prevention of Atherosclerosis with Dietary Antioxidants: Fact or Fiction?

1996 • 33 citations

Dietary Antioxidants Do Not Reduce Fatty Streak Formation in the C57BL/6 Mouse Atherosclerosis Model

1998 • 31 citations

Vitamin E Does Not Modify HDL-Cholesterol

1982 • 27 citations

Hypocholesterolemic effect of vitamin E on cholesterol-fed rabbit.

1990 • 16 citations

[The oxidative hypothesis of atherosclerosis and the use of antioxidants in coronary disease].

1997 • 7 citations