Back to search

Randomized phase III study comparing irinotecan combined with 5-fluorouracil and folinic acid to cisplatin combined with 5-fluorouracil in chemotherapy naive patients with advanced adenocarcinoma of the stomach or esophagogastric junction

Data up to Jan 2025

Published2008
Citations344
References36

Total Citations Per Year

Abstract

References (36)

Reporting results of cancer treatment

1981 • 7,916 citations

Cancer Statistics, 2005

2005 • 5,487 citations

Phase III Study of Docetaxel and Cisplatin Plus Fluorouracil Compared With Cisplatin and Fluorouracil As First-Line Therapy for Advanced Gastric Cancer: A Report of the V325 Study Group

2006 • 1,874 citations

Capecitabine as Adjuvant Treatment for Stage III Colon Cancer

2005 • 1,212 citations

Chemotherapy in Advanced Gastric Cancer: A Systematic Review and Meta-Analysis Based on Aggregate Data

2006 • 1,146 citations

Randomized trial comparing epirubicin, cisplatin, and fluorouracil versus fluorouracil, doxorubicin, and methotrexate in advanced esophagogastric cancer.

1997 • 875 citations

Patterns of Initial Recurrence in Completely Resected Gastric Adenocarcinoma

2004 • 582 citations

Final Results of a Randomized Phase III Trial of Sequential High-Dose Methotrexate, Fluorouracil, and Doxorubicin Versus Etoposide, Leucovorin, and Fluorouracil Versus Infusional Fluorouracil and Cisplatin in Advanced Gastric Cancer: A Trial of the European Organization for Research and Treatment of Cancer Gastrointestinal Tract Cancer Cooperative Group

2000 • 536 citations

Multivariate Prognostic Factor Analysis in Locally Advanced and Metastatic Esophago-Gastric Cancer—Pooled Analysis From Three Multicenter, Randomized, Controlled Trials Using Individual Patient Data

2004 • 514 citations

Prospective Randomized Trial Comparing Mitomycin, Cisplatin, and Protracted Venous-Infusion Fluorouracil (PVI 5-FU) With Epirubicin, Cisplatin, and PVI 5-FU in Advanced Esophagogastric Cancer

2002 • 483 citations

Randomized Phase III Trial of Fluorouracil Alone Versus Fluorouracil Plus Cisplatin Versus Uracil and Tegafur Plus Mitomycin in Patients With Unresectable, Advanced Gastric Cancer: The Japan Clinical Oncology Group Study (JCOG9205)

2002 • 429 citations

A phase III randomized study of 5-fluorouracil and cisplatin versus 5-fluorouracil, doxorubicin, and mitomycin C versus 5-fluorouracil alone in the treatment of advanced gastric cancer

1993 • 360 citations

Phase II study of cetuximab in combination with FOLFIRI in patients with untreated advanced gastric or gastroesophageal junction adenocarcinoma (FOLCETUX study)

2006 • 285 citations

Long-term survival after epirubicin, cisplatin and fluorouracil for gastric cancer: results of a randomized trial

1999 • 279 citations

Randomized Multicenter Phase II Trial of a Biweekly Regimen of Fluorouracil and Leucovorin (LV5FU2), LV5FU2 Plus Cisplatin, or LV5FU2 Plus Irinotecan in Patients With Previously Untreated Metastatic Gastric Cancer: A Fédération Francophone de Cancérologie Digestive Group Study—FFCD 9803

2004 • 275 citations

Phase II Study of a Combination of Irinotecan and Cisplatin Against Metastatic Gastric Cancer

1999 • 272 citations

Clinical Benefit With Docetaxel Plus Fluorouracil and Cisplatin Compared With Cisplatin and Fluorouracil in a Phase III Trial of Advanced Gastric or Gastroesophageal Adenocarcinoma: The V-325 Study Group

2007 • 245 citations

Docetaxel, Cisplatin, and Fluorouracil; Docetaxel and Cisplatin; and Epirubicin, Cisplatin, and Fluorouracil As Systemic Treatment for Advanced Gastric Carcinoma: A Randomized Phase II Trial of the Swiss Group for Clinical Cancer Research

2007 • 245 citations

Design and analysis of non‐inferiority mortality trials in oncology

2002 • 236 citations

Points to consider on switching between superiority and non‐inferiority

2001 • 181 citations

[Late phase II study of irinotecan hydrochloride (CPT-11) in advanced gastric cancer. CPT-11 Gastrointestinal Cancer Study Group].

1994 • 171 citations

CPT‐11 plus cisplatin in patients with advanced, untreated gastric or gastroesophageal junction carcinoma

2002 • 166 citations

Irinotecan in combination with 5-fluorouracil and folinic acid or with cisplatin in patients with advanced gastric or esophageal-gastric junction adenocarcinoma: results of a randomized phase II study

2004 • 160 citations

A useful testing strategy in phase iii trials: combined test of superiority and test of equivalence

1995 • 140 citations

Phase I-II study of irinotecan hydrochloride combined with cisplatin in patients with advanced gastric cancer.

1997 • 139 citations

A Systematic Overview of Chemotherapy Effects in Gastric Cancer

2001 • 132 citations

Incidence and mortality from stomach cancer in Japan, Slovenia and the USA

2001 • 122 citations

Randomised multicentre phase III study comparing capecitabine with fluorouracil and oxaliplatin with cisplatin in patients with advanced oesophagogastric (OG) cancer: The REAL 2 trial

2006 • 108 citations

Randomised phase II evaluation of irinotecan plus high-dose 5-fluorouracil and leucovorin (ILF) vs 5-fluorouracil, leucovorin, and etoposide (ELF) in untreated metastatic gastric cancer

2005 • 98 citations

Irinotecan is active in chemonaive patients with metastatic gastric cancer: a phase II multicentric trial

2003 • 90 citations

Weekly Infusional High-Dose Fluorouracil (HD-FU), HD-FU Plus Folinic Acid (HD-FU/FA), or HD-FU/FA Plus Biweekly Cisplatin in Advanced Gastric Cancer: Randomized Phase II Trial 40953 of the European Organisation for Research and Treatment of Cancer Gastrointestinal Group and the Arbeitsgemeinschaft Internistische Onkologie

2007 • 69 citations

A Phase II Trial of Irinotecan in Patients with Previously Untreated Advanced Esophageal and Gastric Adenocarcinoma

2005 • 59 citations

Quality of life, appetite, and weight change in patients receiving dose-intensive chemotherapy.

1994 • 42 citations

Preliminary study of fortnightly irinotecan hydrochloride plus cisplatin therapy in patients with advanced gastric and colorectal cancer

2001 • 26 citations

A multicenter phase II study of irinotecan (CPT), cisplatin (CIS), and bevacizumab (BEV) in patients with unresectable or metastatic gastric or gastroesophageal junction (GEJ) adenocarcinoma

2005 • 19 citations

3518 POSTER Cetuximab with Irinotecan/FA/5-FU as first-line treatment in advanced gastric cancer: Preliminary results of a non-randomized multicenter AIO phase II study

2007 • 4 citations

Cited By (0)

No citing papers found in database

Randomized phase III study comparing irinotecan combined with 5-fluorouracil and folinic… (2008) – Annals of Oncology | Metascience Observatory Explorer