Pharmacological properties of some “second generation” antidepressant drugs

Development of β-adrenergic receptor subsensitivity by antidepressants

1977 • 727 citations

Diagnosis and Drug Treatment of Psychiatric Disorders

1970 • 534 citations

Presynaptic modulation of beta adrenergic receptors in rat cerebral cortex after treatment with antidepressants.

1978 • 440 citations

A possible common mechanism of action of antidepressant treatments

1976 • 410 citations

Zimelidine

1982 • 385 citations

Presynaptic Alpha-Receptor Subsensitivity After Long-Term Antidepressant Treatment

1978 • 320 citations

Mianserin

1978 • 301 citations

Nomifensine: a new potent inhibitor of dopamine uptake into synaptosomes from rat brain corpus striatum

1974 • 289 citations

Uptake inhibition of biogenic amines by newer antidepressant drugs: Relevance to the dopamine hypothesis of depression

1977 • 264 citations

Indoleamine metabolites in the cerebrospinal fluid of depressed patients before and during treatment with nortriptyline

1973 • 242 citations

Presynaptic receptor systems in catecholaminergic transmission

1977 • 239 citations

Blockade of presynaptic ?-receptors and of amine uptake in the rat brain by the antidepressant mianserine

1977 • 207 citations

Norepinephrine Metabolites as Biochemical Criteria for Classifying Depressive Disorders and Predicting Responses to Treatment: Preliminary Findings

1973 • 204 citations

Effects of chronic desipramine treatment on rat brain noradrenergic responses to α-adrenergic drugs

1980 • 187 citations

Plasma protein binding of tricyclic anti-depressants in man

1969 • 184 citations

Inhibition of the neuronal uptake of 5-hydroxytryptamine and noradrenaline in rat brain by (Z)- and (E)-3-(4-Bromophenyl)-N,N-dimethyl-3-(3-pyridyl) allylamines and their secondary analogues

1977 • 170 citations

Depression and MHPG Excretion

1972 • 150 citations

Growth Hormone Responses in Depressive Illness

1971 • 150 citations

New perspectives on the mode of action of antidepressant drugs

1979 • 148 citations

Central serotonin metabolism and frequency of depression

1979 • 136 citations

Functional Aspects of the Norepinephrine Receptor Coupled Adenylate Cyclase System in the Limbic Forebrain and its Modification by Drugs which Precipitate or Alleviate Depression: Molecular Approaches to an Understanding of Affective Disorders

1978 • 132 citations

Beta-adrenergic receptor function in affective illness

1979 • 130 citations

Mianserin hydrochloride: Peripheral and central effects in relation to antagonism against 5-hydroxytryptamine and tryptamine

1971 • 125 citations

Psychoactive drug effects on a system which generates cyclic AMP in brain

1976 • 124 citations

β-Adrenergic Regulation of α ₃ -Adrenergic Receptors in the Central Nervous System

1980 • 118 citations

Zimelidine: A therapeutic and pharmacokinetic study in depression

1979 • 115 citations

Trazodone, a central serotonin antagonist and agonist

1979 • 114 citations

Potent and long-lasting potentiation of two 5-hydroxytryptophan-induced effects in mice by three selective 5-HT uptake inhibitors

1978 • 98 citations

Different central effects of the 5-HT antagonists mianserine and cyproheptadine.

1972 • 90 citations

Differential effect of chlorimipramine and nortriptyline on cerebrospinal fluid metabolites of serotonin and noradrenaline in depression

1974 • 89 citations

Excretion of MHPG in Normal Subjects

1978 • 88 citations

Controlled study comparing nomifensine and clomipramine in unipolar depression, using the probenecid technique.

1977 • 74 citations

Some effects of a new tetracyclic anti-depressant compound, Org GB 94, on the metabolism of monoamines in the rat brain

1974 • 70 citations

The effect of nomifensine on the depletion of brain serotonin and catecholamines induced respectively by fenfluramine and 6-hydroxydopamine in rats

1975 • 69 citations

The effects of mianserin hydrochloride on the vascular responses evoked by 5-hydroxytryptamine and related vasoactive substances

1971 • 63 citations

Effects of trazodone on serotonin in the brain and platelets of the rat

1976 • 55 citations

A comparison of the acute and chronic effects of four antidepressant drugs on the turnover of serotonin, dopamine and noradrenaline in the rat brain

1976 • 54 citations

Effect of nomifensine and other antidepressant drugs on acetylcholine turnover in various regions of rat brain

1978 • 53 citations

Mianserin: a decade of scientific development.

1978 • 52 citations

The effect of a tetracyclic antidepressant compound, Org GB94, on the turnover of biogenic amines in rat brain

1976 • 45 citations

Chronic effects of miaserin on noradrenaline metabolism in the rat brain: Evidence for a pre-synaptic ?-adrenolytic action in vivo

1979 • 43 citations

The effect of etoperidone, a new potential antidepressant drug, on the central serotonin system

1979 • 34 citations

Nomifensine in Parkinson's disease.

1977 • 32 citations

Central nervous system depressant actions of clonidine and UK‐14,304: partial dissociation of EEG and behavioural effects.

1978 • 28 citations

Pharmacokinetics of zimelidine

1980 • 26 citations

Further aspects of nomifensine pharmacology.

1977 • 25 citations

On the central antiserotonin action of trazodone.

1979 • 25 citations

Assessment of Age, Sex, and Height from Immature Human Bones

1958 • 22 citations

Evidence for the role of noradrenaline in some effects of quipazine

1980 • 21 citations

Nomifensine in parkinsonism.

1977 • 20 citations

Effects of nomifensine, an inhibitor of endogenous catecholamine re‐ uptake, in acromegaly, in hyperprolactinaemia, and against stimulated prolactin release in man.

1977 • 18 citations

THE PSYCHOBIOLOGY OF DEPRESSION

1976 • 17 citations

Controlled randomized group comparison of nomifensine and imipramine in depressive illness.

1977 • 17 citations

Some Effects of Mianserine (ORG GB 94) on Amine Metabolism in the Rat Brain

1977 • 12 citations

An X-Ray Diffraction Study of the Potentially Antidepressant Isomer of 3-(4-bromophenyl)-N,N-dimethyl-3-(3-pyridyl)allylamine.

1976 • 9 citations

Mianserin, an antidepressant with a unique neuropharmacological profile.

1978 • 7 citations

Effects of Various Drugs Supposed to Interact with Serotonin on PGO Frequency Changes Induced by Reserpine and 5-Hydroxytryptophan

2015 • 5 citations

Mianserin, an antidepressant with a unique neuropharmacological profile.

1978 • 5 citations

Lack of effect of chronically administered mianserin on the serotonergic system of the rat brain

1980 • 2 citations