The need for indispensable amino acids: The concept of the anabolic drive

A rapid and convenient technique for measuring the rate of protein synthesis in tissues by injection of [3H]phenylalanine

1980 • 983 citations

Handbook of Physiology. Section- 2

1967 • 520 citations

Muscle Protein Synthesis Measured by Stable Isotope Techniques in Man: The Effects of Feeding and Fasting

1982 • 446 citations

Does leucine, leucyl-tRNA, or some metabolite of leucine regulate protein synthesis and degradation in skeletal and cardiac muscle?

1982 • 445 citations

Nutritional adaptation in man

1985 • 388 citations

The relative importance of muscle protein synthesis and breakdown in the regulation of muscle mass

1976 • 346 citations

Effect of Exercise on Protein Turnover in Man

1981 • 310 citations

Relationship between Protein Synthesis and RNA Content in Skeletal Muscle

1973 • 288 citations

A positive relationship between protein synthetic rate and intracellular glutamine concentration in perfused rat skeletal muscle

1987 • 285 citations

Insulin-like growth factors and insulin: comparative aspects

1985 • 262 citations

Hormonal regulation of protein degradation and synthesis in skeletal muscle.

1980 • 254 citations

Nitrogen metabolism in man.

1981 • 253 citations

Insulin-Like Growth Factors/Somatomedins: Structure, Secretion, Biological Actions and Physiological Role

1986 • 240 citations

Handbook of Physiology: Section 7: Endocrinology

1975 • 234 citations

Role of Insulin in the Regulation of Protein Synthesis

1980 • 234 citations

AMINO ACID REQUIREMENTS OF ADULT MAN

2009 • 218 citations

Relationship between glutamine concentration and protein synthesis in rat skeletal muscle

1988 • 206 citations

CHARACTERISTICS OF A GLUTAMINE CARRIER IN SKELETAL MUSCLE HAVE IMPORTANT CONSEQUENCES FOR NITROGEN LOSS IN INJURY, INFECTION, AND CHRONIC DISEASE

1986 • 206 citations

Potential of brown adipose tissue type II thyroxine 5'-deiodinase as a local and systemic source of triiodothyronine in rats.

1985 • 206 citations

Substrate and Energy Metabolism in Man

1985 • 180 citations

The nutritional role of indispensable amino acids and the metabolic basis for their requirements.

1988 • 158 citations

Failure of leucine to stimulate protein synthesis in vivo

1982 • 151 citations

Thyroid hormones control lysosomal enzyme activities in liver and skeletal muscle

1978 • 150 citations

Phosphorylation inhibits guanine nucleotide exchange on eukaryotic initiation factor 2

1982 • 141 citations

Catch-up Growth in Children

2009 • 135 citations

Effect of nutrition on protein turnover in skeletal muscle.

1978 • 133 citations

Protein Turnover, Synthesis and Breakdown before and after Recovery from Protein-Energy Malnutrition

1977 • 127 citations

Leucine kinetics at graded leucine intakes in young men

1986 • 126 citations

Relationship of Serum Immunoreactive Somatomedin-C to Dietary Protein and Energy in Growing Rats

1982 • 126 citations

The response of muscle protein synthesis to nutrient intake in postabsorptive rats: The role of insulin and amino acids

1986 • 120 citations

The role of insulin and thyroid hormones in the regulation of muscle growth and protein turnover in response to dietary protein in the rat

1988 • 117 citations

Lysine kinetics at graded lysine intakes in young men

1986 • 115 citations

The effect of T3 and reverse T3 administration on muscle protein catabolism during fasting as measured by 3-methylhistidine excretion

1979 • 111 citations

Ovine Somatomedin, Multiplication-Stimulating Activity, and Insulin Promote Skeletal Muscle Satellite Cell Proliferationin Vitro*

1985 • 111 citations

Specificity of the effects of leucine and its metabolites on protein degradation in skeletal muscle

1984 • 107 citations

Threonine kinetics at graded threonine intakes in young men

1986 • 105 citations

Intracellular protein catabolism

1997 • 99 citations

Effect of intravenous insulin treatment on in vivo whole body leucine kinetics and oxygen consumption in insulin-deprived type I diabetic patients

1987 • 97 citations

COLLAGEN AND NON–COLLAGEN PROTEIN TURNOVER IN SKELETAL MUSCLE OF GROWTH HORMONE–TREATED LAMBS

1987 • 96 citations

Energy and Protein Needs during Infancy

1987 • 87 citations

Effects of starvation, diabetes and acute insulin treatment on the regulation of polypeptide-chain initiation in rat skeletal muscle

