A derivative of amiloride blocks both the light-regulated and cyclic GMP-regulated conductances in rod photoreceptors.

Induction by cyclic GMP of cationic conductance in plasma membrane of retinal rod outer segment

1985 • 1,213 citations

The membrane current of single rod outer segments

1979 • 486 citations

Cyclic GMP-sensitive conductance of retinal rods consists of aqueous pores

1986 • 336 citations

Single cyclic GMP-activated channel activity in excised patches of rod outer segment membrane

1986 • 335 citations

Pyrazine Diuretics. II. N-Amidino-3-amino-5-substituted 6-Halopyrazinecarboxamides

1967 • 323 citations

The ionic selectivity and calcium dependence of the light‐sensitive pathway in toad rods.

1985 • 269 citations

A voltage‐clamp study of the light response in solitary rods of the tiger salamander.

1979 • 241 citations

Identification, purification, and functional reconstitution of the cyclic GMP-dependent channel from rod photoreceptors.

1987 • 239 citations

Cyclic GMP directly regulates a cation conductance in membranes of bovine rods by a cooperative mechanism.

1985 • 230 citations

Cation selectivity of light-sensitive conductance in retinal rods

1984 • 205 citations

Structure-activity relationships of amiloride and certain of its analogues in relation to the blockade of the Na+/H+ exchange system.

1984 • 204 citations

Control of the light-regulated current in rod photoreceptors by cyclic GMP, calcium, and l-cis-diltiazem.

1986 • 180 citations

Membrane conductances of photoreceptors

1981 • 159 citations

Patch‐clamp recordings of the light‐sensitive dark noise in retinal rods from the lizard and frog.

1985 • 147 citations

Characterization of potent sodium/proton exchange inhibitors from the amiloride series in A431 cells

1984 • 144 citations

Inhibition of sodium-calcium exchange in pituitary plasma membrane vesicles by analogs of amiloride

1985 • 137 citations

Fast Ionic Flux Activated by Cyclic GMP in the Membrane of Cattle Rod Outer Segments

1983 • 107 citations

Sodium‐calcium exchange in the outer segments of bovine rod photoreceptors.

1986 • 102 citations

cGMP-dependent cation channel of retinal rod outer segments

1987 • 94 citations

Topology of the Outer Segment Membranes of Retinal Rods and Cones Revealed by a Fluorescent Probe

1974 • 84 citations

Control of the generator current in solitary rods of the Ambystoma tigrinum retina.

1984 • 79 citations

Frog rod outer segments with attached inner segment ellipsoids as an in vitro model for photoreceptors on the retina.

1985 • 72 citations

Single-channel recordings demonstrate that cGMP opens the light-sensitive ion channel of the rod photoreceptor.

1987 • 71 citations

Ionic movements through light‐sensitive channels of toad rods.

1983 • 68 citations

Transduction persists in rod photoreceptors after depletion of intracellular calcium.

1987 • 57 citations

Kinetics of light-sensitive channels in vertebrate photoreceptors

1985 • 57 citations

THE SHARPEY‐SCHAFER LECTURE ION CHANNELS AND SIGNAL PROCESSING IN THE OUTER RETINA

1986 • 54 citations

Protons suppress the dark current of frog retinal rods.

1984 • 53 citations

Na+- and cGMP-induced Ca2+ fluxes in frog rod photoreceptors.

1987 • 36 citations

Incorporation of ion channels from bovine rod outer segments into planar lipid bilayers

1984 • 17 citations

Membrane potential affects photocurrent kinetics in salamander rods and cones

1984 • 4 citations

Quantitative Models of Phototransduction

1986 • 1 citations

Light-sensitive Channels, Pumps, and Carriers

1986 • 1 citations