Prospective Comparison of Whole-Blood- and Plasma-Based Hepatitis C Virus RNA Detection Systems: Improved Detection Using Whole Blood as the Source of Viral RNA

Isolation of a cDNA cLone Derived from a Blood-Borne Non-A, Non-B Viral Hepatitis Genome

1989 • 6,910 citations

Viral Hepatitis and Liver Disease

1985 • 1,886 citations

The Natural History of Community-Acquired Hepatitis C in the United States

1992 • 1,614 citations

A Role for Hepatitis C Virus Infection in Type II Cryoglobulinemia

1992 • 1,302 citations

Epidemiology of hepatitis C

1997 • 1,112 citations

Hepatitis C: The clinical spectrum of disease

1997 • 768 citations

Routes of Infection, Viremia, and Liver Disease in Blood Donors Found to Have Hepatitis C Virus Infection

1996 • 649 citations

Statistical Methods for the Analysis of Biomedical Data

1989 • 602 citations

Variability of hepatitis C virus

1995 • 561 citations

Hepatitis C Virus Infection in Post-Transfusion Hepatitis

1991 • 538 citations

Confirmation of hepatitis C virus infection by new four-antigen recombinant immunoblot assay

1991 • 509 citations

DNA polymerase fidelity and the polymerase chain reaction.

1991 • 441 citations

Natural history of hepatitis C

1997 • 419 citations

Diagnostic tests for hepatitis C

1997 • 321 citations

The molecular virology of hepatitis C

1997 • 319 citations

Specific detection of hepatitis C virus minus strand RNA in hematopoietic cells.

1996 • 273 citations

Lack of detection of negative-strand hepatitis C virus RNA in peripheral blood mononuclear cells and other extrahepatic tissues by the highly strand-specific rTth reverse transcriptase PCR

1995 • 258 citations

Natural history of hepatitis C

1999 • 243 citations

Density heterogeneities of hepatitis C virus in human sera due to the binding of ?-lipoproteins and immunoglobulins

1993 • 228 citations

Assessment of Hepatitis C Virus RNA Levels by Quantitative Competitive RNA Polymerase Chain Reaction: High-Titer Viremia Correlates with Advanced Stage of Disease

1994 • 219 citations

Hepatitis C Virus Is Detected in a Monocyte/Macrophage Subpopulation of Peripheral Blood Mononuclear Cells of Infected Patients

1992 • 183 citations

A role for hepatitis C virus infection in type II cryoglobulinemia Agnello V., Chung R.T., Kaplan L.M. N Engl J Med 1992;327:1490–1495

1993 • 168 citations

Sensitivity of serological assays to identify blood donors with hepatitis C viraemia

1992 • 154 citations

Detection of Chronic Hepatitis C Virus Infection by Four Diagnostic Systems: First–Generation and Second–Generation Enzyme–Linked Immunosorbent Assay, Second–Generation Recombinant Immunoblot Assay and Nested Polymerase Chain Reaction Analysis

1992 • 99 citations

Diagnosis of hepatitis C

1997 • 86 citations

Hepatitis C virus negative strand RNA is not detected in peripheral blood mononuclear cells and viral sequences are identical to those in serum: a case against extrahepatic replication.

1997 • 79 citations

Hepatic and extrahepatic HCV RNA strands in chronic hepatitis C: Different patterns of response to interferon treatment

1993 • 73 citations

Characterization of Hepatitis G Virus (GB-C Virus) Particles: Evidence for a Nucleocapsid and Expression of Sequences Upstream of the E1 Protein

1998 • 72 citations

Surreptitious Hepatitis C Virus (HCV) Infection Detected in the Majority of Patients with Cryptogenic Chronic Hepatitis and Negative HCV Antibody Tests

1997 • 71 citations

Distribution of Hepatitis C Virus (HCV) RNA in Whole Blood and Blood Cell Fractions: Plasma HCV RNA Analysis Underestimates Circulating Virus Load

1997 • 70 citations

Detection of Hepatitis G Virus Replication Sites by Using Highly Strand-Specific Tth-Based Reverse Transcriptase PCR

1998 • 68 citations

Infectious disease testing for blood transfusions. NIH Consensus Development Panel on Infectious Disease Testing for Blood Transfusions

1995 • 66 citations

Quantitative PCR

1995 • 65 citations

Infectious Disease Testing for Blood Transfusions

1995 • 58 citations

Enhanced Sensitivity of a Second Generation ELISA for Antibody to Hepatitis C Virus

1992 • 50 citations

Direct detection of hepatitis C virus (HCV) RNA from whole blood, and comparison with HCV RNA in plasma and peripheral blood mononuclear cells

1995 • 45 citations

HCV RNA in serum of asymptomatic blood donors involved in post-transfusion hepatitis (PTH)

1991 • 40 citations

Quantitative analysis in molecular diagnostics

1994 • 37 citations

Differences in the regulation of cytochrome P450 family members during liver regeneration

1997 • 33 citations

Effect of interferon therapy on hepatitis C virus RNA in whole blood, plasma, and peripheral blood mononuclear cells

1998 • 32 citations

Determination of Hepatitis C Virus RNA in the Serum by the Amplicor HCV PCR Kit

1994 • 19 citations

Quantitative PCR: A Survey of the Present Technology

2003 • 17 citations

Improved Detection of Antibodies to Hepatitis C Virus Using a Second Generation Elisa

1992 • 13 citations

Tests help nail down HCV--but not entirely

1991 • 6 citations

Tests Help Nail Down HCV—but Not Entirely

1991 • 5 citations