Comparison of promoter suppression in avian and murine retrovirus vectors

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter.

1982 • 2,753 citations

Chromosomal Subunits in Active Genes Have an Altered Conformation

1976 • 1,842 citations

Assembly and propagation of repressed and derepressed chromosomal states

1985 • 518 citations

New procedure for DNA transfection with polycation and dimethyl sulfoxide.

1984 • 481 citations

Genes with promoters in retrovirus vectors can be independently suppressed by an epigenetic mechanism

1984 • 440 citations

Nucleotide sequence of the thymidine kinase gene of herpes simplex virus type 1.

1981 • 388 citations

Transcriptional interference in avian retroviruses—implications for the promoter insertion model of leukaemogenesis

1984 • 368 citations

Promoter occlusion: Transcription through a promoter may inhibit its activity

1982 • 294 citations

Transcriptional "silencer" element in rat repetitive sequences associated with the rat insulin 1 gene locus.

1986 • 257 citations

Expression of transfected DNA depends on DNA topology

1986 • 246 citations

New Procedure for DNA Transfection with Polycation and Dimethyl Sulfoxide

1984 • 217 citations

Induction of altered chromatin structures by simian virus 40 enhancer and promoter elements

1984 • 217 citations

Construction of a helper cell line for avian reticuloendotheliosis virus cloning vectors.

1983 • 214 citations

Retrovirus-mediated transfer of human adenosine deaminase gene sequences into cells in culture and into murine hematopoietic cells in vivo.

1986 • 194 citations

Biochemical Studies on the Herpes Simplex Virus-specified Deoxypyrimidine Kinase Activity

1974 • 190 citations

Hb switching in chickens

1980 • 189 citations

Adaptation of a retrovirus as a eucaryotic vector transmitting the herpes simplex virus thymidine kinase gene.

1982 • 157 citations

Quantitative analysis of gene suppression in integrated retrovirus vectors.

1986 • 155 citations

Long terminal repeat of murine retroviral DNAs: sequence analysis, host-proviral junctions, and preintegration site

1982 • 154 citations

Hybrid plasmids containing an active thymidine kinase gene of Herpes simplex virus 1

1979 • 147 citations

Retrovirus-induced lethal mutation in collagen I gene of mice is associated with an altered chromatin structure

1984 • 126 citations

Transformation mediated by the SV40 T antigens: Separation of the overlapping SV40 early genes with a retroviral vector

1984 • 121 citations

Retrovirus insertion inactivates mouse α 1(I) collagen gene by blocking initiation of transcription

1986 • 118 citations

Amphotropic retrovirus vector system for human cell gene transfer.

1984 • 117 citations

Cell killing by spleen necrosis virus is correlated with a transient accumulation of spleen necrosis virus DNA

1979 • 105 citations

Construction of a Helper Cell Line for Avian Reticuloendotheliosis Virus Cloning Vectors

1983 • 99 citations

Infectious and Selectable Retrovirus Containing an Inducible Rat Growth Hormone Minigene

1984 • 99 citations

Transfer of genes into embryonal carcinoma cells by retrovirus infection: efficient expression from an internal promoter.

1985 • 94 citations

Cell-specified expression of a selectable hybrid gene.

1984 • 69 citations

Construction of a retrovirus capable of transducing and expressing genes in multipotential embryonic cells.

1984 • 66 citations

Role of intron-contained sequences in formation of moloney murine leukemia virus env mRNA.

1984 • 62 citations

Transmission of the polyoma virus middle T gene as the oncogene of a murine retrovirus

1984 • 59 citations

Amphotropic Retrovirus Vector System for Human Cell Gene Transfer

1984 • 55 citations

Insertion of several different DNAs in reticuloendotheliosis virus strain T suppresses transformation by reducing the amount of subgenomic mRNA

1986 • 53 citations

Integration-specific retrovirus expression in embryonal carcinoma cells.

1984 • 53 citations

Quantitative Analysis of Gene Suppression in Integrated Retrovirus Vectors

1986 • 49 citations

Retrovirus transduction: segregation of the viral transforming function and the herpes simplex virus tk gene in infectious Friend spleen focus-forming virus thymidine kinase vectors.

1983 • 48 citations

Interaction in vivo between strong closely spaced constitutive promoters

1979 • 43 citations

Isolation of embryonal carcinoma cell lines that express integrated recombinant genes flanked by the Moloney murine leukemia virus long terminal repeat.

1985 • 40 citations

Template Structural Requirements for Transcription In Vivo by RNA Polymerase II

1982 • 38 citations

Template Structural Requirements for Transcription In Vivo by RNA Polymerase II

1982 • 32 citations

Role of Intron-Contained Sequences in Formation of Moloney Murine Leukemia Virus env mRNA

1984 • 30 citations

Pseudotyped retroviral vectors reveal restrictions to reticuloendotheliosis virus replication in rat cells

1986 • 23 citations

Retrovirus Transduction: Segregation of the Viral Transforming Function and the Herpes Simplex Virus tk Gene in Infectious Friend Spleen Focus-Forming Virus Thymidine Kinase Vectors

1983 • 16 citations