Construction of Transgenic Drosophila by Using the Site-Specific Integrase From Phage C31

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

1993 • 9,476 citations

Selective extraction of polyoma DNA from infected mouse cell cultures

1967 • 5,357 citations

A new member of the frizzled family from Drosophila functions as a Wingless receptor

1996 • 1,489 citations

Detection in situ of genomic regulatory elements in Drosophila.

1987 • 773 citations

A phage integrase directs efficient site-specific integration in human cells

2000 • 483 citations

In vitro site-specific integration of bacteriophage DNA catalyzed by a recombinase of the resolvase/invertase family

1998 • 417 citations

Site-Specific Genomic Integration in Mammalian Cells Mediated by Phage φC31 Integrase

2001 • 396 citations

Targeted mutagenesis by homologous recombination inD. melanogaster

2002 • 312 citations

Mammalian genomes contain active recombinase recognition sites

2000 • 285 citations

Site-specific genomic integration produces therapeutic Factor IX levels in mice

2002 • 285 citations

Effects of Genomic Position on the Expression of Transduced Copies of the white Gene of Drosophila

1985 • 253 citations

Stable nonviral genetic correction of inherited human skin disease

2002 • 249 citations

Transgene Coplacement and High Efficiency Site-Specific Recombination With the Cre/loxP System in Drosophila

1996 • 177 citations

A Targeted Gene Knockout in Drosophila

2001 • 163 citations

Transfected DNA is mutated in monkey, mouse, and human cells.

1984 • 138 citations

Injection of genetically engineered fibroblasts corrects regenerated human epidermolysis bullosa skin tissue

2003 • 132 citations

FLP-mediated DNA mobilization to specific target sites in Drosophila chromosomes

1997 • 112 citations

Phage R4 integrase mediates site-specific integration in human cells

2001 • 101 citations

φC31 Integrase-Mediated Nonviral Genetic Correction of Junctional Epidermolysis Bullosa

2003 • 93 citations

Application of Cre/loxP in Drosophila: Site-Specific Recombination and Transgene Coplacement

2003 • 80 citations

Phage TP901-1 Site-Specific Integrase Functions in Human Cells

2002 • 76 citations

Autonomous replication in Drosophila melanogaster tissue culture cells

1995 • 23 citations