Exploring Cells with a Centrifuge

Tissue fractionation studies. 6. Intracellular distribution patterns of enzymes in rat-liver tissue

1955 • 4,109 citations

Functions of Lysosomes

1966 • 2,942 citations

Lysosomotropic agents

1974 • 1,887 citations

Peroxisomes (microbodies and related particles).

1966 • 1,635 citations

THE LARGE-SCALE SEPARATION OF PEROXISOMES, MITOCHONDRIA, AND LYSOSOMES FROM THE LIVERS OF RATS INJECTED WITH TRITON WR-1339

1968 • 1,112 citations

INTRACELLULAR DISTRIBUTION OF ENZYMES

1948 • 1,108 citations

CYTOCHEMICAL STUDIES OF MAMMALIAN TISSUES

1948 • 981 citations

α-Glucosidase deficiency in generalized glycogen-storage disease (Pompe's disease)

1963 • 847 citations

ANALYTICAL STUDY OF MICROSOMES AND ISOLATED SUBCELLULAR MEMBRANES FROM RAT LIVER

1974 • 840 citations

Tissue fractionation studies. 5. The association of acid phosphatase with a special class of cytoplasmic granules in rat liver

1955 • 625 citations

PROTEIN DEGRADATION IN CULTURED CELLS

1974 • 603 citations

Microbodies-Peroxisomes and Glyoxysomes

1971 • 549 citations

INFLUENCE OF GLUCAGON, AN INDUCER OF CELLULAR AUTOPHAGY, ON SOME PHYSICAL PROPERTIES OF RAT LIVER LYSOSOMES

1967 • 509 citations

Hydrogenosome, a Cytoplasmic Organelle of the Anaerobic Flagellate Tritrichomonas foetus, and Its Role in Pyruvate Metabolism

1973 • 415 citations

LYSOSOMES OF THE ARTERIAL WALL

1972 • 410 citations

Tissue fractionation studies. 18. Resolution of mitochondrial fractions from rat liver into three distinct populations of cytoplasmic particles by means of density equilibration in various gradients

1964 • 346 citations

PARTICIPATION OF LYSOSOMES IN CELLULAR AUTOPHAGY INDUCED IN RAT LIVER BY GLUCAGON

1967 • 338 citations

TISSUE FRACTION-PAST AND PRESENT

1971 • 333 citations

ON THE MECHANISMS OF BONE RESORPTION

1968 • 331 citations

Tissue fraction-past and present.

1971 • 311 citations

RESOLUTION OF GRANULES FROM RABBIT HETEROPHIL LEUKOCYTES INTO DISTINCT POPULATIONS BY ZONAL SEDIMENTATION

1969 • 311 citations

ELECTRON MICROSCOPY OF LYSOSOME-RICH FRACTIONS FROM RAT LIVER

1956 • 311 citations

ANALYTICAL STUDY OF MICROSOMES AND ISOLATED SUBCELLULAR MEMBRANES FROM RAT LIVER

1974 • 294 citations

FRACTIONATION OF MAMMALIAN LIVER CELLS BY DIFFERENTIAL CENTRIFUGATION: I. PROBLEMS, METHODS, AND PREPARATION OF EXTRACT

1946 • 281 citations

FRACTIONATION OF MAMMALIAN LIVER CELLS BY DIFFERENTIAL CENTRIFUGATION

1946 • 277 citations

Chemotherapy through Lysosomes with a DNA-Daunorubicin Complex

1972 • 272 citations

ASSOCIATION OF LACTOFERRIN WITH SPECIFIC GRANULES IN RABBIT HETEROPHIL LEUKOCYTES

1970 • 266 citations

Tissue fractionation studies. 1. The existence of a mitochondria-linked, enzymically inactive form of acid phosphatase in rat-liver tissue

1951 • 262 citations

Digestive Activity of Lysosomes

1968 • 254 citations

ANALYTICAL STUDY OF MICROSOMES AND ISOLATED SUBCELLULAR MEMBRANES FROM RAT LIVER

1974 • 252 citations

COMBINED BIOCHEMICAL AND MORPHOLOGICAL STUDY OF PARTICULATE FRACTIONS FROM RAT LIVER

1965 • 250 citations

AN ELECTRON MICROSCOPIC AND BIOCHEMICAL STUDY OF TYPE II GLYCOGENOSIS.