1984 • 86 citations

Valine kinetics at graded valine intakes in young men

1986 • 85 citations

The role of insulin, corticosterone and other factors in the acute recovery of muscle protein synthesis on refeeding food-deprived rats

1983 • 84 citations

Thyroid hormones and muscle protein turnover. The effect of thyroid-hormone deficiency and replacement in thryoidectomized and hypophysectomized rats

1981 • 81 citations

Dose response of protein turnover in rat skeletal muscle to triiodothyronine treatment

1983 • 74 citations

The Measurement of Whole Body Protein Turnover in the Preterm Infant with Intragastric Infusion of <scp>l</scp>-[1-13C]Leucine and Sampling of the Urinary Leucine Pool

1984 • 73 citations

Triiodothyronine stimulates cartilage growth and maturation by different mechanisms

1987 • 69 citations

The effects of severe zinc deficiency on protein turnover in muscle and thymus

1987 • 67 citations

Effects of thyroxine on protein turnover in rat skeletal muscle.

1978 • 67 citations

Effect of Thyroid Hormone on Polypeptide Chain Assembly Kinetics in Liver Protein Synthesis in Vivo

1973 • 66 citations

Hormonal regulation of protein degradation in skeletal and cardiac muscle

1981 • 66 citations

The response of protein and energy metabolism to food intake in lean and obese man.

1982 • 64 citations

Degradative Processes in Heart and Skeletal Muscle

1981 • 60 citations

Thyroid hormone metabolism in primary cultured rat hepatocytes. Effects of glucose, glucagon, and insulin.

1981 • 57 citations

GROWTH HORMONE AND GROWTH IN MEAT PRODUCING ANIMALS

1986 • 55 citations

Muscle protein synthesis in the streptozotocin-diabetic rat. A possible role for corticosterone in the insensitivity to insulin infusion in vivo

1982 • 53 citations

The relative contribution of the nervous system, hormones, and metabolites to the total insulin response during a meal in the rat

1984 • 53 citations

Nitrogen Balance of Men Fed Amino Acid Mixtures Based on Rose's Requirements, Egg White Protein, and Serum Free Amino Acid Patterns

1971 • 50 citations

Modulation of rat skeletal muscle branched-chain alpha-keto acid dehydrogenase in vivo. Effects of dietary protein and meal consumption.

1987 • 45 citations

Regulatory role of dietary leucine on plasma branched-chain amino acid levels in young men.

1976 • 44 citations

The mechanism of recovery of hepatic T4-5′-deiodinase during glucose-refeeding: Role of glucagon and insulin

1983 • 39 citations

Temperature dependency of protein synthesis in toadfish liver in vivo

1978 • 34 citations

Influence of zinc on growth, somatomedin, and glycosaminoglycan metabolism in rats

1987 • 31 citations

EFFECTS OF β-ADRENERGIC AGONISTS ON METABOLISM AND BODY COMPOSITION

1986 • 28 citations

The effect of dietary protein and energy restriction on heat production and growth costs in the young rat

1987 • 28 citations

Protein Degradation and the Regulation of Protein Balance in Muscle

1980 • 22 citations

Protein turnover in the whole animal.

1980 • 22 citations

The physiological regulation of proteolysis in muscle

1985 • 22 citations

Regulation of Ca2+-dependent protein turnover in skeletal muscle by thyroxine

1986 • 21 citations

The effect of tri-iodothyronine administration on protein synthesis in the diabetic rat

1983 • 20 citations

Adrenergic modulation of insulin secretion in vivo dependent on thyroid states.

1978 • 20 citations

Role of thyroid, insulin and corticosteroid hormones in the physiological regulation of proteolysis in muscle.

1985 • 20 citations

The influence of plasma concentrations of tri-iodothyronine on the acute increases in insulin and muscle protein synthesis in the refed fasted rat

1988 • 17 citations

Hormonal changes in normal men under marginally negative energy balance

1984 • 17 citations

Muscle protein synthesis: regulation of a translational inhibitor

1984 • 12 citations

The role of metabolites of arachidonic acid in the physiology and pathophysiology of muscle protein metabolism

1987 • 10 citations

Changes in the Relative Rates of Protein Synthesis and Breakdown during Muscle Growth and Atrophy

1978 • 9 citations

IGF-1 concentrations in protein deficient rat plasma and tissues in relation to protein and proteoglycan synthesis rates

1988 • 6 citations

Regulation of hepatic aromatic amino acid metabolism

1986 • 3 citations

Dietary and hormonal influences on plasma igf 1 levels in the rat

1987 • 2 citations