Cutting Edge: A Natural P451L Mutation in the Cytoplasmic Domain Impairs the Function of the Mouse P2X7 Receptor

Prediction of Protein Secondary Structure at Better than 70% Accuracy

1993 • 2,958 citations

The Cytolytic P _2Z Receptor for Extracellular ATP Identified as a P _2X Receptor (P2X ₇ )

1996 • 1,703 citations

Extracellular ATP: effects, sources and fate

1986 • 1,666 citations

Purinoceptors: Are there families of P2X and P2Y purinoceptors?

1994 • 1,079 citations

Altered Cytokine Production in Mice Lacking P2X7Receptors

2001 • 918 citations

Connexins regulate calcium signaling by controlling ATP release

1998 • 767 citations

Nucleotide receptors: an emerging family of regulatory molecules in blood cells

2001 • 724 citations

Pharmacology of Cloned P2X Receptors

2000 • 701 citations

Extracellular ATP triggers IL-1 beta release by activating the purinergic P2Z receptor of human macrophages.

1997 • 606 citations

Absence of the P2X7 Receptor Alters Leukocyte Function and Attenuates an Inflammatory Response

2002 • 492 citations

The Permeabilizing ATP Receptor, P2X7

1997 • 486 citations

The P2Z purinoceptor: an intriguing role in immunity, inflammation and cell death

1995 • 378 citations

Proteomic and functional evidence for a P2X7 receptor signalling complex

2001 • 376 citations

A Glu-496 to Ala Polymorphism Leads to Loss of Function of the Human P2X7 Receptor

2001 • 311 citations

P2Z purinoreceptor ligation induces activation of caspases with distinct roles in apoptotic and necrotic alterations of cell death

1999 • 276 citations

Extracellular ATP in T-lymphocyte activation: possible role in effector functions.

1990 • 196 citations

Extracellular nucleotides mediate Ca2+ fluxes in J774 macrophages by two distinct mechanisms.

1988 • 189 citations

Cutting Edge: The Nucleotide Receptor P2X7 Contains Multiple Protein- and Lipid-Interaction Motifs Including a Potential Binding Site for Bacterial Lipopolysaccharide

2001 • 180 citations

Responses of mouse lymphocytes to extracellular adenosine 5'-triphosphate (ATP). Lymphocytes with cytotoxic activity are resistant to the permeabilizing effects of ATP.

1989 • 178 citations

A loss-of-function polymorphic mutation in the cytolytic P2X7 receptor gene and chronic lymphocytic leukaemia: a molecular study

2002 • 163 citations

Cloning and functional characterisation of the mouse P2X₇ receptor

1998 • 146 citations

Extracellular ATP induces a large nonselective conductance in macrophage plasma membranes.

1988 • 134 citations

Cutting Edge: Purinergic Signaling Regulates Radical-Mediated Bacterial Killing Mechanisms in Macrophages Through a P2X7-Independent Mechanism

1999 • 121 citations

Extracellular ATP as a possible mediator of cell-mediated cytotoxicity

1990 • 120 citations

Cystic Fibrosis Transmembrane Conductance Regulator–associated ATP Release Is Controlled by a Chloride Sensor

1998 • 109 citations

Complexities of measuring antagonist potency at P2X(7) receptor orthologs.

2001 • 73 citations

Apparent species differences in the kinetic properties of P2X₇ receptors

2000 • 73 citations

Rapid Induction of Naive T Cell Apoptosis by Ecto-Nicotinamide Adenine Dinucleotide: Requirement for Mono(ADP-Ribosyl)Transferase 2 and a Downstream Effector

2001 • 64 citations

Metalloprotease-Mediated Shedding of Enzymatically Active Mouse ecto-ADP-ribosyltransferase ART2.2 Upon T Cell Activation

2000 • 61 citations

Role of extracellular adenosine triphosphate in the cytotoxic T- lymphocyte-mediated lysis of antigen presenting cells

1995 • 58 citations

Ecto‐enzymes of lymphoid cells

1998 • 57 citations

Solution structure of the tumor necrosis factor receptor-1 death domain

2001 • 45 citations

Species- and agonist-dependent differences in the deactivation-kinetics of P2X 7 receptors

2001 • 32 citations

Permittivity of a multiphase and isotropic lattice of spheres at low frequency

2000 • 29 citations

Chronic oral administration of ATP modulates nucleoside transport and purine metabolism in rats.

2000 • 25 citations

Cardiovascular and pulmonary response to oral administration of ATP in rabbits

2000 • 18 citations