1964 • 249 citations

Digestive Activity of Lysosomes

1969 • 246 citations

Effects of fat-soluble compounds on lysosomes in vitro

1962 • 238 citations

Digestive Activity of Lysosomes

1968 • 219 citations

Tissue fractionation studies. 10. Influence of ischaemia on the state of some bound enzymes in rat liver

1959 • 214 citations

ANALYTICAL STUDY OF MICROSOMES AND ISOLATED SUBCELLULAR MEMBRANES FROM RAT LIVER

1974 • 211 citations

Tissue fractionation studies. 2. The nature of the linkage between acid phosphatase and mitochondria in rat-liver tissue

1951 • 207 citations

LYSOSOMES IN LYMPHOID TISSUE

1967 • 206 citations

Distribution of Tricarboxylic Acid Cycle Enzymes and Glyoxylate Cycle Enzymes between Mitochondria and Peroxisomes in Tetrahymena pyriformis

1968 • 200 citations

THE SYNTHESIS AND TURNOVER OF RAT LIVER PEROXISOMES

1973 • 199 citations

The Use of Differential Centrifugation in the Study of Tissue Enzymes

1954 • 198 citations

Tissue fractionation studies. 16. Intracellular distribution and properties of α-glucosidases in rat liver

1963 • 196 citations

Gradient Centrifugation of Cell Particles Theory and Applications

1959 • 193 citations

The peroxisome: a new cytoplasmic organelle

1969 • 177 citations

THE SYNTHESIS AND TURNOVER OF RAT LIVER PEROXISOMES

1969 • 175 citations

Rule governing Cell Division in Anabaena

1972 • 174 citations

FROM CYTASES TO LYSOSOMES.

1964 • 168 citations

Studies on bone enzymes. The assay of acid hydrolases and other enzymes in bone tissue

1965 • 164 citations

Principles of tissue fractionation

1964 • 153 citations

FURTHER BIOCHEMICAL AND MORPHOLOGICAL STUDIES OF GRANULE FRACTIONS FROM RABBIT HETEROPHIL LEUKOCYTES

1970 • 153 citations

LYSOSOMES IN LYMPHOID TISSUE

1967 • 146 citations

ANALYTICAL FRACTIONATION OF HOMOGENATES FROM CULTURED RAT EMBRYO FIBROBLASTS

1974 • 135 citations

THE SYNTHESIS AND TURNOVER OF RAT LIVER PEROXISOMES

1969 • 131 citations

Lysosomes of the arterial wall

1974 • 129 citations

BIOCHEMICAL CYTOLOGY OF TRICHOMONAD FLAGELLATES

1973 • 124 citations

ELECTRON MICROSCOPE EXAMINATION OF SUBCELLULAR FRACTIONS

1971 • 109 citations

SECRETION OF ACID HYDROLASES AND ITS INTRACELLULAR SOURCE IN TETRAHYMENA PYRIFORMIS

1972 • 109 citations

Assay, Kinetics, and Lysosomal Localization of an Acid Cholesteryl Esterase in Rabbit Aortic Smooth Muscle Cells

1974 • 106 citations

Superoxide Dismutase in the Anaerobic Flagellates, Tritrichomonas foetus and Monocercomonas sp

1974 • 101 citations

THE ASSOCIATION OF CHOLESTEROL, 5'-NUCLEOTIDASE, AND ALKALINE PHOSPHODIESTERASE I WITH A DISTINCT GROUP OF MICROSOMAL PARTICLES

