Human cholesterol synthesis measurement using deuterated water. Theoretical and procedural considerations.

Fatty acid synthesis in adipose tissue incubated in tritiated water

1968 • 390 citations

Measurement of de novo hepatic lipogenesis in humans using stable isotopes.

1991 • 364 citations

Turnover of plasma cholesterol in man

1968 • 295 citations

Correlation between serum levels of some cholesterol precursors and activity of HMG-CoA reductase in human liver

1987 • 270 citations

DEUTERIUM AS AN INDICATOR IN THE STUDY OF INTERMEDIARY METABOLISM

1937 • 257 citations

Low-density lipoprotein receptor activity in cultured human skin fibroblasts. Mechanism of insulin-induced stimulation.

1979 • 245 citations

Regulation of rates of cholesterol synthesis in vivo in the liver and carcass of the rat measured using [3H]water.

1980 • 228 citations

Measurement of rates of cholesterol synthesis using tritiated water

1984 • 204 citations

Evidence for diurnal periodicity in human cholesterol synthesis.

1990 • 181 citations

Absolute rates of cholesterol synthesis in extrahepatic tissues measured with 3H-labeled water and 14C-labeled substrates.

1979 • 160 citations

Limitations of Acetate as a Substrate for Measuring Cholesterol Synthesis in Liver

1974 • 144 citations

Regulation of cholesterol metabolism in man and in other species

1984 • 125 citations

Measurement of rate of rat liver sterol synthesis in vivo using tritiated water.

1977 • 114 citations

Transport of cholesterol

1983 • 107 citations

ERYTHROCYTE METABOLISM. THE METABOLIC BEHAVIOR OF THE CHOLESTEROL OF HUMAN ERYTHROCYTES 1

1953 • 98 citations

Determination of mevalonate in blood plasma in man and rat. Mevalonate “tolerance” tests in man.

1979 • 96 citations

Prediction of the parameters of whole body cholesterol metabolism in humans.

1980 • 96 citations

The use of C14-labeled acetate to study cholesterol metabolism in man.

1955 • 89 citations

Validation of saliva sampling for total body water determination by H 2 18 O dilution

1982 • 71 citations

The Turnover of Squalene in Relation to the Biosynthesis of Cholesterol

1958 • 67 citations

Whole body and hepatic cholesterol synthesis rates in the guinea-pig: effect of dietary fat quality

1990 • 55 citations

Human serum cholesterol synthesis measured with the deuterium label.

1966 • 54 citations

Decreased cholesterol biosynthesis in sitosterolemia with xanthomatosis: Diminished mononuclear leukocyte 3-hydroxy-3-methylglutaryl coenzyme a reductase activity and enzyme protein associated with increased low-density lipoprotein receptor function

1990 • 48 citations

The relationship between the rate of hepatic sterol synthesis and the incorporation of [3H]water.

1983 • 35 citations

Cholesterol turnover in human plasma lipoproteins: studies with stable and radioactive isotopes

1982 • 34 citations

Ethanol metabolism and lipid synthesis by isolated liver cells from fed rats

1976 • 31 citations

Measurement of in vivo cholesterol synthesis from 2H2O: a rapid procedure for the isolation, combustion, and isotopic assay of erythrocyte cholesterol.

1991 • 27 citations

Cholesterol and triglyceride fatty acid synthesis in apolipoprotein E2-associated hyperlipidemia.

1992 • 20 citations

Association between apolipoprotein E phenotype and endogenous cholesterol synthesis as measured by deuterium uptake

1991 • 11 citations

Origin and fate of rat plasma cholesterol in vivo. Modelling of cholesterol movements between plasma and organs

1987 • 8 citations