Intragenic Rearrangement and Altered RNA Splicing of the Androgen Receptor in a Cell-Based Model of Prostate Cancer Progression

Cancer Statistics, 2009

2009 • 9,675 citations

Using RepeatMasker to Identify Repetitive Elements in Genomic Sequences

2009 • 2,619 citations

The impact of retrotransposons on human genome evolution

2009 • 1,571 citations

In vivo amplification of the androgen receptor gene and progression of human prostate cancer

1995 • 1,464 citations

Understanding alternative splicing: towards a cellular code

2005 • 1,258 citations

Mutation of the Androgen-Receptor Gene in Metastatic Androgen-Independent Prostate Cancer

1995 • 1,251 citations

Mechanisms of change in gene copy number

2009 • 1,212 citations

Ligand-Independent Androgen Receptor Variants Derived from Splicing of Cryptic Exons Signify Hormone-Refractory Prostate Cancer

2008 • 1,044 citations

Splicing in disease: disruption of the splicing code and the decoding machinery

2007 • 998 citations

A Novel Androgen Receptor Splice Variant Is Up-regulated during Prostate Cancer Progression and Promotes Androgen Depletion–Resistant Growth

2009 • 848 citations

Complex landscapes of somatic rearrangement in human breast cancer genomes

2009 • 828 citations

Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing

2008 • 825 citations

Splicing of a Novel Androgen Receptor Exon Generates a Constitutively Active Androgen Receptor that Mediates Prostate Cancer Therapy Resistance

2008 • 808 citations

A Microhomology-Mediated Break-Induced Replication Model for the Origin of Human Copy Number Variation

2009 • 786 citations

Amplification and overexpression of androgen receptor gene in hormone-refractory prostate cancer.

2001 • 755 citations

Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant

2010 • 720 citations

Androgen Receptor (AR) Coregulators: A Diversity of Functions Converging on and Regulating the AR Transcriptional Complex

2007 • 706 citations

Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptor

2010 • 610 citations

Survey of gene amplifications during prostate cancer progression by high-throughout fluorescence in situ hybridization on tissue microarrays.

1999 • 606 citations

Selection for androgen receptor mutations in prostate cancers treated with androgen antagonist.

1999 • 592 citations

A new human prostate carcinoma cell line, 22Rv1

1999 • 563 citations

Characterization of ERG, AR and PTEN Gene Status in Circulating Tumor Cells from Patients with Castration-Resistant Prostate Cancer

2009 • 524 citations

Androgen receptor gene amplification and protein expression in hormone refractory prostate cancer

2003 • 424 citations

Androgen Receptor Mutations in Androgen-Independent Prostate Cancer: Cancer and Leukemia Group B Study 9663

2003 • 362 citations

Molecular evolution and tempo of amplification of human LINE-1 retrotransposons since the origin of primates

2005 • 341 citations

Mammalian non-LTR retrotransposons: For better or worse, in sickness and in health

2008 • 315 citations

Anti-androgens and androgen-depleting therapies in prostate cancer: new agents for an established target

2009 • 310 citations

Characterization of a novel androgen receptor mutation in a relapsed CWR22 prostate cancer xenograft and cell line.

2002 • 269 citations

Androgen receptor gene expression in human prostate carcinoma cell lines.

1990 • 220 citations

Architectures of somatic genomic rearrangement in human cancer amplicons at sequence-level resolution

2007 • 197 citations

Drug Insight: role of the androgen receptor in the development and progression of prostate cancer

2007 • 188 citations

Fluorescence In situ Hybridization Analysis of Circulating Tumor Cells in Metastatic Prostate Cancer

2009 • 186 citations

Regulation of DNA repair in hypoxic cancer cells

2007 • 183 citations

Distinct Genomic Alterations in Prostate Cancers in Chinese and Western Populations Suggest Alternative Pathways of Prostate Carcinogenesis

2010 • 158 citations

Ligand-independent Androgen Receptor Activity Is Activation Function-2-independent and Resistant to Antiandrogens in Androgen Refractory Prostate Cancer Cells

2006 • 110 citations

Androgen Receptor Alterations in Prostate Cancer Relapsed during a Combined Androgen Blockade by Orchiectomy and Bicalutamide

2001 • 103 citations

Androgen axis in prostate cancer

2006 • 100 citations

Regulation of androgen receptor signaling in prostate cancer

2005 • 89 citations

Pattern of Somatic Androgen Receptor Gene Mutations in Patients with Hormone-Refractory Prostate Cancer

2002 • 74 citations

Androgen-Regulated and Highly Tumorigenic Human Prostate Cancer Cell Line Established from a Transplantable Primary CWR22 Tumor

2008 • 43 citations

Androgen Receptor Mutations in High-Grade Prostate Cancer before Hormonal Therapy

2003 • 43 citations