1969 • 100 citations

Tissue fractionation studies. 11. Influence of various hepatotoxic treatments on the state of some bound enzymes in rat liver

1959 • 99 citations

THE SYNTHESIS AND TURNOVER OF RAT LIVER PEROXISOMES

1973 • 94 citations

Non-mitochondrial oxidizing particles (microbodies) in rat liver and kidney and in Tetrahymena pyriformis

1965 • 94 citations

Experimental leukemia chemotherapy with a “lysosomotropic” adriamycin-DNA complex

1974 • 88 citations

Excretion of acid and of lysosomal hydrolytic enzymes during bone resorption induced in tissue culture by parathyroid extract

1965 • 86 citations

Lysosomes of the arterial wall. IV. Cytochemical localization of acid phosphatase and catalase in smooth muscle cells and foam cells from rabbit atheromatous aorta.

1974 • 82 citations

THE SYNTHESIS AND TURNOVER OF RAT LIVER PEROXISOMES

1970 • 72 citations

The development of zonal centrifuges and ancillary systems for tissue fractionation and analysis

1966 • 70 citations

Lysosomes in Tetrahymena pyriformis I. Some properties and lysosomal localization of acid hydrolases

1966 • 68 citations

PEROXISOMES IN TETRAHYMENA AND THEIR RELATION TO GLUCONEOGENESIS

1969 • 59 citations

LYSOSOMES IN LYMPHOID TISSUE

1967 • 56 citations

Studies on bone enzymes. The activation and release of latent acid hydrolases and catalase in bone-tissue homogenates

1965 • 51 citations

CYTOCHEMICAL LOCALIZATION OF ACID PHOSPHATASE ACTIVITY IN GRANULE FRACTIONS FROM RABBIT POLYMORPHONUCLEAR LEUKOCYTES

1972 • 50 citations

Lysosomal localization of sphingomyelinase in rat liver

1969 • 49 citations

SEDIMENTATION BEHAVIOR OF PROTEINS AND OTHER MATERIALS IN A HORIZONTAL PREPARATIVE ROTOR

1954 • 47 citations

Biochemical Cytology of Trichomonad Flagellates. II. Subcellular Distribution of Oxidoreductases and Hydrolases in Monocercomonas sp.*

1974 • 47 citations

Studies on bone enzymes. Distribution of acid hydrolases, alkaline phenylphosphatase, cytochrome oxidase and catalase in subcellular fraction of bone tissue homogenates

1965 • 44 citations

LYSOSOMES IN RAT THORACIC DUCT LYMPHOCYTES

1972 • 39 citations

Daunorubicin-DNA: Further clinical trials in acute non-lymphoblastic leukemia

1974 • 38 citations

Immunological Inhibition of Lysosome Function

1970 • 37 citations

Intermediates in the biosynthesis of peroxisomal catalase in rat liver

1971 • 37 citations

Behaviour of rat-liver mitochondria during centrifugation in a sucrose gradient

1974 • 33 citations

DNA-daunorubicin complex: Preliminary trials in human leukaemia

1973 • 31 citations

The influence of azodyes on lysosomal enzymes in rat liver.

1957 • 25 citations

Etude des hydrolases acides des canaux de Müller de l'embryon de Poulet

1962 • 24 citations

Causality and Anticipation

1975 • 22 citations

Lysosomes in Tetrahymena pyriformis. II. Intracellular distribution of several acid hydrolases.

1971 • 13 citations

Characteristics of lysosomes in the rat placental cells

1971 • 10 citations

LYSOSOMES IN RAT THORACIC DUCT LYMPHOCYTES FRACTIONATED BY ZONAL CENTRIFUGATION

1973 • 10 citations

Graft-Versus-Host and Cytotoxic Activity of Rat Thoracic Duct Lymphocytes Fractionated by Zonal Centrifugation after Culture on Allogeneic Fibroblasts

1974 • 3 citations