Dissection of the HLA association with multiple sclerosis in the founder isolated population of Sardinia

New diagnostic criteria for multiple sclerosis: Guidelines for research protocols

1983 • 7,404 citations

Performing the Exact Test of Hardy-Weinberg Proportion for Multiple Alleles

1992 • 4,934 citations

Gametic Disequilibrium Measures: Proceed With Caution

1987 • 930 citations

On measures of gametic disequilibrium.

1988 • 727 citations

A full genome search in multiple sclerosis

1996 • 666 citations

A complete genomic screen for multiple sclerosis underscores a role for the major histocompatability complex

1996 • 650 citations

A genome screen in multiple sclerosis reveals susceptibility loci on chromosome 6p21 and 17q22

1996 • 638 citations

A genetic basis for familial aggregation in multiple sclerosis

1995 • 626 citations

An extended transmission/disequilibrium test (TDT) for multi‐allele marker loci

1995 • 624 citations

Allelic sequence variation of the HLA-DQ loci: relationship to serology and to insulin-dependent diabetes susceptibility.

1988 • 378 citations

Mapping disease genes: family-based association studies.

1995 • 345 citations

Genomewide Scan of Multiple Sclerosis in Finnish Multiplex Families

1997 • 308 citations

Epidemiology of Multiple Sclerosis: A Critical Overview

1993 • 306 citations

Multiple sclerosis: a modifying influence of HLA class I genes in an HLA class II associated autoimmune disease

2000 • 284 citations

Highly Informative Typing of the Human TNF Locus Using Six Adjacent Polymorphic Markers

1993 • 273 citations

HLA-DR15 is associated with lower age at onset in multiple sclerosis

2000 • 258 citations

MHC haplotype-dependent regulation of MOG-induced EAE in rats.

1998 • 257 citations

Age–adjusted recurrence risks for relatives of patients with multiple sclerosis

1996 • 227 citations

Alleles and haplotypes of the MHC-encoded ABC transporters TAP1 and TAP2

1993 • 217 citations

High resolution analysis of haplotype diversity and meiotic crossover in the human TAP2 recombination hotspot

2000 • 209 citations

Relative predispositional effects (RPEs) of marker alleles with disease: HLA-DR alleles and Graves disease.

1989 • 193 citations

Rapid HLA-DPB typing using enzymatically amplified DNA and nonradioactive sequence-specific oligonucleotide probes

1990 • 189 citations

A correlation between the relative predisposition of MHC class II alleles to type 1 diabetes and the structure of their proteins

2001 • 185 citations

Alleles at four HLA class II loci determined by oligonucleotide hybridization and their associations in five ethnic groups

1991 • 169 citations

Major histocompatibility complex class II alleles and the course and outcome of MS

1998 • 150 citations

Multiple sclerosis : clinical and pathogenetic basis

1997 • 135 citations

Multiple sclerosis is associated with genes within or close to the HLA‐DR‐DQ subregion on a normal DR15, DQ6, Dw2 haplotype

1993 • 133 citations

DRB1-DQA1-DQB1 loci and multiple sclerosis predisposition in the Sardinian population

1998 • 131 citations

Major factors influencing linkage disequilibrium by analysis of different chromosome regions in distinct populations: demography, chromosome recombination frequency and selection

2000 • 130 citations

Risks of multiple sclerosis in relatives of patients in Flanders, Belgium.

1997 • 111 citations

The increasing incidence and prevalence of MS in a Sardinian province

2000 • 108 citations

Recombination within the human MHC

1999 • 105 citations

A meta-analysis of genomic screens in multiple sclerosis

2001 • 95 citations

Significant Admixture Linkage Disequilibrium across 30 cM around the FY Locus in African Americans

2000 • 93 citations

Evaluation of fine mapping strategies for a multifactorial disease locus: systematic linkage and association analysis of IDDM1 in the HLA region on chromosome 6p21

2000 • 90 citations

HLA-DR and -DQ Associations with Multiple Sclerosis in Turkey

1997 • 90 citations

Extended major histocompatibility complex haplotypes in patients with multiple sclerosis

1989 • 88 citations

HLA-DR typing using DNA amplification by the polymerase chain reaction and sequential hybridization to sequence-specific oligonucleotide probes

1990 • 88 citations

Microsatellites in the HLA region: 1999 update

2000 • 83 citations

HLA Class II Susceptibility to Multiple Sclerosis Among Ashkenazi and Non-Ashkenazi Jews

1999 • 79 citations

Evidence of Linkage with HLA-DR in DRB1*15-Negative Families with Multiple Sclerosis

2001 • 77 citations

Both the HLA‐DPB1 and ‐DRB1 alleles correlate with risk for multiple sclerosis in Japanese: clinical phenotypes and gender as important factors

2000 • 70 citations

The inter-regional distribution of HLA class II haplotypes indicates the suitability of the Sardinian population for case-control association studies in complex diseases

2000 • 68 citations

Adaptation of the extended transmission/disequilibrium test to distinguish disease associations of multiple loci: the Conditional Extended Transmission/Disequilibrium Test

2000 • 67 citations

The distribution of HLA class II haplotypes reveals that the Sardinian population is genetically differentiated from the other Caucasian populations

2000 • 66 citations

Clinical Features of Multiple Sclerosis

1985 • 52 citations

HLA class II genotypes in Mexican Mestizos with familial and nonfamilial multiple sclerosis

2000 • 49 citations

HLA-DP: A Class II Restriction Molecule Involved in Epitope Spreading During the Development of Multiple Sclerosis

1998 • 43 citations

Microsatellites in the HLA region: 1998 update

1998 • 39 citations

Heat shock protein 70 gene polymorphisms in rheumatoid arthritis

1997 • 31 citations

HLA‐DPB1 alleles correlate with risk for multiple sclerosis in Caucasoid and Cantonese patients lacking the high‐risk DQB1*0602 allele

1993 • 27 citations

Confirmation of the DRB1-DQB1 loci as the major component of IDDM1 in the isolated founder population of Sardinia

2000 • 24 citations

Evidence for the genetic role of human leukocyte antigens in low frequency DRBI*1501 multiple sclerosis patients in Israel

1999 • 18 citations

Mapping of 10 novel microsatellites in the MHC class III region: application to the study of autoimmune disease.

1997 • 18 citations

Polymorphic tri and tetranucleotide repeats in exons 1 and 8 of the myelin oligodendrocyte glycoprotein (MOG) gene

1995 • 18 citations

Inheritance of susceptibility to multiple sclerosis

1998 • 17 citations

Absence of primary association between DM gene polymorphism and insulin-dependent diabetes mellitus or celiac disease

1996 • 16 citations

Deleted Work

1955 • 0 citations