Assessment of brain perfusion with MRI: methodology and application to acute stroke

Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke. The European Cooperative Acute Stroke Study (ECASS)

1995 • 3,456 citations

Thresholds in cerebral ischemia - the ischemic penumbra.

1981 • 2,780 citations

High resolution measurement of cerebral blood flow using intravascular tracer bolus passages. Part I: Mathematical approach and statistical analysis

1996 • 1,510 citations

Viability thresholds and the penumbra of focal ischemia

1994 • 1,358 citations

Mr contrast due to intravascular magnetic susceptibility perturbations

1995 • 991 citations

High resolution measurement of cerebral blood flow using intravascular tracer bolus passages. Part II: Experimental comparison and preliminary results

1996 • 815 citations

Thrombolytic reversal of acute human cerebral ischemic injury shown by diffusion/perfusion magnetic resonance imaging

2000 • 683 citations

The ischemic penumbra

1999 • 648 citations

Quantification of regional cerebral blood flow and volume with dynamic susceptibility contrast-enhanced MR imaging.

1994 • 641 citations

Enlargement of human cerebral ischemic lesion volumes measured by diffusion‐weighted magnetic resonance imaging

1997 • 578 citations

Diffusion- and Perfusion-Weighted MRI

1999 • 578 citations

Prediction of stroke outcome with echoplanar perfusion- and diffusion-weighted MRI

1998 • 564 citations

Magnetic Resonance Imaging of Acute Stroke

1998 • 550 citations

Theoretical Basis of Indicator-Dilution Methods For Measuring Flow and Volume

1962 • 510 citations

Clinical experience with diffusion-weighted MR in patients with acute stroke.

1998 • 501 citations

Delay and dispersion effects in dynamic susceptibility contrast MRI: Simulations using singular value decomposition

2000 • 456 citations

Molecular diffusion nuclear magnetic resonance imaging.

1991 • 443 citations

Hyperacute Stroke: Simultaneous Measurement of Relative Cerebral Blood Volume, Relative Cerebral Blood Flow, and Mean Tissue Transit Time

1999 • 411 citations

Pitfalls in MR measurement of tissue blood flow with intravascular tracers: Which mean transit time?

1993 • 338 citations

CT and Conventional and Diffusion-weighted MR Imaging in Acute Stroke: Study in 691 Patients at Presentation to the Emergency Department

2002 • 337 citations

Evolution of Regional Changes in Apparent Diffusion Coefficient during Focal Ischemia of Rat Brain: The Relationship of Quantitative Diffusion NMR Imaging to Reduction in Cerebral Blood Flow and Metabolic Disturbances

1995 • 301 citations

Expanding the Window for Thrombolytic Therapy in Acute Stroke

1999 • 255 citations

Relationship between diffusion-weighted MR images, cerebral blood flow, and energy state in experimental brain infarction

1995 • 237 citations

Diffusion- and Perfusion-Weighted MRI

2000 • 230 citations

Cerebral Blood Flow Measurements by Magnetic Resonance Imaging Bolus Tracking: Comparison with [¹⁵O]H₂O Positron Emission Tomography in Humans

1998 • 217 citations

A. functional MRI technique combining principles of echo‐shifting with a train of observations (PRESTO)

1993 • 205 citations

Cerebral Hemodynamics in CADASIL Before and After Acetazolamide Challenge Assessed With MRI Bolus Tracking

2000 • 176 citations

Which MR-derived Perfusion Parameters are the Best Predictors of Infarct Growth in Hyperacute Stroke? Comparative Study between Relative and Quantitative Measurements

2002 • 172 citations

Absent middle cerebral artery flow predicts the presence and evolution of the ischemic penumbra

1999 • 151 citations

Usefulness of Magnetic Resonance–Derived Quantitative Measurements of Cerebral Blood Flow and Volume in Prediction of Infarct Growth in Hyperacute Stroke

2001 • 128 citations

Contrast agents in functional MR imaging

1997 • 111 citations

Whole brain quantitative CBF, CBV, and MTT measurements using MRI bolus tracking: Implementation and application to data acquired from hyperacute stroke patients

2000 • 110 citations

Multiparametric Imaging of Blood Flow and Metabolism after Middle Cerebral Artery Occlusion in Cats

1985 • 92 citations

Whole brain quantitative CBF and CBV measurements using MRI bolus tracking: Comparison of methodologies

2000 • 82 citations

Comparison of gradient- and spin-echo imaging: CBF, CBV, and MTT measurements by bolus tracking

2000 • 69 citations

Correlation of Regional Cerebral Blood Flow Measured by Stable Xenon CT and Perfusion MRI

1999 • 63 citations

Quantification of cerebral blood flow by bolus tracking and artery spin tagging methods

2000 • 56 citations

3D Bolus Tracking with Frequency-Shifted BURST MRI

1994 • 32 citations

Rapid Three-dimensional MR Imaging Method for Tracking a Bolus of Contrast Agent through the Brain

2000 • 31 citations

Perfusion fMRI with Arterial Spin Labeling

2000 • 26 citations

[Diffusion- and perfusion-weighted MR imaging during the hyperacute phase of stroke].

2000 • 15 citations

[Degree of hemodynamic disturbance at the hyperacute phase of stroke: predictive value of 3D-TOF angiography and the T2 fast-FLAIR sequence].

2000 • 4 citations